Detailed information NTG1111743

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: HMPREF9425_RS04190
• Genome accession: NZ_GL831112
• Coordinates: 847121..848002 (+)
• Length: 293 a.a.
• NCBI ID: WP_003097029.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis ATCC 49124
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 842121..853002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS04165 (HMPREF9425_0868)	metK	842542..843735 (+)	1194	WP_003092628.1	methionine adenosyltransferase	-
HMPREF9425_RS04170 (HMPREF9425_0869)	galE	844093..845112 (+)	1020	WP_003097024.1	UDP-glucose 4-epimerase GalE	-
HMPREF9425_RS04175 (HMPREF9425_0870)	-	845294..845530 (+)	237	WP_003097025.1	DUF1146 family protein	-
HMPREF9425_RS04180 (HMPREF9425_0871)	murA	845598..846869 (+)	1272	WP_003097026.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
HMPREF9425_RS04185 (HMPREF9425_0872)	-	846871..847059 (+)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-
HMPREF9425_RS04190 (HMPREF9425_0873)	endA	847121..848002 (+)	882	WP_003097029.1	DNA/RNA non-specific endonuclease	Machinery gene
HMPREF9425_RS04195	-	848080..848196 (-)	117	Protein_848	amino acid ABC transporter permease	-
HMPREF9425_RS04200 (HMPREF9425_0876)	-	849106..849778 (-)	673	WP_003097031.1	transporter substrate-binding domain-containing protein	-
HMPREF9425_RS04205 (HMPREF9425_0877)	-	849788..850412 (-)	625	WP_003097033.1	amino acid ABC transporter ATP-binding protein	-
HMPREF9425_RS04210 (HMPREF9425_0878)	vicR	850735..851442 (+)	708	WP_003093060.1	response regulator YycF	Regulator
HMPREF9425_RS04215 (HMPREF9425_0879)	vicK	851435..852775 (+)	1341	WP_003097035.1	cell wall metabolism sensor histidine kinase VicK	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31564.30 Da
• Isoelectric Point: 10.3189

>NTDB_id=1111743 HMPREF9425_RS04190 WP_003097029.1 847121..848002(+) (endA) [Streptococcus vestibularis ATCC 49124]
MAKRKTSLTNKQKRQLVSLLIAILIAVLGYIGTSSKLSPNNPIKQVASLISGKSNNSVKSNGATKGQSTPQEKLAETVMT
SSVKSQLGNSLEWNGAGAYIVNGNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVHNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNTENIAVQTAWANQANSETSTGQNYYESLVRKAQDKNKRVR
YRVTLIYEGDNLIPSGSHLEAKSADGSLEFNVFVPNVQQGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1111743 HMPREF9425_RS04190 WP_003097029.1 847121..848002(+) (endA) [Streptococcus vestibularis ATCC 49124]
ATGGCAAAACGAAAGACATCTTTAACAAATAAACAGAAACGTCAGCTAGTCTCGTTGCTAATAGCAATCTTGATTGCAGT
TTTAGGTTACATTGGAACGAGCAGTAAGCTCTCGCCTAATAATCCAATCAAGCAGGTAGCAAGTCTAATCTCGGGAAAAT
CTAATAACTCTGTCAAATCAAACGGCGCAACAAAAGGGCAGTCTACACCACAAGAGAAGCTCGCTGAGACAGTGATGACT
AGCTCCGTCAAGAGTCAACTTGGAAACTCTTTAGAATGGAATGGGGCAGGGGCTTATATTGTTAATGGAAATAAGACTAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACAGTTCAAGGACAAACGGTTCCTACCGTTG
CGAATGCTTTGTTAAGTAAAGCGACCAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGCTCAACATCTTGGACACCA
GCTGGATGGCATCAAGTTCACAATCTTTCAGGAGAGTATAGCCATGCCGTAGACCGAGGTCATTTATTAGGCTATGCACT
TATAGGTGGTCTCAAAGGATTTGATGCCTCGACTTCAAATACAGAAAATATTGCTGTTCAAACTGCTTGGGCTAACCAAG
CTAATAGCGAAACTTCCACAGGTCAAAACTATTATGAAAGCCTGGTACGAAAAGCTCAGGATAAAAACAAACGTGTCCGT
TACCGTGTTACCCTCATTTATGAAGGAGACAACCTCATTCCATCAGGGTCACATCTTGAAGCCAAATCAGCTGATGGCTC
GCTTGAGTTCAATGTCTTTGTTCCAAATGTCCAACAGGGAATTACCCTAGATTATTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	71.146	86.348	0.614
endA	Streptococcus pneumoniae D39	71.146	86.348	0.614
endA	Streptococcus pneumoniae R6	71.146	86.348	0.614
endA	Streptococcus pneumoniae TIGR4	71.146	86.348	0.614