Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACDQ48_RS04650 Genome accession   NZ_CP173118
Coordinates   971594..972835 (+) Length   413 a.a.
NCBI ID   WP_014569352.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus strain B3421     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 963678..1012565 971594..972835 within 0


Gene organization within MGE regions


Location: 963678..1012565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACDQ48_RS04620 - 964176..966476 (+) 2301 WP_014569347.1 DNA translocase FtsK -
  ACDQ48_RS04625 yfmF 966485..967747 (+) 1263 WP_014569348.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  ACDQ48_RS04630 yfmH 967744..969036 (+) 1293 WP_014569349.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ACDQ48_RS04635 ymfI 969036..969764 (+) 729 WP_014569350.1 elongation factor P 5-aminopentanone reductase -
  ACDQ48_RS04640 - 969851..970786 (+) 936 WP_005688668.1 helix-turn-helix domain-containing protein -
  ACDQ48_RS04645 pgsA 970783..971373 (+) 591 WP_014569351.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACDQ48_RS04650 cinA 971594..972835 (+) 1242 WP_014569352.1 competence/damage-inducible protein A Machinery gene
  ACDQ48_RS04655 recA 972887..973939 (+) 1053 WP_005688187.1 recombinase RecA Machinery gene
  ACDQ48_RS04660 rny 974564..976135 (+) 1572 WP_005684479.1 ribonuclease Y -
  ACDQ48_RS04665 - 976224..976880 (-) 657 WP_029943817.1 YigZ family protein -
  ACDQ48_RS04670 - 976908..978173 (+) 1266 WP_014569356.1 DEAD/DEAH box helicase -
  ACDQ48_RS04675 - 978332..978850 (+) 519 WP_005688681.1 ComF family protein -
  ACDQ48_RS04680 hpf 979042..979599 (+) 558 WP_005684485.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACDQ48_RS04685 secA 980182..982545 (+) 2364 WP_005684487.1 preprotein translocase subunit SecA -
  ACDQ48_RS04690 prfB 982687..983803 (+) 1117 WP_154241369.1 peptide chain release factor 2 -
  ACDQ48_RS04695 ftsE 983880..984566 (+) 687 WP_005684489.1 cell division ATP-binding protein FtsE -
  ACDQ48_RS04700 ftsX 984556..985443 (+) 888 WP_005684490.1 permease-like cell division protein FtsX -
  ACDQ48_RS04705 - 985521..985658 (+) 138 WP_014569359.1 hypothetical protein -
  ACDQ48_RS04710 - 985714..986811 (+) 1098 WP_014569360.1 PDZ domain-containing protein -
  ACDQ48_RS04715 - 986808..987512 (+) 705 WP_005688690.1 response regulator transcription factor -
  ACDQ48_RS04720 pnpS 987505..989172 (+) 1668 WP_014569361.1 two-component system histidine kinase PnpS -
  ACDQ48_RS04725 - 989262..990128 (+) 867 WP_005684496.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  ACDQ48_RS04730 pstC 990276..991199 (+) 924 WP_005684497.1 phosphate ABC transporter permease subunit PstC -
  ACDQ48_RS04735 pstA 991196..992080 (+) 885 WP_005684499.1 phosphate ABC transporter permease PstA -
  ACDQ48_RS04740 pstB 992151..992969 (+) 819 WP_005713669.1 phosphate ABC transporter ATP-binding protein PstB -
  ACDQ48_RS04745 pstB 992979..993743 (+) 765 WP_005684501.1 phosphate ABC transporter ATP-binding protein PstB -
  ACDQ48_RS04750 phoU 993754..994431 (+) 678 WP_005684502.1 phosphate signaling complex protein PhoU -
  ACDQ48_RS04755 - 994685..995563 (-) 879 WP_048653158.1 IS3 family transposase -
  ACDQ48_RS04760 - 995560..996288 (-) 729 WP_014569363.1 helix-turn-helix domain-containing protein -
  ACDQ48_RS04765 liaX 996857..998347 (+) 1491 WP_014569364.1 daptomycin-sensing surface protein LiaX -
  ACDQ48_RS04770 - 998359..998619 (+) 261 WP_005688700.1 hypothetical protein -
  ACDQ48_RS04775 - 998622..998957 (+) 336 WP_005684507.1 phage holin family protein -
  ACDQ48_RS04780 hprK 999224..1000183 (+) 960 WP_005684508.1 HPr(Ser) kinase/phosphatase -
  ACDQ48_RS04785 lgt 1000185..1001012 (+) 828 WP_014569365.1 prolipoprotein diacylglyceryl transferase -
  ACDQ48_RS04790 - 1001023..1002078 (+) 1056 WP_014569366.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ACDQ48_RS04795 trxB 1002144..1003091 (+) 948 WP_005684511.1 thioredoxin-disulfide reductase -
  ACDQ48_RS04800 - 1003343..1005070 (+) 1728 WP_014569367.1 phospho-sugar mutase -
  ACDQ48_RS04805 - 1005530..1006177 (+) 648 WP_014569368.1 YfbR-like 5'-deoxynucleotidase -
  ACDQ48_RS04810 uvrB 1006448..1008463 (+) 2016 WP_005688715.1 excinuclease ABC subunit UvrB -
  ACDQ48_RS04815 uvrA 1008644..1011538 (+) 2895 WP_014569369.1 excinuclease ABC subunit UvrA -
  ACDQ48_RS04820 - 1011740..1012279 (+) 540 WP_014569370.1 HdeD family acid-resistance protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44472.12 Da        Isoelectric Point: 7.2504

>NTDB_id=1070283 ACDQ48_RS04650 WP_014569352.1 971594..972835(+) (cinA) [Lacticaseibacillus rhamnosus strain B3421]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=1070283 ACDQ48_RS04650 WP_014569352.1 971594..972835(+) (cinA) [Lacticaseibacillus rhamnosus strain B3421]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

52.019

100

0.53
  cinA Streptococcus mitis NCTC 12261

52.019

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.544

100

0.525
  cinA Streptococcus pneumoniae R6

51.069

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.069

100

0.521
  cinA Streptococcus mutans UA159

51.442

100

0.518
  cinA Streptococcus pneumoniae D39

50.831

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

44.66

99.758

0.446
  cinA Streptococcus suis isolate S10

42.593

91.525

0.39

Multiple sequence alignment