Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACFKHK_RS00435 Genome accession   NZ_CP170760
Coordinates   77497..78678 (+) Length   393 a.a.
NCBI ID   WP_239604415.1    Uniprot ID   -
Organism   Streptococcus parasuis strain FZ2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 72497..83678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFKHK_RS00420 mutL 73263..75200 (+) 1938 WP_392462193.1 DNA mismatch repair endonuclease MutL -
  ACFKHK_RS00425 ruvA 75446..76036 (+) 591 WP_024403269.1 Holliday junction branch migration protein RuvA -
  ACFKHK_RS00430 - 76891..77460 (+) 570 WP_171989012.1 DNA-3-methyladenine glycosylase I -
  ACFKHK_RS00435 cinA 77497..78678 (+) 1182 WP_239604415.1 competence/damage-inducible protein A Machinery gene
  ACFKHK_RS00440 recA 78730..79884 (+) 1155 WP_392462196.1 recombinase RecA Machinery gene
  ACFKHK_RS00445 spx 80098..80496 (+) 399 WP_024392835.1 transcriptional regulator Spx -
  ACFKHK_RS00450 - 80606..80872 (+) 267 WP_130554425.1 IreB family regulatory phosphoprotein -
  ACFKHK_RS00455 ruvX 80872..81291 (+) 420 WP_130554426.1 Holliday junction resolvase RuvX -
  ACFKHK_RS00460 - 81303..81623 (+) 321 WP_024392832.1 DUF1292 domain-containing protein -
  ACFKHK_RS00465 - 81846..82394 (+) 549 WP_174846502.1 nucleotidyltransferase family protein -
  ACFKHK_RS00470 comX/sigX 82576..83046 (+) 471 WP_024392830.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42738.67 Da        Isoelectric Point: 4.5002

>NTDB_id=1059244 ACFKHK_RS00435 WP_239604415.1 77497..78678(+) (cinA) [Streptococcus parasuis strain FZ2]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDLVILCGGLGPTEDDLTKQT
LATFLQKELVADELAMAKLDRFFASRPGRVRTHNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRVFFYAYGDDNSLVKTVATLLEEKKQSLGILENGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVKPESTVDNVLAKVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=1059244 ACFKHK_RS00435 WP_239604415.1 77497..78678(+) (cinA) [Streptococcus parasuis strain FZ2]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATTGATGTATACTTCCACACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTGCTTG
AAATTGCAAGTAAACGAAGTGATCTGGTCATTTTATGTGGTGGTTTAGGTCCTACTGAAGACGACTTGACTAAGCAAACT
TTAGCGACATTTTTGCAAAAAGAGTTGGTTGCTGACGAACTAGCGATGGCAAAATTAGACCGTTTTTTTGCCAGTCGACC
AGGTCGTGTTCGCACACATAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAACTCAAGGCCATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAACAACTTTACTCGCGTGTCCTACGCTTTTTTGGAATAGG
TGAAAGCCAGTTGGTGACTGTTTTAGCGGATTTGATTGACAAGCAGACAGACCCGACTCTTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTATCTACGAAGGCAGATAGCCAGGAAGAAGCGAACGTTCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGTTTTTTTCTATGCATATGGGGATGACAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAAAGAAACAATCTTTGGGCATCCTAGAGAATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGTGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGCTATCAGAAGAAGCA
AGTCGCATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTTGTGTCGGTGGCGGTCAAACCAGAATCAACAGTAGACAA
CGTACTTGCTAAAGTATATCTAGCCTTGGCCAGTACCTCGGGTATTTCCAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGTCAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

55.048

100

0.583
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Streptococcus mutans UA159

54.988

100

0.575
  cinA Bacillus subtilis subsp. subtilis str. 168

46.906

78.117

0.366

Multiple sequence alignment