Detailed information NTG1013068

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ABQ274_RS10275
• Genome accession: NZ_CP159281
• Coordinates: 2069129..2070067 (+)
• Length: 312 a.a.
• NCBI ID: WP_031561106.1
• Uniprot ID: A0AAP8DEI2
• Organism: Lactococcus lactis strain FNZ339
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2064129..2075067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABQ274_RS10275 (ABQ274_10275)	comGA	2069129..2070067 (+)	939	WP_031561106.1	competence type IV pilus ATPase ComGA	Machinery gene
ABQ274_RS10280 (ABQ274_10280)	comGB	2069961..2071034 (+)	1074	Protein_1983	competence type IV pilus assembly protein ComGB	-
ABQ274_RS10285 (ABQ274_10285)	-	2071048..2071188 (+)	141	WP_023164653.1	hypothetical protein	-
ABQ274_RS10290 (ABQ274_10290)	-	2071185..2072642 (-)	1458	WP_353726874.1	recombinase family protein	-
ABQ274_RS10295 (ABQ274_10295)	-	2072762..2073301 (-)	540	WP_023164651.1	PH domain-containing protein	-
ABQ274_RS10300 (ABQ274_10300)	-	2073356..2073940 (-)	585	WP_259771878.1	hypothetical protein	-
ABQ274_RS10305 (ABQ274_10305)	-	2073951..2074358 (-)	408	WP_023189013.1	helix-turn-helix transcriptional regulator	-
ABQ274_RS10310 (ABQ274_10310)	-	2074535..2074768 (+)	234	WP_353726875.1	hypothetical protein	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35707.88 Da
• Isoelectric Point: 5.9473

>NTDB_id=1013068 ABQ274_RS10275 WP_031561106.1 2069129..2070067(+) (comGA) [Lactococcus lactis strain FNZ339]
MIPKMAKELIQRAIDRDASDIYLIASKEKYKLYFRQMTARDLVEEIGLEVGLALLTHFKFLAGMNTGERRRVQLGACWYE
IEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKELDFWFDEELENYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTDLQV
ITIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHASSVRGVIQ
RLSELGLSHWEIKNALSSVVYQRLIAGKGVLDIAKNEFESWSSENWNKKIDQLLTNGYLTPTEAKREKIKTD

Nucleotide

• Length: 939 bp

>NTDB_id=1013068 ABQ274_RS10275 WP_031561106.1 2069129..2070067(+) (comGA) [Lactococcus lactis strain FNZ339]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAGAGCAATTGATAGAGATGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCACGTGATCTGGTAGAAGAAATTGGGTTAGAAGTTGGCTTAGCAC
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACAGGAGAACGCAGACGAGTTCAATTGGGAGCTTGTTGGTATGAA
ATAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCGACAGTGGGGGATTTCGAGGGTAATGAATCTTTAGTAATACGTCT
CTTGCATGATCAAAACAAAGAACTTGATTTTTGGTTTGATGAAGAGCTAGAGAATTATGATTGTAAAAGAGGATTGCATC
TCTTTGCCGGTCCAGTAGGCTCGGGAAAAACATCTTTAATGTTTGATTTAGCTCGTCGTCATTTTACAGATTTACAAGTT
ATCACTATTGAAGAACCCGTTGAGTTGATTGATTCCGATTTTATTCAGTTACAAGTCAACGAAGTCATTGGTAATAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGCCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGTTATACAGTGTTTTCAACCGTTCATGCCTCTTCTGTTAGAGGTGTCATTCAG
AGATTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGCGTTTAATAGCTGG
GAAAGGAGTATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Lactococcus lactis subsp. cremoris KW2	76.923	100	0.769
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	54.984	99.679	0.548
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	53.376	99.679	0.532
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	52.412	99.679	0.522
comGA/cglA/cilD	Streptococcus pneumoniae D39	52.412	99.679	0.522
comGA/cglA/cilD	Streptococcus pneumoniae R6	52.412	99.679	0.522
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	52.412	99.679	0.522
comYA	Streptococcus mutans UA159	52.244	100	0.522
comYA	Streptococcus mutans UA140	52.244	100	0.522
comYA	Streptococcus gordonii str. Challis substr. CH1	51.923	100	0.519