Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   BJR96_RS04495 Genome accession   NZ_LT545678
Coordinates   837348..838001 (+) Length   217 a.a.
NCBI ID   WP_000461747.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate SA111     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 832348..843001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJR96_RS04475 (SA111_00888) - 833789..834055 (-) 267 WP_000598734.1 GIY-YIG nuclease family protein -
  BJR96_RS04480 (SA111_00889) - 834048..834812 (-) 765 WP_000611115.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  BJR96_RS04485 (SA111_00890) - 834947..835687 (+) 741 WP_000500220.1 lysophospholipid acyltransferase family protein -
  BJR96_RS04490 (SA111_00891) - 835702..837165 (-) 1464 WP_070005694.1 IS1182-like element IS1563 family transposase -
  BJR96_RS04495 (SA111_00892) comEA/celA/cilE 837348..838001 (+) 654 WP_000461747.1 helix-hairpin-helix domain-containing protein Machinery gene
  BJR96_RS04500 (SA111_00893) comEC/celB 837985..840222 (+) 2238 WP_069986173.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BJR96_RS04505 (SA111_00894) - 840348..841157 (+) 810 WP_000153219.1 Cof-type HAD-IIB family hydrolase -
  BJR96_RS04510 (SA111_00895) - 841168..842112 (+) 945 WP_000200832.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23770.07 Da        Isoelectric Point: 8.3966

>NTDB_id=1027488 BJR96_RS04495 WP_000461747.1 837348..838001(+) (comEA/celA/cilE) [Streptococcus agalactiae isolate SA111]
MFEIVLEKIKSHKWETTGIIVGLLLFGILGLNHFGTHYKDDDLNINLEKKVSTITEKKVPMISHVKDKVSNQVTVDVKGA
VNHPGVYSLPSQSRVTDAIKRAGGLSNLADSKSVNLAQKLQDETVVYVAQKGEKITVVEEEKENNIATQGNSKGKINLNK
ADLSSLQTISGVGAKRAQDILDYRDSQGGFKTIDDLKNVSGIGEKTLEKLRQDVTID

Nucleotide


Download         Length: 654 bp        

>NTDB_id=1027488 BJR96_RS04495 WP_000461747.1 837348..838001(+) (comEA/celA/cilE) [Streptococcus agalactiae isolate SA111]
ATGTTTGAAATAGTATTGGAAAAAATTAAATCGCATAAATGGGAGACAACAGGAATTATTGTAGGACTCTTATTATTTGG
AATTTTGGGTTTAAATCATTTTGGCACTCATTATAAAGACGACGATTTAAATATTAATTTAGAGAAAAAAGTATCAACTA
TAACAGAAAAAAAGGTACCAATGATTAGTCACGTCAAAGATAAAGTATCTAATCAAGTAACGGTTGACGTAAAAGGGGCA
GTCAATCATCCAGGTGTTTATAGTTTGCCTTCTCAAAGTCGTGTAACAGATGCGATTAAGCGTGCAGGTGGACTAAGCAA
TCTCGCTGATAGTAAATCCGTTAATCTAGCACAGAAATTACAAGATGAGACGGTTGTCTATGTTGCTCAAAAAGGTGAAA
AAATAACTGTTGTGGAAGAGGAGAAAGAAAATAATATCGCCACTCAGGGAAATAGTAAGGGGAAAATTAATCTTAATAAA
GCAGATTTATCAAGTCTTCAGACCATATCAGGCGTTGGAGCTAAAAGAGCTCAAGATATTTTAGATTATCGTGATAGTCA
AGGTGGTTTTAAAACTATTGATGACCTCAAAAACGTATCAGGTATTGGTGAGAAAACACTAGAAAAATTACGTCAAGATG
TTACAATTGACTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(153-215)

SLBB domain (SLBB)

(75-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

44.595

100

0.456
  comEA/celA/cilE Streptococcus mitis SK321

44.144

100

0.452
  comEA/celA/cilE Streptococcus pneumoniae Rx1

43.694

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae D39

43.694

100

0.447
  comEA/celA/cilE Streptococcus pneumoniae R6

43.694

100

0.447
  comEA/celA/cilE Streptococcus mitis NCTC 12261

43.243

100

0.442
  comEA Lactococcus lactis subsp. cremoris KW2

38.565

100

0.396
  comEA Streptococcus thermophilus LMD-9

53.896

70.968

0.382