Detailed information NTG1070501

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: ACIQTD_RS08205
• Genome accession: NZ_CP173185
• Coordinates: 1730436..1731128 (-)
• Length: 230 a.a.
• NCBI ID: WP_012898209.1
• Uniprot ID: A0AAW7IPJ0
• Organism: Lactococcus lactis subsp. lactis strain MGEL24009
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1725436..1736128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIQTD_RS08190	-	1727056..1727397 (-)	342	WP_010906046.1	P-II family nitrogen regulator	-
ACIQTD_RS08195	-	1727529..1728770 (-)	1242	WP_012898207.1	ammonium transporter	-
ACIQTD_RS08200	covS	1728952..1730427 (-)	1476	WP_017864798.1	HAMP domain-containing histidine kinase	Regulator
ACIQTD_RS08205	covR	1730436..1731128 (-)	693	WP_012898209.1	response regulator transcription factor	Regulator
ACIQTD_RS08210	-	1731284..1731814 (-)	531	WP_270249454.1	DUF177 domain-containing protein	-
ACIQTD_RS08215	-	1731945..1732190 (-)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
ACIQTD_RS08220	-	1732346..1732810 (-)	465	WP_017864799.1	hypothetical protein	-
ACIQTD_RS08225	-	1732893..1733255 (-)	363	WP_404399095.1	TIGR02328 family protein	-
ACIQTD_RS08230	-	1733604..1733735 (-)	132	WP_021722678.1	hypothetical protein	-
ACIQTD_RS08235	-	1733739..1734236 (-)	498	WP_226898137.1	CHAP domain-containing protein	-
ACIQTD_RS08240	-	1734330..1735166 (-)	837	WP_023164354.1	metallophosphoesterase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26670.33 Da
• Isoelectric Point: 5.1273

>NTDB_id=1070501 ACIQTD_RS08205 WP_012898209.1 1730436..1731128(-) (covR) [Lactococcus lactis subsp. lactis strain MGEL24009]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEASSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide

• Length: 693 bp

>NTDB_id=1070501 ACIQTD_RS08205 WP_012898209.1 1730436..1731128(-) (covR) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATGCGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAAGTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACAGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (153-226)

• Response regulator receiver domain (Response_reg) (6-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	99.565	100	0.996
covR	Streptococcus salivarius strain HSISS4	68.421	99.13	0.678
vicR	Streptococcus mutans UA159	45.887	100	0.461
micA	Streptococcus pneumoniae Cp1015	43.478	100	0.435
ciaR	Streptococcus mutans UA159	37.611	98.261	0.37
ciaR	Streptococcus pneumoniae Rx1	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae D39	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae R6	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae TIGR4	36.726	98.261	0.361