Detailed information NTG1034052

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DXE64_RS13090
• Genome accession: NZ_LT992470
• Coordinates: 2565829..2566542 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus isolate 13_LA_301
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2560829..2571542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DXE64_RS13060	sph	2561608..2562432 (-)	825	Protein_2449	sphingomyelin phosphodiesterase	-
DXE64_RS13065	-	2562489..2563526 (-)	1038	WP_000857191.1	tyrosine-type recombinase/integrase	-
DXE64_RS13070	-	2563599..2564048 (-)	450	WP_231915586.1	hypothetical protein	-
DXE64_RS13075	-	2564148..2564330 (-)	183	WP_000705248.1	hypothetical protein	-
DXE64_RS13080	-	2564534..2564875 (-)	342	WP_000591749.1	hypothetical protein	-
DXE64_RS13085	-	2564881..2565813 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
DXE64_RS13090	irvR	2565829..2566542 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
DXE64_RS13095	-	2566505..2566678 (+)	174	WP_001801500.1	hypothetical protein	-
DXE64_RS13100	-	2566675..2566956 (+)	282	WP_000854074.1	helix-turn-helix transcriptional regulator	-
DXE64_RS13105	-	2566953..2567168 (+)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
DXE64_RS13110	-	2567157..2567486 (-)	330	WP_000128907.1	hypothetical protein	-
DXE64_RS13115	-	2567537..2568289 (+)	753	WP_001148605.1	phage antirepressor KilAC domain-containing protein	-
DXE64_RS13120	-	2568305..2568502 (+)	198	WP_001148862.1	hypothetical protein	-
DXE64_RS13125	-	2568489..2568869 (-)	381	WP_000762519.1	DUF2513 domain-containing protein	-
DXE64_RS13130	-	2568924..2569247 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
DXE64_RS13135	-	2569244..2569405 (+)	162	WP_000048129.1	DUF1270 family protein	-
DXE64_RS13140	-	2569500..2569802 (+)	303	WP_000165371.1	DUF2482 family protein	-
DXE64_RS13145	-	2569807..2570067 (+)	261	WP_000291510.1	DUF1108 family protein	-
DXE64_RS13150	-	2570076..2570339 (+)	264	WP_001205732.1	hypothetical protein	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=1034052 DXE64_RS13090 WP_001031454.1 2565829..2566542(-) (irvR) [Staphylococcus aureus isolate 13_LA_301]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=1034052 DXE64_RS13090 WP_001031454.1 2565829..2566542(-) (irvR) [Staphylococcus aureus isolate 13_LA_301]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401