Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACB348_RS09505 Genome accession   NZ_CP167002
Coordinates   1883828..1885099 (-) Length   423 a.a.
NCBI ID   WP_111705299.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 30     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1878828..1890099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB348_RS09480 (ACB348_09480) - 1880798..1881103 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ACB348_RS09485 (ACB348_09485) ruvX 1881115..1881534 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ACB348_RS09490 (ACB348_09490) - 1881531..1881800 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ACB348_RS09495 (ACB348_09495) spx 1881914..1882312 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ACB348_RS09500 (ACB348_09500) recA 1882603..1883739 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ACB348_RS09505 (ACB348_09505) cinA 1883828..1885099 (-) 1272 WP_111705299.1 competence/damage-inducible protein A Machinery gene
  ACB348_RS09510 (ACB348_09510) - 1885168..1885728 (-) 561 WP_023611248.1 DNA-3-methyladenine glycosylase I -
  ACB348_RS09515 (ACB348_09515) ruvA 1885738..1886334 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA -
  ACB348_RS09520 (ACB348_09520) - 1886336..1887556 (-) 1221 WP_032461237.1 MFS transporter -
  ACB348_RS09525 (ACB348_09525) mutL 1887567..1889549 (-) 1983 WP_111705300.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45953.73 Da        Isoelectric Point: 4.7648

>NTDB_id=1036949 ACB348_RS09505 WP_111705299.1 1883828..1885099(-) (cinA) [Streptococcus pyogenes strain Isolate 30]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKLM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
CYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1036949 ACB348_RS09505 WP_111705299.1 1883828..1885099(-) (cinA) [Streptococcus pyogenes strain Isolate 30]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTAATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCTGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACGGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
TGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.267

100

0.693
  cinA Streptococcus mitis SK321

69.544

98.582

0.686
  cinA Streptococcus mitis NCTC 12261

69.065

98.582

0.681
  cinA Streptococcus pneumoniae TIGR4

68.106

98.582

0.671
  cinA Streptococcus pneumoniae Rx1

68.106

98.582

0.671
  cinA Streptococcus pneumoniae R6

68.106

98.582

0.671
  cinA Streptococcus pneumoniae D39

67.866

98.582

0.669
  cinA Streptococcus suis isolate S10

52.885

98.345

0.52
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456

Multiple sequence alignment