Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   H1X08_RS01525 Genome accession   NZ_LR822025
Coordinates   289435..290802 (+) Length   455 a.a.
NCBI ID   WP_180482398.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_961     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 284435..295802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X08_RS01515 (STHERMO_0310) - 284507..286252 (+) 1746 WP_180482396.1 ABC transporter ATP-binding protein -
  H1X08_RS01520 (STHERMO_0315) comA/nlmT 287266..289419 (+) 2154 WP_180482397.1 peptide cleavage/export ABC transporter Regulator
  H1X08_RS01525 (STHERMO_0316) comB 289435..290802 (+) 1368 WP_180482398.1 bacteriocin secretion accessory protein Regulator
  H1X08_RS01530 (STHERMO_0317) - 290817..290978 (+) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1X08_RS10550 comD/blpH 290996..291799 (-) 804 WP_232086948.1 ATP-binding protein Regulator
  H1X08_RS01540 (STHERMO_0319) - 292330..293067 (-) 738 WP_180482400.1 LytR/AlgR family response regulator transcription factor -
  H1X08_RS01545 (STHERMO_0320) - 293318..293494 (+) 177 WP_180482401.1 Blp family class II bacteriocin -
  H1X08_RS01550 (STHERMO_0321) - 293513..293713 (+) 201 WP_011681569.1 hypothetical protein -
  H1X08_RS01555 (STHERMO_0322) - 294069..294299 (+) 231 WP_011226494.1 bacteriocin class II family protein -
  H1X08_RS01560 (STHERMO_0323) - 294306..294467 (+) 162 WP_011681568.1 hypothetical protein -
  H1X08_RS11190 - 295323..295724 (+) 402 WP_011226490.1 hypothetical protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50410.13 Da        Isoelectric Point: 4.8153

>NTDB_id=1010152 H1X08_RS01525 WP_180482398.1 289435..290802(+) (comB) [Streptococcus thermophilus isolate STH_CIRM_961]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSRAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1010152 H1X08_RS01525 WP_180482398.1 289435..290802(+) (comB) [Streptococcus thermophilus isolate STH_CIRM_961]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCGGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTAACGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAGGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.246

99.121

0.389
  comB Streptococcus pneumoniae D39

39.246

99.121

0.389
  comB Streptococcus pneumoniae R6

39.246

99.121

0.389
  comB Streptococcus pneumoniae TIGR4

38.581

99.121

0.382
  comB Streptococcus mitis SK321

37.916

99.121

0.376
  comB Streptococcus mitis NCTC 12261

37.916

99.121

0.376

Multiple sequence alignment