Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | ACM3HZ_RS03935 | Genome accession | NZ_CP180684 |
| Coordinates | 683254..683442 (+) | Length | 62 a.a. |
| NCBI ID | WP_000027835.1 | Uniprot ID | A0AAV3JNT7 |
| Organism | Streptococcus agalactiae strain M18 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 666566..685072 | 683254..683442 | within | 0 |
| IS/Tn | 682187..682798 | 683254..683442 | flank | 456 |
Gene organization within MGE regions
Location: 666566..685072
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACM3HZ_RS03815 (ACM3HZ_03815) | - | 666566..667645 (-) | 1080 | WP_000264730.1 | tyrosine-type recombinase/integrase | - |
| ACM3HZ_RS03820 (ACM3HZ_03820) | - | 667768..667971 (-) | 204 | WP_000505363.1 | hypothetical protein | - |
| ACM3HZ_RS03825 (ACM3HZ_03825) | - | 668074..668631 (-) | 558 | WP_000891067.1 | GTP pyrophosphokinase | - |
| ACM3HZ_RS03830 (ACM3HZ_03830) | - | 668633..669355 (-) | 723 | WP_050151496.1 | XRE family transcriptional regulator | - |
| ACM3HZ_RS03835 (ACM3HZ_03835) | - | 669870..670067 (-) | 198 | WP_000703682.1 | hypothetical protein | - |
| ACM3HZ_RS03840 (ACM3HZ_03840) | - | 670126..670284 (+) | 159 | WP_001104146.1 | hypothetical protein | - |
| ACM3HZ_RS03845 (ACM3HZ_03845) | - | 670325..670462 (+) | 138 | WP_017644741.1 | hypothetical protein | - |
| ACM3HZ_RS03850 (ACM3HZ_03850) | - | 670431..671126 (-) | 696 | WP_000039331.1 | hypothetical protein | - |
| ACM3HZ_RS03855 (ACM3HZ_03855) | - | 671179..671439 (+) | 261 | WP_017285238.1 | hypothetical protein | - |
| ACM3HZ_RS03860 (ACM3HZ_03860) | - | 671410..671634 (-) | 225 | WP_017285239.1 | hypothetical protein | - |
| ACM3HZ_RS03865 (ACM3HZ_03865) | - | 671707..671889 (+) | 183 | WP_050896440.1 | helix-turn-helix domain-containing protein | - |
| ACM3HZ_RS03875 (ACM3HZ_03875) | prx | 673105..673308 (+) | 204 | WP_194687768.1 | Paratox | Regulator |
| ACM3HZ_RS03880 (ACM3HZ_03880) | - | 673289..673990 (-) | 702 | WP_242023731.1 | site-specific integrase | - |
| ACM3HZ_RS03885 (ACM3HZ_03885) | - | 674026..674292 (-) | 267 | WP_001872365.1 | hypothetical protein | - |
| ACM3HZ_RS03890 (ACM3HZ_03890) | - | 674298..675675 (+) | 1378 | Protein_684 | IS3 family transposase | - |
| ACM3HZ_RS03895 (ACM3HZ_03895) | - | 675848..676009 (-) | 162 | WP_000508795.1 | TM2 domain-containing protein | - |
| ACM3HZ_RS03900 (ACM3HZ_03900) | - | 676752..678029 (+) | 1278 | WP_000594360.1 | ABC transporter permease | - |
| ACM3HZ_RS03905 (ACM3HZ_03905) | - | 678039..678695 (+) | 657 | WP_000353149.1 | ABC transporter ATP-binding protein | - |
| ACM3HZ_RS03910 (ACM3HZ_03910) | - | 678695..680069 (+) | 1375 | Protein_688 | ABC transporter permease | - |
| ACM3HZ_RS03915 (ACM3HZ_03915) | - | 680166..680819 (+) | 654 | WP_000699093.1 | response regulator transcription factor | - |
| ACM3HZ_RS03920 (ACM3HZ_03920) | - | 680816..682135 (+) | 1320 | WP_000734169.1 | sensor histidine kinase | - |
| ACM3HZ_RS03925 (ACM3HZ_03925) | - | 682187..682834 (-) | 648 | Protein_691 | IS3 family transposase | - |
| ACM3HZ_RS03930 (ACM3HZ_03930) | - | 683012..683212 (+) | 201 | WP_000076708.1 | CsbD family protein | - |
| ACM3HZ_RS03935 (ACM3HZ_03935) | prx | 683254..683442 (+) | 189 | WP_000027835.1 | hypothetical protein | Regulator |
| ACM3HZ_RS03940 (ACM3HZ_03940) | - | 683867..685072 (+) | 1206 | WP_000078931.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7180.25 Da Isoelectric Point: 4.7815
>NTDB_id=1097359 ACM3HZ_RS03935 WP_000027835.1 683254..683442(+) (prx) [Streptococcus agalactiae strain M18]
MSIRTDIDEFKEAIDKGYISGNTVAIVRKNGKIFDYVLLHEEVREEEVVTVERVLDVLRKLS
MSIRTDIDEFKEAIDKGYISGNTVAIVRKNGKIFDYVLLHEEVREEEVVTVERVLDVLRKLS
Nucleotide
Download Length: 189 bp
>NTDB_id=1097359 ACM3HZ_RS03935 WP_000027835.1 683254..683442(+) (prx) [Streptococcus agalactiae strain M18]
TTGTCTATCAGAACAGATATAGATGAGTTTAAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGT
GCGTAAAAACGGAAAGATATTTGATTATGTGTTACTACACGAAGAAGTGAGAGAAGAAGAGGTTGTTACAGTTGAGAGAG
TGCTTGATGTACTGAGGAAGTTATCATAA
TTGTCTATCAGAACAGATATAGATGAGTTTAAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGT
GCGTAAAAACGGAAAGATATTTGATTATGTGTTACTACACGAAGAAGTGAGAGAAGAAGAGGTTGTTACAGTTGAGAGAG
TGCTTGATGTACTGAGGAAGTTATCATAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
72.222 |
87.097 |
0.629 |
| prx | Streptococcus pyogenes MGAS8232 |
69.091 |
88.71 |
0.613 |
| prx | Streptococcus pyogenes MGAS315 |
66.667 |
87.097 |
0.581 |
| prx | Streptococcus pyogenes MGAS315 |
85 |
64.516 |
0.548 |
| prx | Streptococcus pyogenes MGAS315 |
61.818 |
88.71 |
0.548 |
| prx | Streptococcus pyogenes MGAS315 |
74.359 |
62.903 |
0.468 |
| prx | Streptococcus pyogenes MGAS315 |
78.378 |
59.677 |
0.468 |