Detailed information NTG1049839

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: ACEPA4_RS15785
• Genome accession: NZ_CP169216
• Coordinates: 3413738..3414994 (+)
• Length: 418 a.a.
• NCBI ID: WP_070490390.1
• Uniprot ID: A0AAP7M5G3
• Organism: Stenotrophomonas sp. P2112
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	3404887..3431300	3413738..3414994	within	0

Gene organization within MGE regions

Location: 3404887..3431300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEPA4_RS15745 (ACEPA4_15745)	-	3404887..3406101 (+)	1215	WP_219634362.1	glycosyltransferase family 4 protein	-
ACEPA4_RS15750 (ACEPA4_15750)	-	3406145..3407341 (+)	1197	WP_235643011.1	lipopolysaccharide biosynthesis protein	-
ACEPA4_RS15755 (ACEPA4_15755)	-	3407304..3408419 (-)	1116	WP_111202054.1	glycosyltransferase	-
ACEPA4_RS15760 (ACEPA4_15760)	-	3408416..3409228 (-)	813	WP_374082884.1	FkbM family methyltransferase	-
ACEPA4_RS15765 (ACEPA4_15765)	-	3409386..3410489 (+)	1104	WP_111202056.1	glycosyltransferase family 4 protein	-
ACEPA4_RS15770 (ACEPA4_15770)	-	3410523..3410939 (-)	417	WP_070490395.1	pilin	-
ACEPA4_RS15775 (ACEPA4_15775)	-	3410943..3412868 (-)	1926	WP_146257844.1	hypothetical protein	-
ACEPA4_RS15780 (ACEPA4_15780)	pilE	3412948..3413382 (-)	435	WP_070490391.1	pilin	Machinery gene
ACEPA4_RS15785 (ACEPA4_15785)	pilC	3413738..3414994 (+)	1257	WP_070490390.1	type II secretion system F family protein	Machinery gene
ACEPA4_RS15790 (ACEPA4_15790)	-	3415002..3415865 (+)	864	WP_065185263.1	A24 family peptidase	-
ACEPA4_RS15795 (ACEPA4_15795)	coaE	3415877..3416488 (+)	612	WP_374082885.1	dephospho-CoA kinase	-
ACEPA4_RS15800 (ACEPA4_15800)	-	3416568..3416954 (-)	387	WP_279945997.1	hypothetical protein	-
ACEPA4_RS15805 (ACEPA4_15805)	-	3417484..3418854 (-)	1371	WP_061479297.1	HAMP domain-containing sensor histidine kinase	-
ACEPA4_RS15810 (ACEPA4_15810)	-	3418817..3419494 (-)	678	WP_005410804.1	response regulator transcription factor	-
ACEPA4_RS15815 (ACEPA4_15815)	-	3419657..3420118 (-)	462	WP_065178936.1	hypothetical protein	-
ACEPA4_RS15820 (ACEPA4_15820)	-	3420234..3420704 (-)	471	WP_005418647.1	hypothetical protein	-
ACEPA4_RS15825 (ACEPA4_15825)	-	3420799..3421278 (-)	480	WP_005418649.1	hypothetical protein	-
ACEPA4_RS15830 (ACEPA4_15830)	rimK	3421537..3422415 (-)	879	WP_005418651.1	30S ribosomal protein S6--L-glutamate ligase	-
ACEPA4_RS15835 (ACEPA4_15835)	-	3422513..3422755 (-)	243	WP_005418653.1	hypothetical protein	-
ACEPA4_RS15840 (ACEPA4_15840)	-	3422901..3423404 (+)	504	WP_139727565.1	hypothetical protein	-
ACEPA4_RS15845 (ACEPA4_15845)	-	3423707..3423928 (-)	222	WP_010481480.1	DUF2188 domain-containing protein	-
ACEPA4_RS15850 (ACEPA4_15850)	-	3424431..3425675 (-)	1245	WP_065185271.1	HlyD family secretion protein	-
ACEPA4_RS15855 (ACEPA4_15855)	-	3425672..3427792 (-)	2121	WP_239499552.1	peptidase domain-containing ABC transporter	-
ACEPA4_RS15860 (ACEPA4_15860)	-	3428153..3428800 (-)	648	WP_231109041.1	type II CAAX prenyl endopeptidase Rce1 family protein	-

Sequence

Protein

• Length: 418 a.a.
• Molecular weight: 45535.96 Da
• Isoelectric Point: 10.2432

>NTDB_id=1049839 ACEPA4_RS15785 WP_070490390.1 3413738..3414994(+) (pilC) [Stenotrophomonas sp. P2112]
MSVSRSAIKKEPVARSTTDLQPFVWVGTDKRGVKMKGEQAAKNANLLRAELRRQGITPGMVKPKPKPLFGAAGSKVSPKD
IAFFSRQMATMMKSGVPIVSALDIIASGHKNPRMKKMVDGIRTDIEGGSSLHEAISKYPVQFDELYRNLVRAGEGAGVLE
TVLDTVANYKENIEALKGKIKKALFYPAMVIAVALLVSSILLIWVVPQFEDVFRGFGADLPAFTQMIVAASRFMVSWWWL
IAIVVIGSIVGFTMAYKRSPKMQHGMDRLILKVPVIGQIMHNSSIARFARTTAVTFKAGVPLVEALGIVAGATGNTVYEH
AVLRMRDDVSVGYPVNMAMKQTALFPHMVIQMTGIGEEAGALDAMLFKVAEYYELEVNNAVDALSSLLEPMIMVFIGIIV
GGLVIGMYLPIFKLASVV

Nucleotide

• Length: 1257 bp

>NTDB_id=1049839 ACEPA4_RS15785 WP_070490390.1 3413738..3414994(+) (pilC) [Stenotrophomonas sp. P2112]
ATGTCTGTCAGTCGCAGTGCGATCAAGAAGGAGCCCGTGGCGCGCAGCACCACGGACCTGCAGCCGTTTGTCTGGGTGGG
GACCGACAAGCGGGGTGTAAAGATGAAAGGGGAGCAGGCCGCGAAAAACGCGAACCTGCTGCGGGCCGAGCTGCGCCGCC
AAGGCATCACCCCGGGCATGGTTAAGCCAAAGCCCAAGCCACTGTTCGGAGCAGCCGGCAGCAAGGTTTCGCCGAAGGAC
ATTGCTTTCTTCAGCCGTCAGATGGCGACGATGATGAAGTCCGGTGTGCCGATCGTCTCAGCGCTGGACATCATCGCCAG
CGGGCACAAGAACCCACGCATGAAGAAGATGGTGGACGGCATCCGCACCGATATCGAAGGCGGATCGTCCCTTCATGAGG
CGATCAGCAAGTATCCGGTGCAGTTCGACGAGCTCTATCGCAACCTAGTGCGTGCGGGTGAAGGCGCCGGTGTATTGGAG
ACGGTGCTTGATACCGTGGCCAACTACAAAGAGAACATCGAAGCCCTGAAGGGCAAGATCAAAAAGGCTCTGTTTTACCC
TGCAATGGTCATTGCGGTGGCGCTCTTGGTCAGCTCGATCCTGCTGATCTGGGTGGTTCCACAGTTTGAAGACGTTTTCA
GGGGATTTGGTGCCGATCTGCCTGCCTTTACTCAGATGATCGTAGCCGCATCCCGGTTCATGGTCTCTTGGTGGTGGCTG
ATCGCGATCGTCGTCATCGGCAGCATCGTCGGCTTCACCATGGCCTATAAGCGCTCGCCAAAGATGCAACACGGGATGGA
TCGCTTGATCCTGAAGGTGCCAGTCATTGGCCAGATCATGCATAACAGCTCGATCGCACGCTTTGCCCGTACCACCGCTG
TGACCTTCAAGGCCGGCGTGCCGCTGGTAGAAGCCTTGGGTATCGTGGCAGGCGCCACCGGCAATACGGTTTACGAGCAT
GCCGTACTGCGCATGCGCGACGACGTCTCGGTCGGTTACCCGGTCAACATGGCCATGAAGCAGACCGCCCTGTTCCCGCA
CATGGTCATCCAGATGACCGGCATCGGCGAAGAGGCCGGCGCCCTGGACGCCATGCTGTTCAAGGTGGCCGAGTACTATG
AGCTGGAGGTCAACAATGCCGTTGACGCCCTGAGCAGCCTGCTCGAGCCGATGATCATGGTGTTCATTGGTATCATCGTC
GGTGGCCTGGTCATTGGCATGTACCTACCCATCTTCAAATTGGCATCGGTGGTCTGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (84-207)

• Type II secretion system (T2SS), protein F (T2SSF) (288-410)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Legionella pneumophila strain ERS1305867	52.475	96.651	0.507
pilC	Pseudomonas stutzeri DSM 10701	53.283	94.737	0.505
pilC	Acinetobacter baylyi ADP1	51.724	97.129	0.502
pilC	Acinetobacter baumannii D1279779	51.889	94.976	0.493
pilG	Neisseria gonorrhoeae MS11	43.75	95.694	0.419
pilG	Neisseria meningitidis 44/76-A	43.25	95.694	0.414
pilC	Vibrio cholerae strain A1552	40.988	96.89	0.397
pilC	Vibrio campbellii strain DS40M4	40	95.694	0.383