Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DQM60_RS08330 Genome accession   NZ_LS483366
Coordinates   1793534..1795639 (-) Length   701 a.a.
NCBI ID   WP_004183275.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC7366     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1788534..1800639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS08300 (NCTC7366_01675) pptB 1788984..1790018 (-) 1035 WP_415244984.1 ABC transporter permease Regulator
  DQM60_RS08305 (NCTC7366_01676) pptA 1790018..1790749 (-) 732 WP_014632700.1 ABC transporter ATP-binding protein Regulator
  DQM60_RS08310 (NCTC7366_01677) - 1790814..1791233 (+) 420 WP_014632699.1 HIT family protein -
  DQM60_RS08315 (NCTC7366_01678) - 1791230..1791529 (+) 300 WP_084871000.1 hypothetical protein -
  DQM60_RS08320 (NCTC7366_01679) - 1791581..1792309 (-) 729 WP_084871001.1 hypothetical protein -
  DQM60_RS08325 (NCTC7366_01680) - 1792327..1792962 (-) 636 WP_084871002.1 DUF4230 domain-containing protein -
  DQM60_RS08330 (NCTC7366_01682) clpE 1793534..1795639 (-) 2106 WP_004183275.1 AAA family ATPase Regulator
  DQM60_RS08335 (NCTC7366_01684) - 1796373..1797464 (-) 1092 WP_111686661.1 nucleotidyltransferase -
  DQM60_RS08340 (NCTC7366_01685) - 1797471..1798211 (-) 741 WP_049553875.1 class I SAM-dependent DNA methyltransferase -
  DQM60_RS08345 (NCTC7366_01686) rsfS 1798416..1798769 (-) 354 WP_049553874.1 ribosome silencing factor -
  DQM60_RS08350 (NCTC7366_01687) yqeK 1798793..1799383 (-) 591 WP_049553873.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM60_RS08355 (NCTC7366_01688) - 1799380..1800012 (-) 633 WP_045771998.1 nicotinate-nucleotide adenylyltransferase -
  DQM60_RS08360 (NCTC7366_01689) yhbY 1800118..1800435 (-) 318 WP_002884193.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77324.26 Da        Isoelectric Point: 4.7435

>NTDB_id=1020902 DQM60_RS08330 WP_004183275.1 1793534..1795639(-) (clpE) [Streptococcus salivarius strain NCTC7366]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=1020902 DQM60_RS08330 WP_004183275.1 1793534..1795639(-) (clpE) [Streptococcus salivarius strain NCTC7366]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAATATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCGATTTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAATAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAGATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCTGCTCTAGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTAACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCACACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATCCGTTTGGATATGTCA
GAATACAGCGACCGCACAGCTGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGACGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCTTACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTTATCA
CACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACTCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.79

100

0.468
  clpC Lactococcus lactis subsp. cremoris KW2

49.002

92.867

0.455
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpC Bacillus subtilis subsp. subtilis str. 168

45.666

92.154

0.421
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.089

92.867

0.391
  clpC Streptococcus pneumoniae TIGR4

43.087

88.73

0.382
  clpC Streptococcus pneumoniae Rx1

43.087

88.73

0.382
  clpC Streptococcus pneumoniae D39

43.087

88.73

0.382
  clpC Streptococcus thermophilus LMD-9

43.436

88.017

0.382
  clpC Streptococcus thermophilus LMG 18311

42.973

88.302

0.379
  clpC Streptococcus mutans UA159

42.332

89.301

0.378

Multiple sequence alignment