Detailed information NTG0106419

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: AABA19_RS02580
• Genome accession: NZ_AP028609
• Coordinates: 504419..505006 (-)
• Length: 195 a.a.
• NCBI ID: WP_000205166.1
• Uniprot ID: Q9ETN5
• Organism: Streptococcus pneumoniae strain Sep4
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 499419..510006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA19_RS02555 (TKY121806_05000)	-	499881..501221 (+)	1341	WP_001017646.1	sensor histidine kinase	-
AABA19_RS02560 (TKY121806_05010)	blpC	501292..501420 (-)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
AABA19_RS02565 (TKY121806_05020)	-	501477..502838 (-)	1362	WP_338171499.1	bacteriocin secretion accessory protein	-
AABA19_RS02570 (TKY121806_05030)	comA/nlmT	502849..503496 (-)	648	WP_078064020.1	ATP-binding cassette domain-containing protein	Regulator
AABA19_RS02575 (TKY121806_05040)	comA/nlmT	503512..504525 (-)	1014	WP_307772067.1	ABC transporter transmembrane domain-containing protein	Regulator
AABA19_RS02580 (TKY121806_05050)	comA/nlmT	504419..505006 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
AABA19_RS02585 (TKY121806_05060)	-	505287..505520 (+)	234	WP_050315299.1	hypothetical protein	-
AABA19_RS02590 (TKY121806_05070)	-	505552..506241 (+)	690	WP_000760523.1	CPBP family intramembrane glutamic endopeptidase	-
AABA19_RS02595 (TKY121806_05080)	blpZ	506283..506516 (+)	234	WP_000276498.1	immunity protein BlpZ	-
AABA19_RS02600	-	506667..507278 (+)	612	WP_000394036.1	CPBP family intramembrane glutamic endopeptidase	-
AABA19_RS02605 (TKY121806_05090)	ccrZ	507439..508233 (+)	795	WP_000363002.1	cell cycle regulator CcrZ	-
AABA19_RS02610 (TKY121806_05100)	trmB	508230..508865 (+)	636	WP_001266083.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
AABA19_RS02615 (TKY121806_05110)	rimP	508991..509470 (+)	480	WP_001810863.1	ribosome maturation factor RimP	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22270.71 Da
• Isoelectric Point: 9.6188

>NTDB_id=106419 AABA19_RS02580 WP_000205166.1 504419..505006(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep4]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=106419 AABA19_RS02580 WP_000205166.1 504419..505006(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep4]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: Q9ETN5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.89	93.333	0.559
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497