Detailed information NTG1056502

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DYB47_RS08735
• Genome accession: NZ_UHFV01000002
• Coordinates: 1734219..1735118 (-)
• Length: 299 a.a.
• NCBI ID: WP_003081230.1
• Uniprot ID: G5JW24
• Organism: Streptococcus macacae NCTC 11558
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1729219..1740118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS08710 (NCTC11558_01770)	-	1729469..1730179 (-)	711	WP_003081962.1	SDR family NAD(P)-dependent oxidoreductase	-
DYB47_RS08715 (NCTC11558_01771)	-	1730169..1730912 (-)	744	WP_003079181.1	methyltransferase domain-containing protein	-
DYB47_RS08720 (NCTC11558_01772)	-	1730905..1732053 (-)	1149	WP_003081650.1	hypothetical protein	-
DYB47_RS08725 (NCTC11558_01773)	-	1732278..1732997 (-)	720	WP_003079935.1	ABC transporter permease	-
DYB47_RS08730 (NCTC11558_01774)	-	1732990..1733835 (-)	846	WP_003081858.1	ABC transporter ATP-binding protein	-
DYB47_RS08735 (NCTC11558_01776)	comR	1734219..1735118 (-)	900	WP_003081230.1	helix-turn-helix domain-containing protein	Regulator
DYB47_RS09950	-	1735400..1735525 (-)	126	WP_412093831.1	hypothetical protein	-
DYB47_RS08750	-	1735826..1736005 (+)	180	WP_327078764.1	transposase	-
DYB47_RS09900	-	1735959..1737144 (-)	1186	Protein_1663	polyketide synthase	-
DYB47_RS09665 (NCTC11558_01780)	-	1737259..1737414 (-)	156	WP_172459288.1	hypothetical protein	-
DYB47_RS08760 (NCTC11558_01781)	-	1737526..1738263 (-)	738	WP_002275935.1	ABC transporter permease	-
DYB47_RS08765 (NCTC11558_01782)	-	1738260..1739126 (-)	867	WP_003079247.1	ATP-binding cassette domain-containing protein	-
DYB47_RS08775	-	1739568..1740087 (-)	520	Protein_1667	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 34343.18 Da
• Isoelectric Point: 4.4353

>NTDB_id=1056502 DYB47_RS08735 WP_003081230.1 1734219..1735118(-) (comR) [Streptococcus macacae NCTC 11558]
MSVKETIGQKIREEREKKGLSREQLCAGEEELTVRQLVRIELGQSLPSIVKLEYIADVLKTDLSTLLAGENITIPEDYFA
MKYQLFKFPSYGDSERLSKKVQMIEDIYEKYFEILPEEELFTLELMDNALDYLTIGKTASAEVIFEDFFKQLLLKDTYSL
NDLLLVKYYAIQCQSTKTYDEATLQTLENKILQQETSGDEYYNIELLGVLTAVAGVYLDHGSYSRLKTLTDRMSEVVTKT
QQHSAKPLVLIYEAKYYLYAEHNKEKAKECYDLAALLAQNFGDEVLEANLLAERKSDGI

Nucleotide

• Length: 900 bp

>NTDB_id=1056502 DYB47_RS08735 WP_003081230.1 1734219..1735118(-) (comR) [Streptococcus macacae NCTC 11558]
ATGAGTGTAAAGGAGACCATTGGTCAGAAGATTAGGGAAGAAAGGGAGAAAAAGGGTTTATCACGAGAGCAGCTGTGTGC
TGGGGAGGAAGAGCTAACGGTTCGGCAGTTGGTCCGGATTGAGTTGGGGCAGTCTTTGCCTTCTATTGTGAAGTTAGAAT
ACATTGCTGATGTTTTGAAGACTGATTTGTCAACTCTGCTTGCAGGGGAGAATATCACAATCCCGGAGGACTATTTCGCT
ATGAAATATCAATTATTTAAATTTCCTAGCTATGGTGATTCAGAACGGCTGTCTAAAAAGGTCCAAATGATTGAAGATAT
TTATGAAAAGTATTTTGAGATTTTGCCAGAAGAAGAATTGTTTACCCTAGAATTAATGGATAACGCTCTAGATTATCTGA
CCATTGGCAAGACCGCTTCAGCAGAAGTTATCTTTGAAGATTTCTTTAAACAGCTCTTACTAAAAGATACTTATTCCCTG
AATGATTTATTATTAGTCAAATATTATGCTATCCAATGTCAGTCTACAAAAACTTATGATGAAGCTACTTTACAAACACT
AGAGAATAAGATTCTACAGCAAGAAACTTCAGGCGATGAGTATTATAACATTGAGCTTTTAGGAGTATTGACAGCTGTAG
CGGGTGTTTACTTAGATCATGGGTCCTATTCTAGGCTAAAAACGTTAACTGATAGAATGAGTGAGGTCGTGACTAAAACG
CAGCAGCACAGCGCTAAGCCGTTAGTGTTAATATATGAAGCTAAATATTATCTTTATGCAGAACATAATAAAGAAAAAGC
AAAGGAGTGTTATGATTTAGCTGCTTTGCTAGCACAAAATTTCGGGGATGAAGTCCTAGAAGCAAATCTTCTTGCTGAAA
GAAAAAGTGATGGAATATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (11-64)

• ComR tetratricopeptide (ComR_TPR) (75-293)

3D structure

• AlphaFold DB: G5JW24

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus salivarius strain HSISS4	42.475	100	0.425
comR	Streptococcus salivarius SK126	42.475	100	0.425
comR	Streptococcus thermophilus LMG 18311	42.14	100	0.421
comR	Streptococcus thermophilus LMD-9	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.415