Detailed information NTG0106581

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: AABJ45_RS04620
• Genome accession: NZ_AP028611
• Coordinates: 910702..911352 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387346.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep6
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 905702..916352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS04590 (TKY121527_09110)	-	906209..906424 (+)	216	WP_001232082.1	YozE family protein	-
AABJ45_RS04595 (TKY121527_09120)	-	906510..907478 (+)	969	WP_000658183.1	PhoH family protein	-
AABJ45_RS04600 (TKY121527_09130)	-	907671..908171 (+)	501	WP_000566985.1	GNAT family N-acetyltransferase	-
AABJ45_RS04605 (TKY121527_09140)	-	908174..908500 (+)	327	Protein_908	TfoX/Sxy family protein	-
AABJ45_RS04610 (TKY121527_09160)	ald	908801..909888 (-)	1088	Protein_909	alanine dehydrogenase	-
AABJ45_RS04615 (TKY121527_09170)	-	910065..910634 (+)	570	WP_000443745.1	GNAT family N-acetyltransferase	-
AABJ45_RS04620 (TKY121527_09180)	comEA/celA/cilE	910702..911352 (+)	651	WP_000387346.1	helix-hairpin-helix domain-containing protein	Machinery gene
AABJ45_RS04625 (TKY121527_09190)	comEC/celB	911336..913576 (+)	2241	WP_000942416.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AABJ45_RS04630	-	913725..913942 (+)	218	Protein_913	hypothetical protein	-
AABJ45_RS04635 (TKY121527_09200)	-	913975..914562 (+)	588	WP_000939883.1	ABC transporter ATP-binding protein	-
AABJ45_RS04640 (TKY121527_09210)	-	914566..915747 (+)	1182	WP_000655941.1	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23109.37 Da
• Isoelectric Point: 6.0661

>NTDB_id=106581 AABJ45_RS04620 WP_000387346.1 910702..911352(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain Sep6]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTGKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=106581 AABJ45_RS04620 WP_000387346.1 910702..911352(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain Sep6]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGGAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.611	100	0.986
comEA/celA/cilE	Streptococcus pneumoniae Rx1	96.759	100	0.968
comEA/celA/cilE	Streptococcus pneumoniae D39	96.759	100	0.968
comEA/celA/cilE	Streptococcus pneumoniae R6	96.759	100	0.968
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37
comEA	Bacillus subtilis subsp. subtilis str. 168	41.053	87.963	0.361