Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACF1RT_RS09960 Genome accession   NZ_CP172847
Coordinates   1998770..2000026 (-) Length   418 a.a.
NCBI ID   WP_002266115.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1993770..2005026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS09915 (ACF1RT_09915) - 1993963..1994262 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  ACF1RT_RS09920 (ACF1RT_09920) ruvX 1994343..1994762 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  ACF1RT_RS09925 (ACF1RT_09925) - 1994759..1995028 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  ACF1RT_RS09930 (ACF1RT_09930) brsR 1995196..1995630 (+) 435 WP_002266979.1 bacteriocin genes transcriptional regulator BrsR Regulator
  ACF1RT_RS09935 (ACF1RT_09935) brsM 1995643..1996089 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  ACF1RT_RS09940 (ACF1RT_09940) - 1996080..1996292 (-) 213 WP_002262389.1 hypothetical protein -
  ACF1RT_RS09945 (ACF1RT_09945) - 1996419..1996844 (-) 426 WP_002269684.1 hypothetical protein -
  ACF1RT_RS09950 (ACF1RT_09950) spx 1997096..1997494 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  ACF1RT_RS09955 (ACF1RT_09955) recA 1997579..1998730 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  ACF1RT_RS09960 (ACF1RT_09960) cinA 1998770..2000026 (-) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  ACF1RT_RS09965 (ACF1RT_09965) - 2000175..2000735 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  ACF1RT_RS09970 (ACF1RT_09970) ruvA 2000817..2001410 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  ACF1RT_RS09975 (ACF1RT_09975) mutL 2001593..2003548 (-) 1956 WP_226711215.1 DNA mismatch repair endonuclease MutL -
  ACF1RT_RS09980 (ACF1RT_09980) - 2003773..2004051 (+) 279 Protein_1914 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45718.51 Da        Isoelectric Point: 6.2714

>NTDB_id=1069121 ACF1RT_RS09960 WP_002266115.1 1998770..2000026(-) (cinA) [Streptococcus mutans strain DPC6143]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1069121 ACF1RT_RS09960 WP_002266115.1 1998770..2000026(-) (cinA) [Streptococcus mutans strain DPC6143]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGTT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.761

100

0.998
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452

Multiple sequence alignment