Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ABZ559_RS06940 Genome accession   NZ_CP160400
Coordinates   1354982..1355656 (+) Length   224 a.a.
NCBI ID   WP_018375408.1    Uniprot ID   -
Organism   Streptococcus sp. ZY19097     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1349982..1360656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZ559_RS06930 (ABZ559_06930) mmuM 1350761..1351711 (+) 951 WP_367005674.1 homocysteine S-methyltransferase -
  ABZ559_RS06935 (ABZ559_06935) - 1352250..1354796 (+) 2547 WP_367005675.1 M1 family metallopeptidase -
  ABZ559_RS06940 (ABZ559_06940) ciaR 1354982..1355656 (+) 675 WP_018375408.1 response regulator transcription factor Regulator
  ABZ559_RS06945 (ABZ559_06945) ciaH 1355646..1356947 (+) 1302 WP_367005676.1 HAMP domain-containing sensor histidine kinase Regulator
  ABZ559_RS06950 (ABZ559_06950) rpsT 1357167..1357418 (-) 252 WP_074486519.1 30S ribosomal protein S20 -
  ABZ559_RS06955 (ABZ559_06955) coaA 1357472..1358392 (-) 921 WP_018375410.1 type I pantothenate kinase -
  ABZ559_RS06960 (ABZ559_06960) - 1358661..1359251 (+) 591 WP_367005677.1 class I SAM-dependent methyltransferase -
  ABZ559_RS06965 (ABZ559_06965) - 1359248..1360525 (+) 1278 WP_367005678.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25342.96 Da        Isoelectric Point: 4.2031

>NTDB_id=1020936 ABZ559_RS06940 WP_018375408.1 1354982..1355656(+) (ciaR) [Streptococcus sp. ZY19097]
MIKILLVEDDLNLSNSVFDFLDDFADVMQVFDGDEGLYEAESGVYDIILLDLMLPEKDGFQVLKELREKGVSTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKINDNFLQYGDLVVDTSTNTTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTGFVSNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1020936 ABZ559_RS06940 WP_018375408.1 1354982..1355656(+) (ciaR) [Streptococcus sp. ZY19097]
ATGATAAAGATTTTATTAGTTGAAGATGATTTAAATTTATCCAATTCTGTCTTTGATTTTTTAGACGACTTCGCAGACGT
CATGCAAGTCTTTGATGGTGATGAGGGACTTTACGAGGCGGAGAGTGGCGTTTACGATATTATTCTTTTAGATTTGATGT
TGCCAGAAAAGGATGGCTTTCAAGTTCTGAAGGAACTGAGAGAAAAAGGTGTGTCAACGCCAGTTCTCATTATGACAGCC
AAAGAAGGTCTAGATGATAAAGGTCATGGATTTGAACTCGGTGCGGATGATTATTTGACCAAACCTTTTTACTTAGAAGA
ATTAAAAATGCGCATCCAAGCCCTTCTTAAACGTTCTGGTAAGATTAATGACAATTTTCTTCAATATGGGGATTTAGTAG
TTGATACGTCTACAAATACAACCACAGTAAATGGAGAAGAAGTTGAATTATTGGGTAAAGAATTTGATTTATTGGTCTAT
TTTTTACAAAATCAAAATGTTATTTTACCTAAGTCACAAATTTTCGATAGAATATGGGGCTTTGACAGTGATACAACAAT
TTCAGTTGTTGAGGTATATGTGTCAAAAATTCGTAAGAAACTTAAAGGAACAGGTTTTGTTTCAAATCTGCAAACCTTGC
GCAGCGTGGGGTATATTTTAAAAAATGCTGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

99.554

0.897
  ciaR Streptococcus pneumoniae Rx1

86.161

100

0.862
  ciaR Streptococcus pneumoniae D39

86.161

100

0.862
  ciaR Streptococcus pneumoniae R6

86.161

100

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.161

100

0.862
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.946

100

0.379
  micA Streptococcus pneumoniae Cp1015

36.052

100

0.375
  covR Streptococcus salivarius strain HSISS4

36

100

0.362
  vicR Streptococcus mutans UA159

34.615

100

0.362

Multiple sequence alignment