Detailed information NTG1027489

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BJR96_RS04500
• Genome accession: NZ_LT545678
• Coordinates: 837985..840222 (+)
• Length: 745 a.a.
• NCBI ID: WP_069986173.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate SA111
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 832985..845222

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJR96_RS04475 (SA111_00888)	-	833789..834055 (-)	267	WP_000598734.1	GIY-YIG nuclease family protein	-
BJR96_RS04480 (SA111_00889)	-	834048..834812 (-)	765	WP_000611115.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
BJR96_RS04485 (SA111_00890)	-	834947..835687 (+)	741	WP_000500220.1	lysophospholipid acyltransferase family protein	-
BJR96_RS04490 (SA111_00891)	-	835702..837165 (-)	1464	WP_070005694.1	IS1182-like element IS1563 family transposase	-
BJR96_RS04495 (SA111_00892)	comEA/celA/cilE	837348..838001 (+)	654	WP_000461747.1	helix-hairpin-helix domain-containing protein	Machinery gene
BJR96_RS04500 (SA111_00893)	comEC/celB	837985..840222 (+)	2238	WP_069986173.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BJR96_RS04505 (SA111_00894)	-	840348..841157 (+)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
BJR96_RS04510 (SA111_00895)	-	841168..842112 (+)	945	WP_000200832.1	LacI family DNA-binding transcriptional regulator	-
BJR96_RS04515 (SA111_00896)	-	842171..843163 (-)	993	WP_000800992.1	alpha/beta hydrolase fold domain-containing protein	-
BJR96_RS04520 (SA111_00897)	-	843339..844067 (+)	729	WP_000468971.1	methyltransferase domain-containing protein	-
BJR96_RS04525 (SA111_00898)	holA	844121..845158 (+)	1038	WP_069986174.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85457.31 Da
• Isoelectric Point: 9.7374

>NTDB_id=1027489 BJR96_RS04500 WP_069986173.1 837985..840222(+) (comEC/celB) [Streptococcus agalactiae isolate SA111]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDREIIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIEVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLSQHRSFFALMSKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKLAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLSVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=1027489 BJR96_RS04500 WP_069986173.1 837985..840222(+) (comEC/celB) [Streptococcus agalactiae isolate SA111]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAATTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTGAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATCATTGCAGATATCAAACTCGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATCTCAACATAGGTCTTTCTT
TGCTCTTATGTCTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGCCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCACTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTTGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAACTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCAG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTGTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAATCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGAGTAGCTGTAAAATCTATAGAAGCTGGTGATAAACTTTCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGTTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGATCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TGCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (215-458)

• Domain of unknown function (DUF4131) (DUF4131) (28-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.4	100	0.487
comEC/celB	Streptococcus mitis SK321	48.396	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae Rx1	46.452	100	0.466
comEC/celB	Streptococcus pneumoniae D39	46.452	100	0.466
comEC/celB	Streptococcus pneumoniae R6	46.452	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.683	99.866	0.436