Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ACIQTD_RS08200 Genome accession   NZ_CP173185
Coordinates   1728952..1730427 (-) Length   491 a.a.
NCBI ID   WP_017864798.1    Uniprot ID   A0AAE4T2B5
Organism   Lactococcus lactis subsp. lactis strain MGEL24009     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1723952..1735427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIQTD_RS08185 murD 1725212..1726564 (-) 1353 WP_058217271.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  ACIQTD_RS08190 - 1727056..1727397 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  ACIQTD_RS08195 - 1727529..1728770 (-) 1242 WP_012898207.1 ammonium transporter -
  ACIQTD_RS08200 covS 1728952..1730427 (-) 1476 WP_017864798.1 HAMP domain-containing histidine kinase Regulator
  ACIQTD_RS08205 covR 1730436..1731128 (-) 693 WP_012898209.1 response regulator transcription factor Regulator
  ACIQTD_RS08210 - 1731284..1731814 (-) 531 WP_270249454.1 DUF177 domain-containing protein -
  ACIQTD_RS08215 - 1731945..1732190 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  ACIQTD_RS08220 - 1732346..1732810 (-) 465 WP_017864799.1 hypothetical protein -
  ACIQTD_RS08225 - 1732893..1733255 (-) 363 WP_404399095.1 TIGR02328 family protein -
  ACIQTD_RS08230 - 1733604..1733735 (-) 132 WP_021722678.1 hypothetical protein -
  ACIQTD_RS08235 - 1733739..1734236 (-) 498 WP_226898137.1 CHAP domain-containing protein -
  ACIQTD_RS08240 - 1734330..1735166 (-) 837 WP_023164354.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56183.03 Da        Isoelectric Point: 4.8253

>NTDB_id=1070500 ACIQTD_RS08200 WP_017864798.1 1728952..1730427(-) (covS) [Lactococcus lactis subsp. lactis strain MGEL24009]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLTVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=1070500 ACIQTD_RS08200 WP_017864798.1 1728952..1730427(-) (covS) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGACTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.796

100

0.998

Multiple sequence alignment