Detailed information NTG1052178

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACE2AN_RS04460
• Genome accession: NZ_CP169564
• Coordinates: 868766..871006 (+)
• Length: 746 a.a.
• NCBI ID: WP_081528465.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 6_2F1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 863766..876006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACE2AN_RS04430	-	863917..864885 (+)	969	WP_000658183.1	PhoH family protein	-
ACE2AN_RS04435	-	865078..865578 (+)	501	WP_050217691.1	GNAT family N-acetyltransferase	-
ACE2AN_RS04440	-	865581..865906 (+)	326	Protein_875	TfoX/Sxy family protein	-
ACE2AN_RS04445	ald	866207..867318 (-)	1112	Protein_876	alanine dehydrogenase	-
ACE2AN_RS04450	-	867495..868064 (+)	570	WP_000443774.1	GNAT family N-acetyltransferase	-
ACE2AN_RS04455	comEA/celA/cilE	868132..868782 (+)	651	WP_000387336.1	ComEA family DNA-binding protein	Machinery gene
ACE2AN_RS04460	comEC/celB	868766..871006 (+)	2241	WP_081528465.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACE2AN_RS04465	-	871185..871373 (+)	189	WP_138027090.1	hypothetical protein	-
ACE2AN_RS04470	-	871406..871993 (+)	588	WP_375060610.1	ATP-binding cassette domain-containing protein	-
ACE2AN_RS04475	-	871997..873178 (+)	1182	WP_375060611.1	hypothetical protein	-
ACE2AN_RS04480	infC	873485..874015 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
ACE2AN_RS04485	rpmI	874048..874248 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
ACE2AN_RS04490	rplT	874300..874659 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
ACE2AN_RS04495	-	874717..875097 (+)	381	WP_000157138.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84571.10 Da
• Isoelectric Point: 9.6345

>NTDB_id=1052178 ACE2AN_RS04460 WP_081528465.1 868766..871006(+) (comEC/celB) [Streptococcus pneumoniae strain 6_2F1]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLNTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTILCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
ENVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1052178 ACE2AN_RS04460 WP_081528465.1 868766..871006(+) (comEC/celB) [Streptococcus pneumoniae strain 6_2F1]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGAACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGATATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGAATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGACGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGACACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-177)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae D39	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae R6	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae Rx1	97.721	100	0.977
comEC/celB	Streptococcus mitis NCTC 12261	91.678	99.866	0.916
comEC/celB	Streptococcus mitis SK321	91.555	100	0.916
comEC	Lactococcus lactis subsp. cremoris KW2	44.13	99.33	0.438