Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACMHDP_RS09250 Genome accession   NZ_CP180195
Coordinates   1777257..1778501 (-) Length   414 a.a.
NCBI ID   WP_016176087.1    Uniprot ID   -
Organism   Enterococcus saccharolyticus strain GXN23C125Es     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1772257..1783501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMHDP_RS09225 (ACMHDP_09225) - 1773496..1773741 (-) 246 WP_016176092.1 hypothetical protein -
  ACMHDP_RS09230 (ACMHDP_09230) - 1773738..1773932 (-) 195 WP_016176091.1 hypothetical protein -
  ACMHDP_RS09235 (ACMHDP_09235) - 1774002..1774217 (-) 216 WP_016176090.1 hypothetical protein -
  ACMHDP_RS09240 (ACMHDP_09240) rny 1774284..1775840 (-) 1557 WP_414840873.1 ribonuclease Y -
  ACMHDP_RS09245 (ACMHDP_09245) recA 1776106..1777146 (-) 1041 WP_016176088.1 recombinase RecA Machinery gene
  ACMHDP_RS09250 (ACMHDP_09250) cinA 1777257..1778501 (-) 1245 WP_016176087.1 competence/damage-inducible protein A Machinery gene
  ACMHDP_RS09255 (ACMHDP_09255) pgsA 1778627..1779208 (-) 582 WP_016176086.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACMHDP_RS09260 (ACMHDP_09260) - 1779249..1780130 (-) 882 WP_414840874.1 helix-turn-helix domain-containing protein -
  ACMHDP_RS09265 (ACMHDP_09265) yfmH 1780233..1781528 (-) 1296 WP_414840875.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ACMHDP_RS09270 (ACMHDP_09270) yfmF 1781530..1782789 (-) 1260 WP_414840876.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  ACMHDP_RS09275 (ACMHDP_09275) mscL 1782946..1783416 (+) 471 WP_414842289.1 large conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45447.51 Da        Isoelectric Point: 4.5299

>NTDB_id=1094453 ACMHDP_RS09250 WP_016176087.1 1777257..1778501(-) (cinA) [Enterococcus saccharolyticus strain GXN23C125Es]
MKAEIIAVGTELLLGQVVNTNATFLSEELAGLGIDVYYHSVVGDNAERLESLLELADQRSELIVLCGGLGPTEDDLTKQV
TAAHVGQELVRDEVGYQNLLSFFEKRQRPMTENNLLQTLVFKEGISLQNSAGLAVGIFYTSIKGNHYLLLPGPPSELKPM
FYHEVVPLLQKQFQKEEQLISRVLRFYGIGESQLVTDLADLIQGQTNPTIAPYAKPNEVTLRLTVKTTDETEAITQLDVL
EAVIQERVGEFFYGYGEENSLANVVVDLLKEKQQTLTAAESLTAGAFQSALGDISGVSEVFLGGFVTYSAQTKANFLGID
RDFLEQVGTVSQACVEQMALHARKLAQTDYSVAFSGVAGPNELEGQPAGTVWIALASEQGVHSQKYHFSRDRSYIRHSAV
MAGLDLLRRELLNK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=1094453 ACMHDP_RS09250 WP_016176087.1 1777257..1778501(-) (cinA) [Enterococcus saccharolyticus strain GXN23C125Es]
ATGAAGGCAGAAATTATTGCAGTAGGAACCGAGTTGTTATTGGGGCAAGTAGTCAATACAAATGCGACTTTTTTATCAGA
AGAATTAGCAGGATTAGGCATTGATGTTTATTATCATAGCGTGGTAGGTGATAATGCAGAACGTTTGGAATCATTGCTAG
AGTTAGCAGATCAACGTAGTGAATTGATTGTTTTGTGTGGGGGCTTAGGACCCACCGAAGACGATTTAACCAAACAAGTC
ACAGCAGCGCATGTAGGGCAAGAATTAGTGCGCGATGAAGTAGGGTATCAAAATTTACTATCATTTTTTGAAAAACGCCA
ACGCCCTATGACGGAAAATAATCTTTTGCAAACGTTAGTTTTTAAAGAAGGTATTTCATTGCAAAATAGCGCTGGTTTAG
CGGTAGGTATCTTTTATACTTCTATTAAGGGAAATCATTACTTACTACTTCCAGGCCCCCCTAGCGAGCTAAAACCGATG
TTCTATCACGAAGTCGTACCTTTGCTTCAAAAACAATTCCAAAAAGAAGAACAATTAATTTCTCGTGTGTTACGTTTTTA
TGGGATTGGTGAATCACAATTAGTTACGGACTTAGCAGATTTGATTCAAGGCCAAACGAATCCTACGATTGCGCCTTATG
CAAAACCAAATGAAGTAACGTTGCGTTTAACGGTCAAAACAACCGATGAAACCGAAGCAATCACTCAACTGGATGTATTA
GAAGCAGTCATTCAAGAACGAGTCGGCGAATTTTTCTATGGTTATGGCGAGGAAAATTCATTGGCTAATGTCGTGGTTGA
TTTATTAAAAGAAAAACAGCAAACTTTAACAGCCGCAGAAAGTCTCACAGCAGGCGCTTTTCAGTCAGCATTAGGAGATA
TTTCTGGTGTTTCTGAAGTGTTTTTGGGTGGATTTGTCACATATTCTGCACAAACAAAAGCGAATTTTCTAGGAATTGAT
CGCGACTTTTTAGAACAAGTTGGCACAGTGAGTCAAGCATGTGTTGAACAAATGGCTCTGCATGCACGCAAATTGGCACA
GACAGATTATTCAGTAGCTTTTAGTGGGGTAGCTGGACCAAATGAATTAGAAGGGCAACCAGCGGGAACTGTGTGGATTG
CTTTAGCAAGTGAGCAAGGTGTCCATAGTCAAAAATACCATTTTAGTAGAGATCGCAGTTACATTCGTCATAGTGCAGTA
ATGGCAGGACTTGATTTGCTTCGTCGAGAACTTCTAAATAAATAG

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.717

100

0.541
  cinA Streptococcus mitis NCTC 12261

52.123

100

0.534
  cinA Streptococcus mitis SK321

51.887

100

0.531
  cinA Streptococcus pneumoniae TIGR4

51.185

100

0.522
  cinA Streptococcus pneumoniae D39

50.948

100

0.519
  cinA Streptococcus pneumoniae Rx1

50.948

100

0.519
  cinA Streptococcus pneumoniae R6

50.948

100

0.519
  cinA Bacillus subtilis subsp. subtilis str. 168

46.731

99.758

0.466
  cinA Streptococcus suis isolate S10

45.06

100

0.452

Multiple sequence alignment