Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   ACLKML_RS12120 Genome accession   NZ_CP178628
Coordinates   979068..980174 (+) Length   368 a.a.
NCBI ID   WP_413285532.1    Uniprot ID   -
Organism   Vibrio sp. MA40-2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 974068..985174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLKML_RS12100 (ACLKML_12100) trkA 974538..975914 (-) 1377 WP_413285529.1 Trk system potassium transporter TrkA -
  ACLKML_RS12105 (ACLKML_12105) rsmB 975988..977268 (-) 1281 WP_413285530.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACLKML_RS12110 (ACLKML_12110) fmt 977369..978316 (-) 948 WP_413285531.1 methionyl-tRNA formyltransferase -
  ACLKML_RS12115 (ACLKML_12115) def 978327..978842 (-) 516 WP_317718159.1 peptide deformylase -
  ACLKML_RS12120 (ACLKML_12120) dprA 979068..980174 (+) 1107 WP_413285532.1 DNA-processing protein DprA Machinery gene
  ACLKML_RS12125 (ACLKML_12125) - 980177..980650 (+) 474 WP_317718161.1 DUF494 family protein -
  ACLKML_RS12130 (ACLKML_12130) - 980672..981253 (+) 582 WP_413285533.1 type I DNA topoisomerase -
  ACLKML_RS12135 (ACLKML_12135) - 981293..982441 (-) 1149 WP_413285876.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  ACLKML_RS12140 (ACLKML_12140) purE 982444..982929 (-) 486 WP_317718163.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  ACLKML_RS12145 (ACLKML_12145) - 983232..983804 (+) 573 WP_317718164.1 L-threonylcarbamoyladenylate synthase -
  ACLKML_RS12150 (ACLKML_12150) hemF 983851..984759 (+) 909 WP_413285534.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 368 a.a.        Molecular weight: 40065.02 Da        Isoelectric Point: 7.5536

>NTDB_id=1090690 ACLKML_RS12120 WP_413285532.1 979068..980174(+) (dprA) [Vibrio sp. MA40-2]
MNENKLSAWLTLSFTPAIGSKSFSKLVAIDSVENIVNYPTKNLEMLGFNNSQIDYIKHKAKKEIEACLFWQQQSPSHRII
TLLDSEYPRLLKQINLPPPVLFVKGKIDVLSEPQIAIVGSRNASVDGLNNAKLFAGDLARKGITVTSGMALGVDGHAHDG
ALKSGGETIAVLGSGLNNIYPAKHRVLSERIVESGVLVSEFRPNGVARPENFPRRNRIISGLSMGVLVVEATKKSGSLIT
ARYAMEQGREVFALPGSIHNPLAKGGNALIKDGANLVQSSNEMLKEIDVLLNWSLNSQKELFADEVSNEQLPFSLVLANV
GEDEAISVDILAQRTHISVHEIMIQLLELELQGQVAAVSGGYIRTRRT

Nucleotide


Download         Length: 1107 bp        

>NTDB_id=1090690 ACLKML_RS12120 WP_413285532.1 979068..980174(+) (dprA) [Vibrio sp. MA40-2]
ATGAATGAAAATAAGCTTTCAGCATGGTTAACATTAAGTTTTACACCTGCCATTGGGAGTAAAAGTTTTAGCAAATTAGT
CGCTATAGATTCAGTCGAAAATATTGTTAATTATCCTACCAAAAATTTAGAAATGCTTGGTTTTAATAATTCGCAAATAG
ATTACATAAAACATAAAGCGAAGAAAGAGATTGAAGCTTGTTTATTTTGGCAACAACAATCCCCTAGCCATAGAATCATT
ACTTTATTAGACAGCGAATACCCTAGACTTCTTAAACAGATAAATCTTCCGCCACCAGTTTTGTTTGTTAAAGGAAAAAT
CGATGTTTTATCTGAACCTCAAATAGCCATTGTAGGTAGCAGAAACGCCAGTGTTGATGGACTCAATAATGCTAAATTGT
TTGCAGGCGATTTGGCTCGCAAAGGAATAACCGTTACCAGTGGCATGGCTTTAGGTGTAGATGGTCATGCACATGATGGT
GCGTTAAAGTCTGGTGGCGAGACGATAGCGGTTTTAGGTTCAGGTTTAAATAATATTTACCCTGCTAAGCATAGGGTGTT
ATCAGAAAGAATTGTTGAAAGTGGTGTGCTAGTTTCAGAGTTTAGGCCGAATGGTGTGGCGAGGCCGGAAAATTTCCCAC
GTAGAAATAGGATTATTAGTGGTTTATCGATGGGGGTGTTAGTGGTTGAAGCAACCAAAAAAAGTGGTTCATTAATTACA
GCTCGGTATGCAATGGAGCAAGGGCGAGAAGTCTTCGCTTTACCTGGATCGATCCATAATCCATTGGCTAAAGGTGGAAA
CGCATTAATCAAAGATGGGGCAAATCTTGTCCAGTCCTCTAATGAGATGCTTAAAGAAATAGACGTCTTACTTAATTGGT
CGTTAAATAGCCAGAAAGAGCTTTTTGCTGATGAAGTTAGTAATGAGCAATTGCCATTTTCTCTCGTCTTGGCTAACGTA
GGAGAGGATGAAGCAATATCAGTTGATATTTTGGCACAGAGAACCCATATTTCTGTACATGAAATTATGATTCAACTTTT
GGAGCTTGAACTTCAGGGGCAAGTCGCTGCTGTATCTGGCGGGTATATTCGAACGAGGAGGACCTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(76-278)

DprA winged helix domain (DprA_WH)

(316-361)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

59.836

99.457

0.595
  dprA Vibrio cholerae strain A1552

52.561

100

0.53
  dprA Glaesserella parasuis strain SC1401

45.989

100

0.467
  dprA Neisseria meningitidis strain C311

39.401

100

0.429
  dprA Neisseria meningitidis MC58

39.401

100

0.429
  dprA Legionella pneumophila strain ERS1305867

42.424

98.641

0.418
  dprA Neisseria gonorrhoeae MS11

38.346

100

0.416
  dprA Neisseria gonorrhoeae strain FA1090

37.845

100

0.41
  dprA Haemophilus influenzae Rd KW20

46.823

81.25

0.38

Multiple sequence alignment