Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACG3JH_RS08185 Genome accession   NZ_CP171731
Coordinates   1583896..1585167 (+) Length   423 a.a.
NCBI ID   WP_003103228.1    Uniprot ID   A0A0E2UCS4
Organism   Streptococcus parauberis strain DB-M1     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1566370..1594591 1583896..1585167 within 0


Gene organization within MGE regions


Location: 1566370..1594591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JH_RS08070 (ACG3JH_08070) - 1566370..1566984 (-) 615 WP_013794516.1 CadD family cadmium resistance transporter -
  ACG3JH_RS08075 (ACG3JH_08075) - 1567669..1568241 (+) 573 WP_013794515.1 Ltp family lipoprotein -
  ACG3JH_RS08080 (ACG3JH_08080) - 1568612..1568905 (-) 294 WP_041828671.1 hypothetical protein -
  ACG3JH_RS08085 (ACG3JH_08085) - 1569180..1569467 (-) 288 WP_013794514.1 DUF4298 domain-containing protein -
  ACG3JH_RS08090 (ACG3JH_08090) - 1569539..1569685 (-) 147 WP_165848363.1 hypothetical protein -
  ACG3JH_RS08095 (ACG3JH_08095) - 1570275..1570697 (-) 423 WP_013794513.1 DUF1492 domain-containing protein -
  ACG3JH_RS08100 (ACG3JH_08100) - 1571388..1571738 (-) 351 WP_013794512.1 hypothetical protein -
  ACG3JH_RS08105 (ACG3JH_08105) - 1571740..1572327 (-) 588 WP_013794511.1 hypothetical protein -
  ACG3JH_RS08110 (ACG3JH_08110) - 1572471..1572662 (-) 192 WP_121823783.1 hypothetical protein -
  ACG3JH_RS08115 (ACG3JH_08115) - 1572671..1572886 (-) 216 WP_041828668.1 hypothetical protein -
  ACG3JH_RS08120 (ACG3JH_08120) - 1572876..1573190 (-) 315 WP_013794510.1 hypothetical protein -
  ACG3JH_RS08125 (ACG3JH_08125) - 1573473..1575032 (-) 1560 WP_013794509.1 hypothetical protein -
  ACG3JH_RS08130 (ACG3JH_08130) - 1575175..1575693 (-) 519 WP_394714021.1 hypothetical protein -
  ACG3JH_RS08135 (ACG3JH_08135) - 1575703..1575975 (-) 273 WP_041828666.1 hypothetical protein -
  ACG3JH_RS08140 (ACG3JH_08140) - 1575988..1576221 (-) 234 WP_041828664.1 hypothetical protein -
  ACG3JH_RS08145 (ACG3JH_08145) - 1576209..1576442 (-) 234 WP_041828663.1 hypothetical protein -
  ACG3JH_RS08150 (ACG3JH_08150) - 1576656..1576841 (-) 186 WP_041828660.1 hypothetical protein -
  ACG3JH_RS08155 (ACG3JH_08155) - 1576996..1577823 (+) 828 WP_013794507.1 helix-turn-helix domain-containing protein -
  ACG3JH_RS08160 (ACG3JH_08160) - 1577905..1579050 (+) 1146 WP_045407338.1 site-specific integrase -
  ACG3JH_RS08165 (ACG3JH_08165) mutL 1579147..1581123 (+) 1977 WP_041828658.1 DNA mismatch repair endonuclease MutL -
  ACG3JH_RS08170 (ACG3JH_08170) - 1581134..1582357 (+) 1224 WP_003103803.1 MFS transporter -
  ACG3JH_RS08175 (ACG3JH_08175) ruvA 1582359..1582952 (+) 594 WP_003107862.1 Holliday junction branch migration protein RuvA -
  ACG3JH_RS08180 (ACG3JH_08180) - 1582956..1583507 (+) 552 WP_096633379.1 DNA-3-methyladenine glycosylase I -
  ACG3JH_RS08185 (ACG3JH_08185) cinA 1583896..1585167 (+) 1272 WP_003103228.1 competence/damage-inducible protein A Machinery gene
  ACG3JH_RS08190 (ACG3JH_08190) recA 1585247..1586386 (+) 1140 WP_003102546.1 recombinase RecA Machinery gene
  ACG3JH_RS08195 (ACG3JH_08195) spx 1586740..1587138 (+) 399 WP_003104943.1 transcriptional regulator Spx -
  ACG3JH_RS08200 (ACG3JH_08200) - 1587252..1587521 (+) 270 WP_003104158.1 IreB family regulatory phosphoprotein -
  ACG3JH_RS08205 (ACG3JH_08205) ruvX 1587518..1587937 (+) 420 WP_003105581.1 Holliday junction resolvase RuvX -
  ACG3JH_RS08210 (ACG3JH_08210) - 1587948..1588265 (+) 318 WP_003104776.1 DUF1292 domain-containing protein -
  ACG3JH_RS08215 (ACG3JH_08215) - 1588414..1589973 (+) 1560 WP_045407342.1 membrane protein -
  ACG3JH_RS08220 (ACG3JH_08220) nrdD 1590073..1592262 (+) 2190 WP_013794500.1 anaerobic ribonucleoside-triphosphate reductase -
  ACG3JH_RS08225 (ACG3JH_08225) - 1592352..1592501 (+) 150 WP_003108936.1 hypothetical protein -
  ACG3JH_RS08230 (ACG3JH_08230) - 1592525..1593487 (+) 963 WP_013794498.1 Gfo/Idh/MocA family protein -
  ACG3JH_RS08235 (ACG3JH_08235) - 1593468..1593962 (+) 495 WP_003108940.1 GNAT family N-acetyltransferase -
  ACG3JH_RS08240 (ACG3JH_08240) nrdG 1593977..1594591 (+) 615 WP_003104313.1 anaerobic ribonucleoside-triphosphate reductase activating protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46101.75 Da        Isoelectric Point: 4.8894

>NTDB_id=1063742 ACG3JH_RS08185 WP_003103228.1 1583896..1585167(+) (cinA) [Streptococcus parauberis strain DB-M1]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAEIGVDVYYHTAVGDNEIRLLNILEVASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGLSLVFDREASQKLDQFFSSRSESSRTPNNERQAQLIEGSKPIQNITGLAVGGLIEKAGVTYVVLPGPPSELKPM
VNQYLLPLLLNEETKLYSRVLRFFGIGESQLVTILADLIANQSDPTIAPYAKIGEVTLRLSTKSDSQELAYQKLDQLESQ
IKAISTIDGQLLGDLLYGYGEDNSLARETFQLLKKADKTITAAESLTAGLFQSKIADFPGSSSIFNGGFVTYSIEEKAKM
LEIPFADLQRKGVVSDYTAKQMANQARLLTESDIGVSLTGVAGPDFLEGQQAGTVFIGISTKEKVESYKVLIGGRSRSDV
RYIACLHAFNLVRKTLLNTQNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1063742 ACG3JH_RS08185 WP_003103228.1 1583896..1585167(+) (cinA) [Streptococcus parauberis strain DB-M1]
ATGAAAGCTGAATTAATCGCAGTCGGAACAGAAATCTTGACCGGTCAAATAGTTAATACGAACGCACAGTTTTTATCAGA
AAAAATGGCAGAGATTGGAGTTGATGTCTATTATCATACAGCAGTAGGCGATAATGAAATCAGATTATTAAATATCCTTG
AAGTTGCAAGTAAACGTAGTGATTTAGTGATATTATGTGGCGGTTTGGGACCTACTGAGGATGATTTGACTAAACAAACG
CTGGCTAAGTTTTTAGGTCTGTCATTGGTCTTTGACAGAGAAGCTAGTCAAAAACTGGACCAATTTTTTTCCTCTCGGTC
TGAGAGTTCTAGAACTCCAAATAATGAGAGGCAAGCACAGTTGATTGAAGGGTCCAAACCTATTCAAAACATTACAGGTC
TAGCTGTTGGTGGTTTAATCGAAAAAGCTGGTGTAACTTATGTCGTCTTACCTGGACCGCCTAGTGAATTGAAACCAATG
GTTAATCAGTATCTACTACCACTGTTGCTGAATGAGGAAACTAAACTCTACTCTCGTGTTTTACGTTTTTTTGGAATTGG
AGAAAGCCAATTAGTTACTATTTTAGCTGATCTTATTGCAAATCAATCAGACCCAACAATTGCTCCCTATGCCAAAATCG
GCGAGGTAACATTGCGCTTGTCAACTAAGTCTGATTCTCAAGAGCTAGCTTATCAAAAATTGGATCAATTAGAAAGTCAG
ATTAAGGCCATTTCAACTATAGATGGACAATTATTAGGAGACTTATTATATGGATATGGTGAGGATAATAGCCTGGCGCG
TGAGACTTTCCAGTTGTTAAAAAAAGCAGATAAGACAATTACAGCTGCAGAAAGTTTAACAGCAGGGCTATTCCAATCTA
AAATTGCTGATTTTCCAGGGTCATCCAGTATTTTTAACGGTGGATTTGTTACCTATAGTATCGAAGAAAAGGCAAAAATG
TTAGAGATTCCATTTGCTGATTTACAACGAAAAGGTGTTGTTAGTGATTATACTGCTAAACAAATGGCTAATCAAGCACG
ACTCTTAACTGAAAGTGATATTGGTGTTAGCTTAACTGGCGTTGCTGGTCCGGATTTCTTGGAAGGACAACAAGCAGGAA
CAGTTTTTATTGGTATTTCGACAAAAGAAAAAGTAGAATCATATAAGGTACTAATTGGCGGCAGGAGTCGCTCAGATGTC
AGATATATAGCTTGCTTACATGCCTTCAACCTAGTCCGAAAAACTTTATTAAATACCCAAAATTTGTTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UCS4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.292

98.818

0.704
  cinA Streptococcus mitis NCTC 12261

71.053

98.818

0.702
  cinA Streptococcus mutans UA159

70.213

100

0.702
  cinA Streptococcus pneumoniae TIGR4

70.096

98.818

0.693
  cinA Streptococcus pneumoniae Rx1

69.856

98.818

0.69
  cinA Streptococcus pneumoniae R6

69.856

98.818

0.69
  cinA Streptococcus pneumoniae D39

69.617

98.818

0.688
  cinA Streptococcus suis isolate S10

53.606

98.345

0.527
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

98.818

0.461

Multiple sequence alignment