Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AABA19_RS02570 Genome accession   NZ_AP028609
Coordinates   502849..503496 (-) Length   215 a.a.
NCBI ID   WP_078064020.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 497849..508496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS02540 (TKY121806_04970) - 498182..498511 (-) 330 WP_000132575.1 hypothetical protein -
  AABA19_RS02545 (TKY121806_04980) - 498787..499125 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  AABA19_RS02550 (TKY121806_04990) comE/blpR 499130..499867 (+) 738 WP_001219120.1 response regulator transcription factor Regulator
  AABA19_RS02555 (TKY121806_05000) - 499881..501221 (+) 1341 WP_001017646.1 sensor histidine kinase -
  AABA19_RS02560 (TKY121806_05010) blpC 501292..501420 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  AABA19_RS02565 (TKY121806_05020) - 501477..502838 (-) 1362 WP_338171499.1 bacteriocin secretion accessory protein -
  AABA19_RS02570 (TKY121806_05030) comA/nlmT 502849..503496 (-) 648 WP_078064020.1 ATP-binding cassette domain-containing protein Regulator
  AABA19_RS02575 (TKY121806_05040) comA/nlmT 503512..504525 (-) 1014 WP_307772067.1 ABC transporter transmembrane domain-containing protein Regulator
  AABA19_RS02580 (TKY121806_05050) comA/nlmT 504419..505006 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  AABA19_RS02585 (TKY121806_05060) - 505287..505520 (+) 234 WP_050315299.1 hypothetical protein -
  AABA19_RS02590 (TKY121806_05070) - 505552..506241 (+) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  AABA19_RS02595 (TKY121806_05080) blpZ 506283..506516 (+) 234 WP_000276498.1 immunity protein BlpZ -
  AABA19_RS02600 - 506667..507278 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -
  AABA19_RS02605 (TKY121806_05090) ccrZ 507439..508233 (+) 795 WP_000363002.1 cell cycle regulator CcrZ -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 23976.78 Da        Isoelectric Point: 9.2946

>NTDB_id=106417 AABA19_RS02570 WP_078064020.1 502849..503496(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep4]
MNLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGG
NHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDN
LMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 648 bp        

>NTDB_id=106417 AABA19_RS02570 WP_078064020.1 502849..503496(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep4]
ATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAAT
GATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCT
TGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGT
AATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTAT
GGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTT
TAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAAT
CTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGT
TCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCA
ATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.495

99.535

0.712
  comA Streptococcus mitis NCTC 12261

66.977

100

0.67
  comA Streptococcus pneumoniae Rx1

66.512

100

0.665
  comA Streptococcus pneumoniae D39

66.512

100

0.665
  comA Streptococcus pneumoniae R6

66.512

100

0.665
  comA Streptococcus mitis SK321

66.512

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.047

100

0.66
  comA Streptococcus gordonii str. Challis substr. CH1

66.047

100

0.66
  rcrQ Streptococcus mutans UA159

38.679

98.605

0.381

Multiple sequence alignment