Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ACE2AN_RS04455 Genome accession   NZ_CP169564
Coordinates   868132..868782 (+) Length   216 a.a.
NCBI ID   WP_000387336.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 863132..873782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS04425 - 863616..863831 (+) 216 WP_001232082.1 YozE family protein -
  ACE2AN_RS04430 - 863917..864885 (+) 969 WP_000658183.1 PhoH family protein -
  ACE2AN_RS04435 - 865078..865578 (+) 501 WP_050217691.1 GNAT family N-acetyltransferase -
  ACE2AN_RS04440 - 865581..865906 (+) 326 Protein_875 TfoX/Sxy family protein -
  ACE2AN_RS04445 ald 866207..867318 (-) 1112 Protein_876 alanine dehydrogenase -
  ACE2AN_RS04450 - 867495..868064 (+) 570 WP_000443774.1 GNAT family N-acetyltransferase -
  ACE2AN_RS04455 comEA/celA/cilE 868132..868782 (+) 651 WP_000387336.1 ComEA family DNA-binding protein Machinery gene
  ACE2AN_RS04460 comEC/celB 868766..871006 (+) 2241 WP_081528465.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACE2AN_RS04465 - 871185..871373 (+) 189 WP_138027090.1 hypothetical protein -
  ACE2AN_RS04470 - 871406..871993 (+) 588 WP_375060610.1 ATP-binding cassette domain-containing protein -
  ACE2AN_RS04475 - 871997..873178 (+) 1182 WP_375060611.1 hypothetical protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23189.54 Da        Isoelectric Point: 5.5171

>NTDB_id=1052177 ACE2AN_RS04455 WP_000387336.1 868132..868782(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 6_2F1]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1052177 ACE2AN_RS04455 WP_000387336.1 868132..868782(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 6_2F1]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

91.204

100

0.912
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment