Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACIUM5_RS04260 Genome accession   NZ_CP173696
Coordinates   890149..891390 (+) Length   413 a.a.
NCBI ID   WP_014569352.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus GG strain MRD080     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 882233..931120 890149..891390 within 0


Gene organization within MGE regions


Location: 882233..931120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIUM5_RS04230 - 882731..885031 (+) 2301 WP_014569347.1 DNA translocase FtsK -
  ACIUM5_RS04235 yfmF 885040..886302 (+) 1263 WP_014569348.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  ACIUM5_RS04240 yfmH 886299..887591 (+) 1293 WP_014569349.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ACIUM5_RS04245 ymfI 887591..888319 (+) 729 WP_014569350.1 elongation factor P 5-aminopentanone reductase -
  ACIUM5_RS04250 - 888406..889341 (+) 936 WP_005688668.1 helix-turn-helix domain-containing protein -
  ACIUM5_RS04255 pgsA 889338..889928 (+) 591 WP_014569351.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACIUM5_RS04260 cinA 890149..891390 (+) 1242 WP_014569352.1 competence/damage-inducible protein A Machinery gene
  ACIUM5_RS04265 recA 891442..892494 (+) 1053 WP_005688187.1 recombinase RecA Machinery gene
  ACIUM5_RS04270 rny 893119..894690 (+) 1572 WP_005684479.1 ribonuclease Y -
  ACIUM5_RS04275 - 894779..895435 (-) 657 WP_029943817.1 YigZ family protein -
  ACIUM5_RS04280 - 895463..896728 (+) 1266 WP_014569356.1 DEAD/DEAH box helicase -
  ACIUM5_RS04285 - 896887..897405 (+) 519 WP_005688681.1 ComF family protein -
  ACIUM5_RS04290 hpf 897597..898154 (+) 558 WP_005684485.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACIUM5_RS04295 secA 898737..901100 (+) 2364 WP_005684487.1 preprotein translocase subunit SecA -
  ACIUM5_RS04300 prfB 901242..902358 (+) 1117 WP_154241369.1 peptide chain release factor 2 -
  ACIUM5_RS04305 ftsE 902435..903121 (+) 687 WP_005684489.1 cell division ATP-binding protein FtsE -
  ACIUM5_RS04310 ftsX 903111..903998 (+) 888 WP_005684490.1 permease-like cell division protein FtsX -
  ACIUM5_RS04315 - 904076..904213 (+) 138 WP_014569359.1 hypothetical protein -
  ACIUM5_RS04320 - 904269..905366 (+) 1098 WP_014569360.1 PDZ domain-containing protein -
  ACIUM5_RS04325 - 905363..906067 (+) 705 WP_005688690.1 response regulator transcription factor -
  ACIUM5_RS04330 pnpS 906060..907727 (+) 1668 WP_014569361.1 two-component system histidine kinase PnpS -
  ACIUM5_RS04335 - 907817..908683 (+) 867 WP_005684496.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  ACIUM5_RS04340 pstC 908831..909754 (+) 924 WP_005684497.1 phosphate ABC transporter permease subunit PstC -
  ACIUM5_RS04345 pstA 909751..910635 (+) 885 WP_005684499.1 phosphate ABC transporter permease PstA -
  ACIUM5_RS04350 pstB 910706..911524 (+) 819 WP_005713669.1 phosphate ABC transporter ATP-binding protein PstB -
  ACIUM5_RS04355 pstB 911534..912298 (+) 765 WP_005684501.1 phosphate ABC transporter ATP-binding protein PstB -
  ACIUM5_RS04360 phoU 912309..912986 (+) 678 WP_005684502.1 phosphate signaling complex protein PhoU -
  ACIUM5_RS04365 - 913240..914118 (-) 879 WP_048653158.1 IS3 family transposase -
  ACIUM5_RS04370 - 914115..914843 (-) 729 WP_014569363.1 helix-turn-helix domain-containing protein -
  ACIUM5_RS04375 liaX 915412..916902 (+) 1491 WP_014569364.1 daptomycin-sensing surface protein LiaX -
  ACIUM5_RS04380 - 916914..917174 (+) 261 WP_005688700.1 hypothetical protein -
  ACIUM5_RS04385 - 917177..917512 (+) 336 WP_005684507.1 phage holin family protein -
  ACIUM5_RS04390 hprK 917779..918738 (+) 960 WP_005684508.1 HPr(Ser) kinase/phosphatase -
  ACIUM5_RS04395 lgt 918740..919567 (+) 828 WP_014569365.1 prolipoprotein diacylglyceryl transferase -
  ACIUM5_RS04400 - 919578..920633 (+) 1056 WP_014569366.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ACIUM5_RS04405 trxB 920699..921646 (+) 948 WP_005684511.1 thioredoxin-disulfide reductase -
  ACIUM5_RS04410 - 921898..923625 (+) 1728 WP_014569367.1 phospho-sugar mutase -
  ACIUM5_RS04415 - 924085..924732 (+) 648 WP_014569368.1 YfbR-like 5'-deoxynucleotidase -
  ACIUM5_RS04420 uvrB 925003..927018 (+) 2016 WP_005688715.1 excinuclease ABC subunit UvrB -
  ACIUM5_RS04425 uvrA 927199..930093 (+) 2895 WP_014569369.1 excinuclease ABC subunit UvrA -
  ACIUM5_RS04430 - 930295..930834 (+) 540 WP_014569370.1 HdeD family acid-resistance protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44472.12 Da        Isoelectric Point: 7.2504

>NTDB_id=1073731 ACIUM5_RS04260 WP_014569352.1 890149..891390(+) (cinA) [Lacticaseibacillus rhamnosus GG strain MRD080]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=1073731 ACIUM5_RS04260 WP_014569352.1 890149..891390(+) (cinA) [Lacticaseibacillus rhamnosus GG strain MRD080]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

52.019

100

0.53
  cinA Streptococcus mitis NCTC 12261

52.019

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.544

100

0.525
  cinA Streptococcus pneumoniae R6

51.069

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.069

100

0.521
  cinA Streptococcus mutans UA159

51.442

100

0.518
  cinA Streptococcus pneumoniae D39

50.831

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

44.66

99.758

0.446
  cinA Streptococcus suis isolate S10

42.593

91.525

0.39

Multiple sequence alignment