Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ABZ559_RS00375 Genome accession   NZ_CP160400
Coordinates   74632..75891 (+) Length   419 a.a.
NCBI ID   WP_317334318.1    Uniprot ID   -
Organism   Streptococcus sp. ZY19097     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 69632..80891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABZ559_RS00360 (ABZ559_00360) - 71122..71427 (+) 306 WP_273403251.1 lactococcin 972 family bacteriocin -
  ABZ559_RS00365 (ABZ559_00365) - 71485..73491 (+) 2007 WP_018376064.1 DUF1430 domain-containing protein -
  ABZ559_RS00370 (ABZ559_00370) - 73493..74134 (+) 642 WP_018376063.1 ABC transporter ATP-binding protein -
  ABZ559_RS00375 (ABZ559_00375) cinA 74632..75891 (+) 1260 WP_317334318.1 competence/damage-inducible protein A Machinery gene
  ABZ559_RS00380 (ABZ559_00380) recA 75942..77096 (+) 1155 WP_018376061.1 recombinase RecA Machinery gene
  ABZ559_RS00385 (ABZ559_00385) spx 77372..77770 (+) 399 WP_026217171.1 transcriptional regulator Spx -
  ABZ559_RS00390 (ABZ559_00390) - 77842..78285 (-) 444 WP_018376957.1 DUF3021 domain-containing protein -
  ABZ559_RS00395 (ABZ559_00395) - 78303..78746 (-) 444 WP_273403238.1 LytTR family DNA-binding domain-containing protein -
  ABZ559_RS00400 (ABZ559_00400) - 79168..80334 (-) 1167 WP_367005779.1 IS30 family transposase -
  ABZ559_RS00405 (ABZ559_00405) - 80538..80807 (+) 270 WP_026217175.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45540.85 Da        Isoelectric Point: 4.5365

>NTDB_id=1020902 ABZ559_RS00375 WP_317334318.1 74632..75891(+) (cinA) [Streptococcus sp. ZY19097]
MKAELIAVGTEILTGQIVNTNAQFLSEKFAELGIDVFFQTAVGDNEERLLSVIDLASKRSNLVVLCGGLGPTEDDLTKQT
LAKYLGRELVFDEEAIQKLDDFFATRPQYARTPNNERQAQIIEGFIPLQNITGLAVGGLQEVNGVTYVVLPGPPSELKPM
VNEYLVPLLSINHTKLYSRVLRFFGIGESQLVTVLKELIDNQTDPTLAPYAKTGEVTLRLSTKAKTQEEADAKLDVLETQ
ILSVKTLEGVELSQLHYGYGDDNSLAQVAFGLLKEKGKTITAAESLTAGLFQASLADFSGASEVFNGGFVTYSIEEKSKM
LQIPLEDLQSHGVVSAFTAEKMAEQSRFLTNADFGIGLTGVAGPDELEGHPAGTVFLAIASREEVRSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLNA

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1020902 ABZ559_RS00375 WP_317334318.1 74632..75891(+) (cinA) [Streptococcus sp. ZY19097]
ATGAAAGCTGAACTGATTGCTGTAGGCACTGAGATTTTAACAGGACAAATTGTCAATACTAATGCCCAATTTTTATCGGA
GAAATTTGCAGAGTTGGGAATAGATGTCTTTTTCCAGACCGCTGTCGGAGATAATGAAGAACGGCTCTTGTCTGTTATTG
ACCTTGCCAGCAAACGTAGTAATCTGGTAGTACTTTGTGGTGGTCTTGGCCCAACCGAAGACGATCTGACCAAGCAGACT
TTAGCCAAATATCTAGGGCGTGAGTTAGTTTTTGATGAAGAAGCCATTCAGAAGTTGGATGACTTTTTTGCGACGCGTCC
TCAGTATGCACGTACACCCAATAATGAACGGCAAGCACAGATTATTGAAGGGTTTATCCCTCTCCAAAATATCACTGGTT
TGGCAGTTGGAGGCCTACAGGAGGTCAATGGCGTAACTTATGTCGTCTTACCTGGTCCACCAAGTGAACTCAAGCCCATG
GTCAATGAGTATCTTGTTCCTCTGTTGTCAATTAATCACACCAAGTTGTATTCGCGTGTGTTACGCTTCTTTGGGATAGG
TGAGAGTCAGCTAGTGACTGTTTTGAAGGAATTGATTGATAATCAGACAGATCCCACTCTGGCACCTTATGCTAAGACAG
GAGAGGTTACGCTGCGCTTATCGACTAAGGCAAAAACACAAGAAGAAGCTGATGCCAAACTGGATGTTTTGGAAACTCAG
ATTTTATCAGTTAAAACTTTGGAAGGGGTGGAGCTGAGTCAGCTACATTATGGCTATGGTGATGATAATAGTCTTGCACA
GGTAGCTTTTGGATTACTTAAAGAGAAGGGGAAAACTATCACTGCTGCTGAAAGCTTGACGGCAGGTCTCTTTCAAGCCA
GTCTTGCTGATTTTTCAGGAGCCTCTGAGGTATTCAATGGTGGTTTCGTAACTTACAGTATTGAGGAAAAATCTAAAATG
TTGCAGATTCCTTTGGAAGACTTGCAGTCACATGGAGTAGTTAGTGCTTTTACAGCTGAAAAAATGGCAGAGCAGTCTCG
CTTTTTAACAAATGCCGACTTTGGCATCGGTTTGACTGGTGTTGCTGGTCCAGACGAACTTGAAGGACATCCAGCAGGAA
CAGTTTTCCTTGCCATCGCTAGTAGGGAAGAAGTTCGTTCTATAAGGGTTGTTATTGGAGGACGTAGCCGCTCGGACGTT
CGTTACATCGCAACTTTATATGCTTTCAATTTAGTACGCCAAGCTTTATTAAATGCTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

73.923

99.761

0.737
  cinA Streptococcus mitis SK321

73.445

99.761

0.733
  cinA Streptococcus mitis NCTC 12261

72.727

99.761

0.726
  cinA Streptococcus pneumoniae TIGR4

71.531

99.761

0.714
  cinA Streptococcus pneumoniae Rx1

71.531

99.761

0.714
  cinA Streptococcus pneumoniae R6

71.531

99.761

0.714
  cinA Streptococcus pneumoniae D39

71.292

99.761

0.711
  cinA Streptococcus suis isolate S10

56.01

99.284

0.556
  cinA Bacillus subtilis subsp. subtilis str. 168

46.905

100

0.47

Multiple sequence alignment