Detailed information NTG1010151

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H1X08_RS01520
• Genome accession: NZ_LR822025
• Coordinates: 287266..289419 (+)
• Length: 717 a.a.
• NCBI ID: WP_180482397.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_961
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 282266..294419

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1X08_RS10545 (STHERMO_0307)	-	282363..282569 (+)	207	WP_011681579.1	hypothetical protein	-
H1X08_RS01510 (STHERMO_0309)	-	282757..284514 (+)	1758	WP_100285003.1	ABC transporter ATP-binding protein	-
H1X08_RS01515 (STHERMO_0310)	-	284507..286252 (+)	1746	WP_180482396.1	ABC transporter ATP-binding protein	-
H1X08_RS01520 (STHERMO_0315)	comA/nlmT	287266..289419 (+)	2154	WP_180482397.1	peptide cleavage/export ABC transporter	Regulator
H1X08_RS01525 (STHERMO_0316)	comB	289435..290802 (+)	1368	WP_180482398.1	bacteriocin secretion accessory protein	Regulator
H1X08_RS01530 (STHERMO_0317)	-	290817..290978 (+)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
H1X08_RS10550	comD/blpH	290996..291799 (-)	804	WP_232086948.1	ATP-binding protein	Regulator
H1X08_RS01540 (STHERMO_0319)	-	292330..293067 (-)	738	WP_180482400.1	LytR/AlgR family response regulator transcription factor	-
H1X08_RS01545 (STHERMO_0320)	-	293318..293494 (+)	177	WP_180482401.1	Blp family class II bacteriocin	-
H1X08_RS01550 (STHERMO_0321)	-	293513..293713 (+)	201	WP_011681569.1	hypothetical protein	-
H1X08_RS01555 (STHERMO_0322)	-	294069..294299 (+)	231	WP_011226494.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80704.58 Da
• Isoelectric Point: 7.0163

>NTDB_id=1010151 H1X08_RS01520 WP_180482397.1 287266..289419(+) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_961]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKNTKDYLIIGDPDPSVKVTKMTKERFEKEWTGITLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFVDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALVRALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIYQGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=1010151 H1X08_RS01520 WP_180482397.1 287266..289419(+) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAACACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTA
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTGACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTGTTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGTGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTTATCAGGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTGATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.787	99.582	0.675
comA	Streptococcus mitis NCTC 12261	66.104	99.163	0.656
comA	Streptococcus pneumoniae Rx1	65.682	99.163	0.651
comA	Streptococcus pneumoniae D39	65.682	99.163	0.651
comA	Streptococcus pneumoniae R6	65.682	99.163	0.651
comA	Streptococcus mitis SK321	65.541	99.163	0.65
comA	Streptococcus pneumoniae TIGR4	65.26	99.163	0.647
comA	Streptococcus gordonii str. Challis substr. CH1	64.286	99.582	0.64