Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AB6M99_RS10655 Genome accession   NZ_CP163513
Coordinates   2145947..2147218 (-) Length   423 a.a.
NCBI ID   WP_121836247.1    Uniprot ID   A0A3L9DRG5
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2140947..2152218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS10630 (AB6M99_10630) - 2142803..2143114 (-) 312 WP_121836243.1 DUF1292 domain-containing protein -
  AB6M99_RS10635 (AB6M99_10635) ruvX 2143187..2143606 (-) 420 WP_121836244.1 Holliday junction resolvase RuvX -
  AB6M99_RS10640 (AB6M99_10640) - 2143603..2143872 (-) 270 WP_027974214.1 IreB family regulatory phosphoprotein -
  AB6M99_RS10645 (AB6M99_10645) spx 2144149..2144547 (-) 399 WP_121836245.1 transcriptional regulator Spx -
  AB6M99_RS10650 (AB6M99_10650) recA 2144761..2145915 (-) 1155 WP_121836246.1 recombinase RecA Machinery gene
  AB6M99_RS10655 (AB6M99_10655) cinA 2145947..2147218 (-) 1272 WP_121836247.1 competence/damage-inducible protein A Machinery gene
  AB6M99_RS10660 (AB6M99_10660) - 2147343..2147591 (-) 249 Protein_2046 hypothetical protein -
  AB6M99_RS10665 (AB6M99_10665) - 2148126..2148980 (+) 855 WP_369350768.1 helix-turn-helix domain-containing protein -
  AB6M99_RS10670 (AB6M99_10670) - 2149162..2149509 (-) 348 WP_369351236.1 hypothetical protein -
  AB6M99_RS10675 (AB6M99_10675) - 2149521..2150168 (-) 648 WP_183121691.1 hypothetical protein -
  AB6M99_RS10680 (AB6M99_10680) - 2150477..2151337 (+) 861 WP_121836252.1 Rgg/GadR/MutR family transcriptional regulator -
  AB6M99_RS10685 (AB6M99_10685) - 2151643..2152197 (-) 555 WP_121836253.1 DNA-3-methyladenine glycosylase I -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45303.75 Da        Isoelectric Point: 4.6195

>NTDB_id=1030328 AB6M99_RS10655 WP_121836247.1 2145947..2147218(-) (cinA) [Streptococcus hillyeri strain S23-3001-2]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIAAKRSDLVILCGGLGPTEDDLTKQT
LAKYLGKKLVFDSQASQKLDDFFSTRPQYARTPNNERQAQLVEGSIPIQNVTGLAVGGLIEADGVRYVVLPGPPSELKPM
VNENLVPLLSQDHKRLYSRVLRFFGIGESQLVTVLSDLIDEQTDPTIAPYAKTGEVTLRLSTKATSEAEAIARLEGFESQ
ILSVKTLEGKALKELCYGYGDDNSLAQTVVNLLKEKGKTLTAAESLTAGLFQSSIADISGASQVFAGGFVTYSLSEKAKM
LGIAKEDLEGHGVVSAFTAEKMAEQARLLVGSDFAISLTGVAGPDELEGQPVGTVFIGLASEKSVTSIKVVIGGRSRADV
RYIATLHAFNLVRQALLSDEILV

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1030328 AB6M99_RS10655 WP_121836247.1 2145947..2147218(-) (cinA) [Streptococcus hillyeri strain S23-3001-2]
ATGAAAGCTGAACTTATTGCGGTTGGGACCGAAATTTTAACAGGGCAGATTGTCAACACGAATGCTCAATTTTTGTCGGA
GAAAATGGCGGAGCTGGGGATTGATGTGTATTTTCAGACAGCCGTTGGAGACAATGAGGAGCGTCTCTTATCTGTGATTG
ACATTGCGGCAAAGCGGAGCGATTTGGTGATTTTGTGTGGGGGTCTTGGTCCGACTGAGGATGACTTAACCAAGCAGACT
TTGGCGAAATACCTTGGAAAAAAATTGGTTTTTGACTCTCAAGCCAGTCAAAAATTAGATGACTTCTTTTCTACGCGTCC
ACAGTATGCTCGAACACCAAACAATGAACGTCAGGCACAATTAGTGGAAGGATCAATCCCCATCCAAAATGTGACTGGTT
TGGCTGTAGGAGGCTTAATTGAGGCTGATGGGGTTCGTTATGTCGTCTTGCCTGGTCCACCGAGTGAGCTAAAGCCGATG
GTTAATGAAAACCTAGTACCACTTCTAAGTCAGGACCATAAACGCCTGTATTCTCGTGTTCTCCGTTTCTTTGGGATTGG
GGAAAGCCAATTGGTGACGGTTTTGTCTGATCTGATTGATGAGCAGACAGATCCAACCATTGCTCCTTATGCTAAGACGG
GCGAGGTGACCTTGCGTCTCTCGACCAAGGCGACTTCAGAGGCGGAGGCAATTGCTCGTTTAGAGGGGTTCGAAAGTCAA
ATCTTGTCTGTTAAAACCTTAGAAGGAAAAGCTCTCAAGGAGCTCTGCTATGGTTACGGCGATGACAATAGTCTAGCCCA
AACTGTGGTCAACCTACTGAAAGAAAAGGGGAAGACCTTGACAGCAGCTGAGAGTTTAACAGCTGGGCTTTTCCAATCAA
GCATTGCTGATATTTCAGGAGCATCTCAAGTATTTGCAGGTGGTTTTGTGACTTATAGTTTGTCAGAAAAGGCTAAAATG
CTTGGTATTGCTAAGGAAGACTTGGAAGGTCATGGTGTGGTTTCGGCTTTTACGGCTGAAAAAATGGCAGAGCAGGCACG
ATTATTAGTTGGTAGTGATTTTGCAATCTCTCTTACAGGTGTCGCTGGGCCAGATGAACTAGAGGGACAACCGGTAGGAA
CAGTTTTCATAGGACTTGCTAGTGAAAAGAGTGTGACAAGTATTAAGGTGGTAATTGGTGGGCGTAGTCGTGCGGATGTC
CGTTATATCGCCACTCTTCATGCTTTCAATCTTGTGCGTCAGGCTTTATTATCTGATGAAATTTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L9DRG5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.224

99.054

0.735
  cinA Streptococcus mitis NCTC 12261

73.986

99.054

0.733
  cinA Streptococcus pneumoniae TIGR4

72.792

99.054

0.721
  cinA Streptococcus pneumoniae Rx1

72.554

99.054

0.719
  cinA Streptococcus pneumoniae R6

72.554

99.054

0.719
  cinA Streptococcus pneumoniae D39

72.315

99.054

0.716
  cinA Streptococcus mutans UA159

71.631

100

0.716
  cinA Streptococcus suis isolate S10

54.808

98.345

0.539
  cinA Bacillus subtilis subsp. subtilis str. 168

47.368

98.818

0.468

Multiple sequence alignment