Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACK2I7_RS08030 Genome accession   NZ_CP176632
Coordinates   1625095..1626366 (-) Length   423 a.a.
NCBI ID   WP_021002200.1    Uniprot ID   A0AAP6EMF0
Organism   Streptococcus anginosus strain SFAD 40     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1620095..1631366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS07995 - 1620810..1621121 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  ACK2I7_RS08000 ruvX 1621138..1621557 (-) 420 WP_003026628.1 Holliday junction resolvase RuvX -
  ACK2I7_RS08005 - 1621557..1621823 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  ACK2I7_RS08010 - 1622104..1622661 (-) 558 WP_003026633.1 SP0191 family lipoprotein -
  ACK2I7_RS08015 - 1622765..1623334 (-) 570 WP_003026634.1 SP0191 family lipoprotein -
  ACK2I7_RS08020 spx 1623420..1623818 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  ACK2I7_RS08025 recA 1623905..1625050 (-) 1146 WP_021002199.1 recombinase RecA Machinery gene
  ACK2I7_RS08030 cinA 1625095..1626366 (-) 1272 WP_021002200.1 competence/damage-inducible protein A Machinery gene
  ACK2I7_RS08035 - 1626967..1627387 (+) 421 Protein_1558 EamA family transporter -
  ACK2I7_RS08040 - 1627490..1628068 (-) 579 WP_021002201.1 DNA-3-methyladenine glycosylase I -
  ACK2I7_RS08045 ruvA 1628079..1628669 (-) 591 WP_021002202.1 Holliday junction branch migration protein RuvA -
  ACK2I7_RS08050 - 1628831..1629340 (+) 510 WP_003026648.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45720.22 Da        Isoelectric Point: 6.2667

>NTDB_id=1081737 ACK2I7_RS08030 WP_021002200.1 1625095..1626366(-) (cinA) [Streptococcus anginosus strain SFAD 40]
MKAEIIAVGTEILTGQIVNTNARFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LAKFLNRRLVFDRMATEKLDHFFASRPDYARTPNNERQAQIVEGSTPLQNETGLAVGGVIEVGGVTYVVLPGPPSELKPM
VDNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDNQTDPTIAPYAKTGEVTLRLSTKAASQNEADIKFAHLEKKI
LAVQTFEKQHLADLFYAYGDDNSLGQTAFELLRRAGKTVTAAESLTAGLFQATLANFAGASNVFSGGFVTYSMEEKSRML
GIPLTDLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTGDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENMLQ

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1081737 ACK2I7_RS08030 WP_021002200.1 1625095..1626366(-) (cinA) [Streptococcus anginosus strain SFAD 40]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAATGCCCGATTTTTATCGGA
AAAATTAGCGAGTCTGGGTGTAGATGTGTATTTCCAAACAGCGGTTGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGAAATCGTAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAAACT
TTGGCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGACCACTTTTTCGCAAGTCGACC
GGATTATGCTCGAACACCAAATAATGAGCGGCAAGCTCAGATAGTGGAAGGATCGACTCCTCTCCAAAACGAAACCGGAC
TTGCGGTGGGAGGCGTGATTGAAGTCGGTGGTGTGACTTATGTTGTTCTCCCCGGACCGCCTAGTGAATTAAAGCCTATG
GTAGATAATGAGCTGGTTCCGCTGTTAGCAACTGGTCAAAAATTGTATTCAAGAGTCTTGCGATTCTTTGGTATCGGTGA
AAGTCAATTAGTAACCCTTTTAGGAGATTTAATTGATAATCAGACCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACCAAGGCTGCTAGTCAAAATGAAGCAGATATTAAGTTTGCCCATTTAGAAAAGAAAATT
TTAGCTGTACAGACTTTTGAGAAACAACATTTAGCAGATCTTTTCTATGCTTATGGAGATGATAATTCTCTGGGACAAAC
AGCTTTTGAACTGTTGAGAAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGGCAAACTTTGCTGGAGCCTCCAATGTTTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GGCATTCCCTTGACAGACTTAGAAAAGCATGGGGTAGTTTCAGCTTTTACAGCGGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGTTTAGCAACCACAGGGGATGTTCAGTCTATTAAGGTTAATATTGCCGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTACGAAAAACTTTATTAAAAAACGAAAATATGCTACAATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.794

98.818

0.759
  cinA Streptococcus mitis NCTC 12261

75.837

98.818

0.749
  cinA Streptococcus pneumoniae TIGR4

75.598

98.818

0.747
  cinA Streptococcus pneumoniae Rx1

75.598

98.818

0.747
  cinA Streptococcus pneumoniae R6

75.598

98.818

0.747
  cinA Streptococcus pneumoniae D39

75.359

98.818

0.745
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus suis isolate S10

55.529

98.345

0.546
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

98.818

0.454

Multiple sequence alignment