Detailed information NTG1111745

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: HMPREF9425_RS04215
• Genome accession: NZ_GL831112
• Coordinates: 851435..852775 (+)
• Length: 446 a.a.
• NCBI ID: WP_003097035.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis ATCC 49124
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 846435..857775

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS04185 (HMPREF9425_0872)	-	846871..847059 (+)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-
HMPREF9425_RS04190 (HMPREF9425_0873)	endA	847121..848002 (+)	882	WP_003097029.1	DNA/RNA non-specific endonuclease	Machinery gene
HMPREF9425_RS04195	-	848080..848196 (-)	117	Protein_848	amino acid ABC transporter permease	-
HMPREF9425_RS04200 (HMPREF9425_0876)	-	849106..849778 (-)	673	WP_003097031.1	transporter substrate-binding domain-containing protein	-
HMPREF9425_RS04205 (HMPREF9425_0877)	-	849788..850412 (-)	625	WP_003097033.1	amino acid ABC transporter ATP-binding protein	-
HMPREF9425_RS04210 (HMPREF9425_0878)	vicR	850735..851442 (+)	708	WP_003093060.1	response regulator YycF	Regulator
HMPREF9425_RS04215 (HMPREF9425_0879)	vicK	851435..852775 (+)	1341	WP_003097035.1	cell wall metabolism sensor histidine kinase VicK	Regulator
HMPREF9425_RS04220 (HMPREF9425_0880)	vicX	852781..853593 (+)	813	WP_037621682.1	MBL fold metallo-hydrolase	Regulator
HMPREF9425_RS04225 (HMPREF9425_0881)	-	853654..854013 (+)	360	WP_003097039.1	YbaN family protein	-
HMPREF9425_RS04230 (HMPREF9425_0882)	-	854068..855282 (-)	1215	WP_003097042.1	aminoacyltransferase	-
HMPREF9425_RS04235 (HMPREF9425_0883)	yidA	855284..856093 (-)	810	WP_003097045.1	sugar-phosphatase	-
HMPREF9425_RS04240 (HMPREF9425_0884)	-	856271..857134 (+)	864	WP_003097048.1	GNAT family N-acetyltransferase	-
HMPREF9425_RS04245 (HMPREF9425_0885)	-	857209..857595 (+)	387	WP_002884910.1	DUF1934 domain-containing protein	-

Sequence

Protein

• Length: 446 a.a.
• Molecular weight: 50994.34 Da
• Isoelectric Point: 6.2838

>NTDB_id=1111745 HMPREF9425_RS04215 WP_003097035.1 851435..852775(+) (vicK) [Streptococcus vestibularis ATCC 49124]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRQAKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELADRLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDRESATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALHE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNPGKFYEIIRDYSVNSI
WVEIDTDKMTRVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide

• Length: 1341 bp

>NTDB_id=1111745 HMPREF9425_RS04215 WP_003097035.1 851435..852775(+) (vicK) [Streptococcus vestibularis ATCC 49124]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTATTTGTTGCTTTCTATTTTAT
TTTTTTAGCTTATCGTGATTATCGACAAGCTAAAAATATCCGAAAGTTGACTAAGAGAGTCAAGTCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCGGATCGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCGTGGTCAGATTACCATGATTAATAGCACTGCTCAACGCTTGTTGAATTTAGATCGCGAAAGTGCGA
CTCAGATGTCTATTTTGGATTTATTAGATGGTGAGAATCCCTACACCTATAGTGAATTGTTGTCTAAGACCCCCGAAATC
CATCTGTCGCGTCGAGATGCTAATGATGAATTTGTGACGCTACGTGTTAATTTTGCACTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAACAGGAAAAAGAGGAGCGTGAACGTCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACACCTTTGACTTCAGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCCACGAA
GAAATTGCTCCAAACTTTATTAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
GTCTCGAATTGACAATAAAAGCACACAGCTTGATGTCGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGATCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTTTTATGAAATCATTAGAGATTACTCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACTCGGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACGACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAGGATTTGCCGTTGATTTTCGACCGTTTTTACCGCGTTGATAAGGCCAGAAGTCGTGCTCAAGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (208-272)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (325-435)

• PAS fold (PAS) (94-197)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.913	92.825	0.686
micB	Streptococcus pneumoniae Cp1015	67.206	97.085	0.652