Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   AABA14_RS02565 Genome accession   NZ_AP028607
Coordinates   489472..491148 (-) Length   558 a.a.
NCBI ID   WP_338168497.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 484472..496148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA14_RS02535 (TKY123642_04870) - 484805..485134 (-) 330 WP_000132575.1 hypothetical protein -
  AABA14_RS02540 (TKY123642_04880) - 485409..485747 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  AABA14_RS02545 (TKY123642_04890) comE/blpR 485752..486489 (+) 738 WP_001219124.1 response regulator transcription factor Regulator
  AABA14_RS02550 (TKY123642_04900) - 486503..487843 (+) 1341 WP_061764627.1 sensor histidine kinase -
  AABA14_RS02555 (TKY123642_04910) blpC 487888..488043 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  AABA14_RS02560 (TKY123642_04920) - 488100..489461 (-) 1362 WP_061764626.1 bacteriocin secretion accessory protein -
  AABA14_RS02565 (TKY123642_04930) comA/nlmT 489472..491148 (-) 1677 WP_338168497.1 peptide cleavage/export ABC transporter Regulator
  AABA14_RS02570 (TKY123642_04940) comA/nlmT 491042..491629 (-) 588 WP_050111533.1 cysteine peptidase family C39 domain-containing protein Regulator
  AABA14_RS02575 (TKY123642_04950) blpM 491910..492164 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  AABA14_RS02580 (TKY123642_04960) blpN 492180..492383 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  AABA14_RS02585 (TKY123642_04970) cipB 492627..492776 (+) 150 WP_001818346.1 bacteriocin-like peptide BlpO Regulator
  AABA14_RS02590 - 492880..492999 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  AABA14_RS02595 (TKY123642_04990) - 493785..494168 (+) 384 WP_016398494.1 hypothetical protein -
  AABA14_RS02600 (TKY123642_05000) - 494220..494909 (+) 690 WP_050220778.1 CPBP family intramembrane glutamic endopeptidase -
  AABA14_RS02605 blpZ 495016..495183 (+) 168 WP_309543760.1 immunity protein BlpZ -
  AABA14_RS02610 - 495334..495945 (+) 612 WP_044814721.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62919.15 Da        Isoelectric Point: 6.7844

>NTDB_id=106263 AABA14_RS02565 WP_338168497.1 489472..491148(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep2]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTTKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=106263 AABA14_RS02565 WP_338168497.1 489472..491148(-) (comA/nlmT) [Streptococcus pneumoniae strain Sep2]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GACTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus pneumoniae Rx1

67.384

100

0.674
  comA Streptococcus pneumoniae D39

67.384

100

0.674
  comA Streptococcus pneumoniae R6

67.384

100

0.674
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

67.025

100

0.67
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667

Multiple sequence alignment