Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HMPREF9319_RS04575 Genome accession   NZ_GL397128
Coordinates   953602..954444 (-) Length   280 a.a.
NCBI ID   WP_003064756.1    Uniprot ID   E0PDM2
Organism   Streptococcus equinus ATCC 700338     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 948602..959444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS04555 (HMPREF9319_0941) - 949047..949529 (-) 483 WP_003064748.1 hypothetical protein -
  HMPREF9319_RS04560 (HMPREF9319_0942) - 949546..950265 (-) 720 WP_003064750.1 DUF3307 domain-containing protein -
  HMPREF9319_RS04565 (HMPREF9319_0943) - 950265..950930 (-) 666 WP_003064752.1 SatD family protein -
  HMPREF9319_RS04570 (HMPREF9319_0944) topA 951078..953225 (-) 2148 WP_041973403.1 type I DNA topoisomerase -
  HMPREF9319_RS04575 (HMPREF9319_0945) dprA 953602..954444 (-) 843 WP_003064756.1 DNA-processing protein DprA Machinery gene
  HMPREF9319_RS04580 (HMPREF9319_0946) - 954519..955070 (-) 552 WP_003064760.1 sugar O-acetyltransferase -
  HMPREF9319_RS04585 (HMPREF9319_0947) - 955072..955851 (-) 780 WP_003064763.1 ribonuclease HII -
  HMPREF9319_RS04590 (HMPREF9319_0948) ylqF 955838..956692 (-) 855 WP_003064765.1 ribosome biogenesis GTPase YlqF -
  HMPREF9319_RS04595 - 957091..957204 (-) 114 Protein_921 sigma-70 family RNA polymerase sigma factor -
  HMPREF9319_RS04600 (HMPREF9319_0950) - 957501..958505 (-) 1005 WP_003064769.1 sensor histidine kinase -
  HMPREF9319_RS04605 (HMPREF9319_0951) - 958502..959161 (-) 660 WP_041973406.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31027.10 Da        Isoelectric Point: 8.3615

>NTDB_id=1111687 HMPREF9319_RS04575 WP_003064756.1 953602..954444(-) (dprA) [Streptococcus equinus ATCC 700338]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDIKELRKEFNCFPSVSILDDEYP
LELKHCYNPPVLLFYQGNLELLNRPKMAVVGARTASATGTKSVQKIVKELGNHFVIVSGLARGIDTSAHLSSLKNGGASI
AVIGCGLDVYYPKENKQLQEYMVKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVTSGLDILSEYQI

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1111687 HMPREF9319_RS04575 WP_003064756.1 953602..954444(-) (dprA) [Streptococcus equinus ATCC 700338]
ATGAATAATTTTGAATTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACATCAAAGAATTGCGCAAAGAATTTAATTGTTTTCCTAGTGTTTCCATACTAGATGACGAATACCCA
TTAGAACTCAAACATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAATTACTCAATCGCCCAAAAAT
GGCAGTAGTAGGAGCAAGAACAGCATCAGCAACAGGGACAAAATCCGTACAGAAAATTGTCAAAGAACTCGGGAATCATT
TTGTTATCGTTAGTGGGTTGGCGCGTGGCATTGATACCAGTGCGCATTTATCATCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGTGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGAGTACATGGTTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAGGGCGCAAAATG
CGTCACATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PDM2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

74.46

99.286

0.739
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.929

100

0.639
  dprA/cilB/dalA Streptococcus mitis SK321

63.929

100

0.639
  dprA Lactococcus lactis subsp. cremoris KW2

61.871

99.286

0.614
  dprA Legionella pneumophila strain ERS1305867

42.739

86.071

0.368
  dprA Haemophilus influenzae Rd KW20

38.258

94.286

0.361

Multiple sequence alignment