Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   AB6M97_RS10475 Genome accession   NZ_CP163514
Coordinates   2108493..2109434 (-) Length   313 a.a.
NCBI ID   WP_121835694.1    Uniprot ID   A0A3L9DNW3
Organism   Streptococcus hillyeri strain S23-3001-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2103493..2114434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M97_RS10450 (AB6M97_10450) - 2103911..2104117 (-) 207 WP_121835684.1 helix-turn-helix transcriptional regulator -
  AB6M97_RS10455 (AB6M97_10455) - 2104291..2105046 (+) 756 WP_121835686.1 XRE family transcriptional regulator -
  AB6M97_RS10460 (AB6M97_10460) - 2105059..2105871 (+) 813 WP_121835688.1 hypothetical protein -
  AB6M97_RS10465 (AB6M97_10465) - 2106001..2107446 (+) 1446 WP_121835690.1 recombinase family protein -
  AB6M97_RS10470 (AB6M97_10470) comYB 2107526..2108611 (-) 1086 WP_281272442.1 competence type IV pilus assembly protein ComGB Machinery gene
  AB6M97_RS10475 (AB6M97_10475) comGA/cglA 2108493..2109434 (-) 942 WP_121835694.1 competence type IV pilus ATPase ComGA Machinery gene
  AB6M97_RS10480 (AB6M97_10480) - 2109505..2111871 (-) 2367 Protein_2010 phosphoketolase -
  AB6M97_RS10485 (AB6M97_10485) araA 2111987..2113411 (-) 1425 WP_369350746.1 L-arabinose isomerase -
  AB6M97_RS10490 (AB6M97_10490) - 2113442..2114137 (-) 696 WP_027973185.1 L-ribulose-5-phosphate 4-epimerase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35500.64 Da        Isoelectric Point: 5.8919

>NTDB_id=1030382 AB6M97_RS10475 WP_121835694.1 2108493..2109434(-) (comGA/cglA) [Streptococcus hillyeri strain S23-3001-1]
MVQELAKEIIQKAVDLDVQDIYLLPREINYELFMRIGDERRFMGEYAKEEMASLISHFKFVSGMNVGEKRRSQLGSCDYE
LDNEEKVSLRLSSVRDYRGQESLVIRILFSGRIELKYWFDGLNKLKEKLSGRGLYLFSGPVGSGKTTLMHQLVAERFAGQ
QVISIEDPVEIKDPSMLQLQLNDSIGMTYDALIKLSLRHRPDVLIIGEIRDSETARAVIRASLTGTVVFSTIHAKSIPGV
YARLLELGVSPEELHNSLRGIAYQRLIGKGGIIDYAQDHFQNHQPDQWNAQIDQLVADGHLTFEEGKIEKITS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1030382 AB6M97_RS10475 WP_121835694.1 2108493..2109434(-) (comGA/cglA) [Streptococcus hillyeri strain S23-3001-1]
ATGGTACAAGAACTTGCAAAGGAAATTATTCAGAAAGCAGTGGACTTAGATGTCCAAGACATTTATCTGCTGCCGAGGGA
AATCAACTATGAACTTTTTATGAGAATTGGAGATGAGCGCCGTTTCATGGGTGAGTATGCCAAGGAGGAGATGGCTAGTC
TTATCAGTCACTTTAAGTTTGTATCTGGTATGAATGTTGGTGAAAAACGCCGTAGTCAGCTAGGGTCTTGTGACTACGAA
CTGGATAATGAGGAAAAAGTGAGCTTGCGCTTATCTAGCGTTAGGGATTATCGTGGCCAGGAAAGTCTAGTGATTCGGAT
TCTTTTCAGCGGGCGGATTGAGCTCAAATACTGGTTTGATGGGCTTAATAAGCTTAAGGAAAAATTATCTGGTCGAGGGC
TCTATCTTTTTTCGGGGCCAGTTGGGAGTGGCAAAACAACCTTGATGCATCAATTGGTCGCTGAGCGCTTTGCAGGTCAG
CAAGTCATTTCCATCGAAGATCCTGTAGAGATAAAAGACCCGTCCATGCTTCAGTTACAACTCAATGACAGTATTGGCAT
GACTTATGATGCTTTGATAAAGCTGTCGCTCCGCCATAGACCAGATGTTCTGATTATTGGTGAAATTCGTGACAGTGAGA
CGGCGCGTGCGGTGATTAGAGCCAGTCTAACAGGAACTGTTGTCTTTTCAACCATTCACGCTAAAAGTATCCCAGGAGTC
TATGCTAGATTATTAGAATTAGGGGTATCTCCAGAAGAACTTCACAATAGTTTACGAGGGATTGCTTATCAGCGTCTTAT
CGGGAAAGGAGGAATTATTGATTATGCCCAAGACCATTTCCAAAACCACCAGCCGGACCAGTGGAATGCACAGATTGATC
AGCTTGTTGCAGATGGACATCTCACTTTTGAAGAAGGAAAAATCGAAAAAATTACGTCTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L9DNW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.387

99.042

0.677
  comYA Streptococcus mutans UA159

68.167

99.361

0.677
  comYA Streptococcus mutans UA140

67.846

99.361

0.674
  comYA Streptococcus gordonii str. Challis substr. CH1

67.203

99.361

0.668
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.705

99.681

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.064

99.681

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.064

99.681

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.064

99.681

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.064

99.681

0.649
  comGA Lactococcus lactis subsp. cremoris KW2

53.526

99.681

0.534
  comGA Latilactobacillus sakei subsp. sakei 23K

42.697

85.304

0.364

Multiple sequence alignment