Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AB8Z00_RS04170 Genome accession   NZ_CP165720
Coordinates   870794..872044 (+) Length   416 a.a.
NCBI ID   WP_011667974.1    Uniprot ID   M5AZ98
Organism   Levilactobacillus brevis strain NS2301G3     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 865794..877044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB8Z00_RS04150 (AB8Z00_04150) yfmF 866508..867803 (+) 1296 WP_082265224.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  AB8Z00_RS04155 (AB8Z00_04155) yfmH 867781..869070 (+) 1290 WP_021742877.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  AB8Z00_RS04160 (AB8Z00_04160) - 869184..870089 (+) 906 WP_024855103.1 helix-turn-helix domain-containing protein -
  AB8Z00_RS04165 (AB8Z00_04165) pgsA 870151..870738 (+) 588 WP_011668109.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB8Z00_RS04170 (AB8Z00_04170) cinA 870794..872044 (+) 1251 WP_011667974.1 competence/damage-inducible protein A Machinery gene
  AB8Z00_RS04175 (AB8Z00_04175) recA 872138..873271 (+) 1134 WP_011667973.1 recombinase RecA Machinery gene
  AB8Z00_RS04180 (AB8Z00_04180) - 873354..873506 (-) 153 WP_011667972.1 hypothetical protein -
  AB8Z00_RS04185 (AB8Z00_04185) rny 873834..875393 (+) 1560 WP_011667971.1 ribonuclease Y -
  AB8Z00_RS04190 (AB8Z00_04190) - 875525..876319 (+) 795 WP_011667970.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44778.88 Da        Isoelectric Point: 5.2849

>NTDB_id=1031344 AB8Z00_RS04170 WP_011667974.1 870794..872044(+) (cinA) [Levilactobacillus brevis strain NS2301G3]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDQDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=1031344 AB8Z00_RS04170 WP_011667974.1 870794..872044(+) (cinA) [Levilactobacillus brevis strain NS2301G3]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGCGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGTTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAACCCTTAGCAAATCGGACGGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGAAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGCACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCAAGATGGTGTGGTTAGTGCGGCCACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGCTGGA
TACTGATTTTTCGTTGAGCTTCACAGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGACAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB M5AZ98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.471

100

0.445

Multiple sequence alignment