Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACKWPP_RS00390 Genome accession   NZ_CP176418
Coordinates   65652..66833 (+) Length   393 a.a.
NCBI ID   WP_044681379.1    Uniprot ID   -
Organism   Streptococcus suis strain KKAHC02     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 60652..71833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS00375 (ACKWPP_00375) mutL 62226..64163 (+) 1938 WP_024402111.1 DNA mismatch repair endonuclease MutL -
  ACKWPP_RS00380 (ACKWPP_00380) ruvA 64202..64792 (+) 591 WP_004194470.1 Holliday junction branch migration protein RuvA -
  ACKWPP_RS00385 (ACKWPP_00385) - 65046..65615 (+) 570 WP_024402110.1 DNA-3-methyladenine glycosylase I -
  ACKWPP_RS00390 (ACKWPP_00390) cinA 65652..66833 (+) 1182 WP_044681379.1 competence/damage-inducible protein A Machinery gene
  ACKWPP_RS00395 (ACKWPP_00395) recA 66885..68036 (+) 1152 WP_044679554.1 recombinase RecA Machinery gene
  ACKWPP_RS00400 (ACKWPP_00400) spx 68272..68670 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  ACKWPP_RS00405 (ACKWPP_00405) - 68770..69036 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  ACKWPP_RS00410 (ACKWPP_00410) ruvX 69036..69455 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  ACKWPP_RS00415 (ACKWPP_00415) - 69467..69787 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  ACKWPP_RS00420 (ACKWPP_00420) - 69914..71459 (+) 1546 Protein_63 IS1182 family transposase -
  ACKWPP_RS00425 (ACKWPP_00425) - 71663..71785 (+) 123 WP_257571720.1 hypothetical protein -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42917.73 Da        Isoelectric Point: 4.3708

>NTDB_id=1080040 ACKWPP_RS00390 WP_044681379.1 65652..66833(+) (cinA) [Streptococcus suis strain KKAHC02]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGVDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMVEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELNLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=1080040 ACKWPP_RS00390 WP_044681379.1 65652..66833(+) (cinA) [Streptococcus suis strain KKAHC02]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAGTTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
TTGGCAACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGGAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGGTTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAACCTGGCTT
TGGCTGATCAACCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.183

100

0.962
  cinA Streptococcus mitis SK321

56.49

100

0.598
  cinA Streptococcus pneumoniae TIGR4

56.49

100

0.598
  cinA Streptococcus pneumoniae Rx1

56.49

100

0.598
  cinA Streptococcus pneumoniae R6

56.49

100

0.598
  cinA Streptococcus mitis NCTC 12261

56.25

100

0.595
  cinA Streptococcus pneumoniae D39

56.25

100

0.595
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Bacillus subtilis subsp. subtilis str. 168

41.432

99.491

0.412

Multiple sequence alignment