Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ACM3HZ_RS03875 Genome accession   NZ_CP180684
Coordinates   673105..673308 (+) Length   67 a.a.
NCBI ID   WP_194687768.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain M18     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 666566..685072 673105..673308 within 0
IScluster/Tn 671907..674696 673105..673308 within 0


Gene organization within MGE regions


Location: 666566..685072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM3HZ_RS03815 (ACM3HZ_03815) - 666566..667645 (-) 1080 WP_000264730.1 tyrosine-type recombinase/integrase -
  ACM3HZ_RS03820 (ACM3HZ_03820) - 667768..667971 (-) 204 WP_000505363.1 hypothetical protein -
  ACM3HZ_RS03825 (ACM3HZ_03825) - 668074..668631 (-) 558 WP_000891067.1 GTP pyrophosphokinase -
  ACM3HZ_RS03830 (ACM3HZ_03830) - 668633..669355 (-) 723 WP_050151496.1 XRE family transcriptional regulator -
  ACM3HZ_RS03835 (ACM3HZ_03835) - 669870..670067 (-) 198 WP_000703682.1 hypothetical protein -
  ACM3HZ_RS03840 (ACM3HZ_03840) - 670126..670284 (+) 159 WP_001104146.1 hypothetical protein -
  ACM3HZ_RS03845 (ACM3HZ_03845) - 670325..670462 (+) 138 WP_017644741.1 hypothetical protein -
  ACM3HZ_RS03850 (ACM3HZ_03850) - 670431..671126 (-) 696 WP_000039331.1 hypothetical protein -
  ACM3HZ_RS03855 (ACM3HZ_03855) - 671179..671439 (+) 261 WP_017285238.1 hypothetical protein -
  ACM3HZ_RS03860 (ACM3HZ_03860) - 671410..671634 (-) 225 WP_017285239.1 hypothetical protein -
  ACM3HZ_RS03865 (ACM3HZ_03865) - 671707..671889 (+) 183 WP_050896440.1 helix-turn-helix domain-containing protein -
  ACM3HZ_RS03875 (ACM3HZ_03875) prx 673105..673308 (+) 204 WP_194687768.1 Paratox Regulator
  ACM3HZ_RS03880 (ACM3HZ_03880) - 673289..673990 (-) 702 WP_242023731.1 site-specific integrase -
  ACM3HZ_RS03885 (ACM3HZ_03885) - 674026..674292 (-) 267 WP_001872365.1 hypothetical protein -
  ACM3HZ_RS03890 (ACM3HZ_03890) - 674298..675675 (+) 1378 Protein_684 IS3 family transposase -
  ACM3HZ_RS03895 (ACM3HZ_03895) - 675848..676009 (-) 162 WP_000508795.1 TM2 domain-containing protein -
  ACM3HZ_RS03900 (ACM3HZ_03900) - 676752..678029 (+) 1278 WP_000594360.1 ABC transporter permease -
  ACM3HZ_RS03905 (ACM3HZ_03905) - 678039..678695 (+) 657 WP_000353149.1 ABC transporter ATP-binding protein -
  ACM3HZ_RS03910 (ACM3HZ_03910) - 678695..680069 (+) 1375 Protein_688 ABC transporter permease -
  ACM3HZ_RS03915 (ACM3HZ_03915) - 680166..680819 (+) 654 WP_000699093.1 response regulator transcription factor -
  ACM3HZ_RS03920 (ACM3HZ_03920) - 680816..682135 (+) 1320 WP_000734169.1 sensor histidine kinase -
  ACM3HZ_RS03925 (ACM3HZ_03925) - 682187..682834 (-) 648 Protein_691 IS3 family transposase -
  ACM3HZ_RS03930 (ACM3HZ_03930) - 683012..683212 (+) 201 WP_000076708.1 CsbD family protein -
  ACM3HZ_RS03935 (ACM3HZ_03935) prx 683254..683442 (+) 189 WP_000027835.1 hypothetical protein Regulator
  ACM3HZ_RS03940 (ACM3HZ_03940) - 683867..685072 (+) 1206 WP_000078931.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 67 a.a.        Molecular weight: 7890.02 Da        Isoelectric Point: 4.3219

>NTDB_id=1097358 ACM3HZ_RS03875 WP_194687768.1 673105..673308(+) (prx) [Streptococcus agalactiae strain M18]
MSTFIVYIQLYIDELQEAIDKGYISGNTVAIVRKNGKIFDYVLPHEEVREEEVVTVERVEDVMRELR

Nucleotide


Download         Length: 204 bp        

>NTDB_id=1097358 ACM3HZ_RS03875 WP_194687768.1 673105..673308(+) (prx) [Streptococcus agalactiae strain M18]
TTGTCTACTTTTATAGTATACATCCAGTTATATATAGATGAGCTACAAGAAGCGATTGATAAAGGCTATATTTCAGGGAA
CACAGTAGCGATAGTGCGTAAGAACGGAAAGATATTTGATTATGTGTTACCACACGAAGAAGTGAGAGAAGAAGAGGTTG
TGACAGTTGAGAGAGTGGAAGACGTTATGAGAGAATTGAGGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

70.175

85.075

0.597
  prx Streptococcus pyogenes MGAS8232

66.667

85.075

0.567
  prx Streptococcus pyogenes MGAS315

66.667

85.075

0.567
  prx Streptococcus pyogenes MGAS315

83.333

62.687

0.522
  prx Streptococcus pyogenes MGAS315

59.649

85.075

0.507
  prx Streptococcus pyogenes MGAS315

69.048

62.687

0.433
  prx Streptococcus pyogenes MGAS315

70.732

61.194

0.433

Multiple sequence alignment