Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACK2VN_RS09345 Genome accession   NZ_CP176690
Coordinates   1743600..1744838 (+) Length   412 a.a.
NCBI ID   WP_000990717.1    Uniprot ID   A0A5M9GSK5
Organism   Bacillus paranthracis strain GTVSS-022     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 1738600..1749838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2VN_RS09315 (ACK2VN_09315) yfmH 1738637..1739923 (+) 1287 WP_000411947.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ACK2VN_RS09320 (ACK2VN_09320) ymfI 1740027..1740740 (+) 714 WP_000759622.1 elongation factor P 5-aminopentanone reductase -
  ACK2VN_RS09325 (ACK2VN_09325) - 1740816..1741064 (+) 249 WP_000114454.1 DUF3243 domain-containing protein -
  ACK2VN_RS09330 (ACK2VN_09330) - 1741204..1741989 (+) 786 WP_000574107.1 DUF3388 domain-containing protein -
  ACK2VN_RS09335 (ACK2VN_09335) - 1742011..1742937 (+) 927 WP_000137489.1 helix-turn-helix domain-containing protein -
  ACK2VN_RS09340 (ACK2VN_09340) pgsA 1743001..1743579 (+) 579 WP_001052963.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACK2VN_RS09345 (ACK2VN_09345) cinA 1743600..1744838 (+) 1239 WP_000990717.1 competence/damage-inducible protein CinA Machinery gene
  ACK2VN_RS09350 (ACK2VN_09350) recA 1744983..1745591 (+) 609 Protein_1836 recombinase RecA -
  ACK2VN_RS09355 (ACK2VN_09355) - 1745918..1746340 (+) 423 Protein_1837 recombinase RecA -
  ACK2VN_RS09360 (ACK2VN_09360) rny 1746826..1748391 (+) 1566 WP_000099355.1 ribonuclease Y -
  ACK2VN_RS09365 (ACK2VN_09365) - 1748556..1749350 (+) 795 WP_001221095.1 TIGR00282 family metallophosphoesterase -
  ACK2VN_RS09370 (ACK2VN_09370) spoVS 1749499..1749759 (+) 261 WP_000404341.1 stage V sporulation protein SpoVS -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 45475.74 Da        Isoelectric Point: 5.2165

>NTDB_id=1082376 ACK2VN_RS09345 WP_000990717.1 1743600..1744838(+) (cinA) [Bacillus paranthracis strain GTVSS-022]
MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQQAIEVAEERADMLIFTGGLGPTKDDLTKET
IASSLAEELVYDEKALASISDYFKRTGREFTENNKKQALVLDGATVFANDHGMAPGMGLNKNGKVYILLPGPPKEMKPMY
VSYVEPFLRNFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHQNVHEAEKLIQHVED
LILERVGEFFYGYDQEFLHYKAIELLKKKGLTLACAESLTGGLFGNQVTENAGVSSVFKGGVICYHNDVKQHVLHVPEEV
LSTDGAVSKECARYLAENVRELLKADIGISFTGVAGPDASEHKEPGTVFVGLAIKDEPTVVFPLNLSGSRQQIRERSAKY
GFYHLYKKLEEI

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=1082376 ACK2VN_RS09345 WP_000990717.1 1743600..1744838(+) (cinA) [Bacillus paranthracis strain GTVSS-022]
ATGAACGCTGAAATTATTGCGGTTGGAACAGAATTATTACTTGGACAAATTGCAAATACGAACGCCCAGTTTTTGTCTGA
AAAGTTAGCTTCAATTGGAATTAACGTGTACTACCATACTGTAGTTGGTGATAATAACAAGCGACTGCAGCAGGCGATTG
AAGTTGCAGAAGAACGTGCGGATATGCTCATTTTCACAGGTGGATTAGGACCGACAAAAGATGATTTAACGAAGGAAACA
ATAGCGTCTAGCTTAGCGGAAGAGCTTGTATATGATGAAAAGGCATTGGCATCAATAAGCGATTACTTTAAGCGAACAGG
TCGAGAGTTCACGGAGAATAATAAAAAGCAGGCGCTCGTTTTGGATGGGGCGACTGTATTTGCAAATGATCACGGTATGG
CACCTGGTATGGGATTAAATAAGAACGGAAAAGTTTATATTTTATTACCAGGACCACCGAAAGAAATGAAGCCGATGTAT
GTAAGTTATGTGGAGCCTTTTTTACGTAACTTTACAACAGGAGAAAACATTTATTCTCGCGTGCTTCGCTTTTTCGGAAT
TGGGGAATCTCAATTAGAGGTGAAAGTTCAAGATTTAATTGATGGACAAACGAATCCGACAATCGCCCCGCTTGCCAATG
ATGGAGAAGTAACATTACGTTTAACGGCTAAACATCAAAATGTTCATGAAGCGGAGAAACTCATTCAGCATGTGGAAGAT
TTGATTTTAGAAAGAGTTGGAGAATTTTTCTACGGGTATGACCAAGAGTTTCTACATTATAAGGCGATAGAGTTATTGAA
GAAAAAAGGATTAACTTTAGCGTGTGCGGAAAGTTTAACAGGTGGTCTATTTGGTAATCAAGTAACAGAAAACGCTGGTG
TGTCTTCCGTATTTAAAGGCGGTGTCATTTGTTACCATAATGATGTGAAGCAACATGTATTACATGTACCTGAGGAAGTC
TTGTCTACTGACGGTGCAGTTAGTAAAGAATGTGCTCGTTATCTTGCTGAAAATGTTAGAGAATTATTAAAAGCGGATAT
CGGAATTAGTTTCACTGGGGTAGCAGGACCGGATGCTTCAGAACATAAAGAGCCGGGAACTGTATTTGTTGGATTGGCGA
TTAAAGATGAACCAACTGTAGTCTTTCCTCTAAATTTAAGCGGAAGTCGTCAACAAATTAGGGAACGCTCAGCAAAATAT
GGATTTTATCATTTGTATAAAAAGCTAGAAGAGATATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-408)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(179-252)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5M9GSK5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

58.981

100

0.59
  cinA Streptococcus mitis SK321

47.494

100

0.483
  cinA Streptococcus pneumoniae TIGR4

47.255

100

0.481
  cinA Streptococcus pneumoniae Rx1

46.778

100

0.476
  cinA Streptococcus pneumoniae R6

46.778

100

0.476
  cinA Streptococcus pneumoniae D39

46.539

100

0.473
  cinA Streptococcus mitis NCTC 12261

46.539

100

0.473
  cinA Streptococcus mutans UA159

45.813

98.544

0.451
  cinA Streptococcus suis isolate S10

41.534

91.748

0.381

Multiple sequence alignment