Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   AABA14_RS02545 Genome accession   NZ_AP028607
Coordinates   485752..486489 (+) Length   245 a.a.
NCBI ID   WP_001219124.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep2     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 480752..491489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA14_RS02515 (TKY123642_04830) - 482085..482372 (-) 288 WP_000777753.1 hypothetical protein -
  AABA14_RS02520 (TKY123642_04840) - 482382..482792 (-) 411 WP_001278304.1 HIT family protein -
  AABA14_RS02525 (TKY123642_04850) pptA 482860..483591 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  AABA14_RS02530 (TKY123642_04860) - 483588..484637 (+) 1050 WP_000653764.1 ABC transporter permease -
  AABA14_RS02535 (TKY123642_04870) - 484805..485134 (-) 330 WP_000132575.1 hypothetical protein -
  AABA14_RS02540 (TKY123642_04880) - 485409..485747 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  AABA14_RS02545 (TKY123642_04890) comE/blpR 485752..486489 (+) 738 WP_001219124.1 response regulator transcription factor Regulator
  AABA14_RS02550 (TKY123642_04900) - 486503..487843 (+) 1341 WP_061764627.1 sensor histidine kinase -
  AABA14_RS02555 (TKY123642_04910) blpC 487888..488043 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  AABA14_RS02560 (TKY123642_04920) - 488100..489461 (-) 1362 WP_061764626.1 bacteriocin secretion accessory protein -
  AABA14_RS02565 (TKY123642_04930) comA/nlmT 489472..491148 (-) 1677 WP_338168497.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28692.86 Da        Isoelectric Point: 6.2357

>NTDB_id=106262 AABA14_RS02545 WP_001219124.1 485752..486489(+) (comE/blpR) [Streptococcus pneumoniae strain Sep2]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=106262 AABA14_RS02545 WP_001219124.1 485752..486489(+) (comE/blpR) [Streptococcus pneumoniae strain Sep2]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCACATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTGGCTAGAAAGATTCGGGAACAAGAC
CCATATGCCCTAATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCTCTGTCCTTTCGCTACCAAGTGTCAGCTTTGGA
CTACATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.036

100

0.535
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.843

98.776

0.384

Multiple sequence alignment