Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AABA19_RS02575 Genome accession   NZ_AP028609
Coordinates   503512..504525 (-) Length   337 a.a.
NCBI ID   WP_307772067.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 498512..509525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS02545 (TKY121806_04980) - 498787..499125 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  AABA19_RS02550 (TKY121806_04990) comE/blpR 499130..499867 (+) 738 WP_001219120.1 response regulator transcription factor Regulator
  AABA19_RS02555 (TKY121806_05000) - 499881..501221 (+) 1341 WP_001017646.1 sensor histidine kinase -
  AABA19_RS02560 (TKY121806_05010) blpC 501292..501420 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  AABA19_RS02565 (TKY121806_05020) - 501477..502838 (-) 1362 WP_338171499.1 bacteriocin secretion accessory protein -
  AABA19_RS02570 (TKY121806_05030) comA/nlmT 502849..503496 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  AABA19_RS02575 (TKY121806_05040) comA/nlmT 503512..504525 (-) 1014 WP_307772067.1 ABC transporter transmembrane domain-containing protein Regulator
  AABA19_RS02580 (TKY121806_05050) comA/nlmT 504419..505006 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  AABA19_RS02585 (TKY121806_05060) - 505287..505520 (+) 234 WP_050315299.1 hypothetical protein -
  AABA19_RS02590 (TKY121806_05070) - 505552..506241 (+) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  AABA19_RS02595 (TKY121806_05080) blpZ 506283..506516 (+) 234 WP_000276498.1 immunity protein BlpZ -
  AABA19_RS02600 - 506667..507278 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -
  AABA19_RS02605 (TKY121806_05090) ccrZ 507439..508233 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -
  AABA19_RS02610 (TKY121806_05100) trmB 508230..508865 (+) 636 WP_001266083.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  AABA19_RS02615 (TKY121806_05110) rimP 508991..509470 (+) 480 WP_001810863.1 ribosome maturation factor RimP -

Sequence

Protein


Download         Length: 337 a.a.        Molecular weight: 38280.73 Da        Isoelectric Point: 5.1196

>NTDB_id=106418 AABA19_RS02575 WP_307772067.1 503512..504525(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep4]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFG

Nucleotide


Download         Length: 1014 bp        

>NTDB_id=106418 AABA19_RS02575 WP_307772067.1 503512..504525(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep4]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTAGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGATGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.997

100

0.73
  comA Streptococcus gordonii str. Challis substr. CH1

67.16

100

0.674
  comA Streptococcus mitis NCTC 12261

66.766

100

0.668
  comA Streptococcus pneumoniae Rx1

66.469

100

0.665
  comA Streptococcus pneumoniae D39

66.469

100

0.665
  comA Streptococcus pneumoniae R6

66.469

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.172

100

0.662
  comA Streptococcus mitis SK321

66.172

100

0.662

Multiple sequence alignment