Detailed information NTG1070497

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ACIQTD_RS06105
• Genome accession: NZ_CP173185
• Coordinates: 1270804..1271652 (+)
• Length: 282 a.a.
• NCBI ID: WP_404399030.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain MGEL24009
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1265804..1276652

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIQTD_RS06080	ilvN	1266558..1267034 (+)	477	WP_010905839.1	acetolactate synthase small subunit	-
ACIQTD_RS06085	ilvC	1267080..1268102 (+)	1023	WP_237579828.1	ketol-acid reductoisomerase	-
ACIQTD_RS06090	ilvA	1268158..1269408 (+)	1251	WP_015426407.1	threonine ammonia-lyase IlvA	-
ACIQTD_RS06095	budA	1269527..1270237 (+)	711	WP_003131140.1	acetolactate decarboxylase	-
ACIQTD_RS06100	-	1270278..1270658 (+)	381	WP_015426409.1	RidA family protein	-
ACIQTD_RS06105	dprA	1270804..1271652 (+)	849	WP_404399030.1	DNA-processing protein DprA	Machinery gene
ACIQTD_RS06110	topA	1271914..1274046 (+)	2133	WP_270250810.1	type I DNA topoisomerase	-
ACIQTD_RS06115	trmFO	1274118..1275461 (+)	1344	WP_003131150.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACIQTD_RS06120	xerS	1275506..1276576 (-)	1071	WP_003131037.1	tyrosine recombinase XerS	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 32029.04 Da
• Isoelectric Point: 9.5333

>NTDB_id=1070497 ACIQTD_RS06105 WP_404399030.1 1270804..1271652(+) (dprA) [Lactococcus lactis subsp. lactis strain MGEL24009]
MITNFDLYRWKKAGMTNLGVNKLLKFFHRYDKKISLRQMGQVAQLKSIPNFIEQYKNQDVSKLREDYKIYPSFSLLDEIY
PERLKEIYNPPVLLFYQGDIRLLKTPKLAFVGSRQASSQGIKAVQKIVTELNQNFTIVSGLAKGIDTASHLSAIKNKIPT
IAVIGTGLDIFSPLENRKIQEYLAKNQLILSEYSVGEKPLRYHFPERNRIIAGLSHGVVVIEAKLRSGSLITCERALEEG
RDIFAVPGNIADGFSDGCNHLIQQGAKLIYQAQDILEEYLYD

Nucleotide

• Length: 849 bp

>NTDB_id=1070497 ACIQTD_RS06105 WP_404399030.1 1270804..1271652(+) (dprA) [Lactococcus lactis subsp. lactis strain MGEL24009]
ATGATAACAAATTTTGATTTATATCGTTGGAAAAAAGCTGGCATGACCAATTTAGGAGTAAATAAACTTTTAAAATTTTT
TCATAGATATGATAAAAAAATAAGTTTAAGACAAATGGGACAAGTAGCACAACTTAAATCAATTCCCAACTTTATTGAAC
AATATAAAAATCAAGACGTAAGTAAACTGAGAGAAGATTATAAAATATACCCATCATTTTCTCTTCTTGATGAAATTTAT
CCCGAAAGGCTCAAGGAAATTTACAATCCACCGGTTCTATTATTTTATCAAGGAGATATAAGACTCTTAAAAACTCCTAA
ATTAGCTTTTGTTGGTAGTCGACAAGCAAGCTCACAAGGAATTAAAGCCGTTCAAAAAATTGTGACAGAGTTGAACCAAA
ATTTTACGATTGTCAGCGGACTCGCTAAAGGAATAGATACAGCAAGTCATCTTTCTGCCATTAAAAATAAAATCCCTACA
ATTGCAGTTATCGGTACAGGCTTAGATATCTTTTCTCCTTTAGAAAATCGAAAAATTCAAGAATATCTTGCTAAAAACCA
ACTCATACTATCAGAATATTCAGTCGGAGAAAAACCACTTCGCTATCATTTTCCTGAACGCAATCGTATCATTGCAGGAC
TTTCACATGGTGTAGTAGTGATAGAAGCAAAGTTACGAAGTGGTAGTTTAATTACTTGTGAGCGCGCTCTGGAAGAAGGA
AGAGATATTTTCGCTGTACCAGGAAACATAGCAGATGGATTTTCAGATGGCTGTAATCATCTCATACAACAAGGAGCAAA
ATTAATCTATCAAGCCCAAGATATCTTAGAAGAATATTTGTATGATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (76-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	86.879	100	0.869
dprA	Streptococcus mutans UA159	59.353	98.582	0.585
dprA/cilB/dalA	Streptococcus mitis SK321	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	53.214	99.291	0.528
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	53.214	99.291	0.528
dprA/cilB/dalA	Streptococcus pneumoniae R6	53.214	99.291	0.528
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	53.214	99.291	0.528
dprA/cilB/dalA	Streptococcus pneumoniae D39	53.214	99.291	0.528
dprA	Legionella pneumophila strain ERS1305867	38.828	96.809	0.376
dprA	Haemophilus influenzae Rd KW20	38.519	95.745	0.369
dprA	Latilactobacillus sakei subsp. sakei 23K	40	90.426	0.362