Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ABKA15_RS04680 Genome accession   NZ_CP157941
Coordinates   946839..947543 (-) Length   234 a.a.
NCBI ID   WP_049512789.1    Uniprot ID   A0A7L8W7D7
Organism   Streptococcus sp. KHUD_010     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 941839..952543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA15_RS04660 (ABKA15_04655) - 942543..943480 (+) 938 Protein_907 IS30 family transposase -
  ABKA15_RS04665 (ABKA15_04660) - 943558..943716 (+) 159 WP_185952229.1 hypothetical protein -
  ABKA15_RS04670 (ABKA15_04665) - 943860..944546 (-) 687 WP_225620253.1 DUF805 domain-containing protein -
  ABKA15_RS04675 (ABKA15_04670) comEC/celB 944627..946855 (-) 2229 WP_049512791.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ABKA15_RS04680 (ABKA15_04675) comEA/celA/cilE 946839..947543 (-) 705 WP_049512789.1 helix-hairpin-helix domain-containing protein Machinery gene
  ABKA15_RS04685 (ABKA15_04680) smpB 947725..948192 (-) 468 WP_049512786.1 SsrA-binding protein SmpB -
  ABKA15_RS04690 (ABKA15_04685) rnr 948155..950488 (-) 2334 WP_049512784.1 ribonuclease R -
  ABKA15_RS04695 (ABKA15_04690) secG 950580..950813 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  ABKA15_RS04700 (ABKA15_04695) rpmG 950853..951002 (-) 150 WP_003024746.1 50S ribosomal protein L33 -
  ABKA15_RS04705 (ABKA15_04700) - 950986..952191 (-) 1206 WP_080984151.1 multidrug efflux MFS transporter -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 24950.94 Da        Isoelectric Point: 4.8720

>NTDB_id=1009119 ABKA15_RS04680 WP_049512789.1 946839..947543(-) (comEA/celA/cilE) [Streptococcus sp. KHUD_010]
MLETIIEKMKEYKILIGLSLIGLIIAGFFMINGQSSRQSNVAELAQETVASSKTESEEISTGTKKNSQKEKAETQTSSSE
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVVYVATVGENATSVASGTGQSSTL
GTSEVASQKGNKVNLNTADLSELQTISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1009119 ABKA15_RS04680 WP_049512789.1 946839..947543(-) (comEA/celA/cilE) [Streptococcus sp. KHUD_010]
ATGTTAGAGACAATCATTGAAAAGATGAAAGAGTATAAAATTTTGATTGGTTTAAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTTATGATAAATGGTCAATCTAGTAGACAATCAAATGTAGCAGAGCTCGCACAGGAAACAGTTGCTAGTTCTAAAA
CAGAATCAGAAGAAATTTCAACTGGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGACTCAAACGAGTTCAAGTGAA
GAATCAGAATTTTTAACCGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCAATTCAAAAAGCGGGTGGTTTAACGACAGATGCTGACAGCAAGTCTATCAATTTGGCGCAAAAACTAACAG
ATGAAGCTGTTGTTTATGTGGCAACTGTTGGTGAGAATGCGACAAGTGTTGCAAGTGGAACAGGACAATCTTCAACGTTA
GGAACTAGTGAAGTCGCATCGCAAAAAGGGAATAAGGTCAATCTAAATACAGCTGATTTATCTGAGCTGCAGACCATTTC
TGGTATTGGTCAAAAACGTGCACAAGATATTTTAGATTATCGTGAGGCAAACGGGAAATTTAATTCCGTTGATGACCTGA
AAAATGTATCAGGAGTAGGTGCTAAAACACTAGAGAAATTGAAGGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W7D7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae Rx1

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae D39

52.34

100

0.526
  comEA/celA/cilE Streptococcus pneumoniae R6

52.34

100

0.526
  comEA/celA/cilE Streptococcus mitis SK321

51.073

99.573

0.509
  comEA Streptococcus thermophilus LMD-9

43.59

100

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

42.489

99.573

0.423

Multiple sequence alignment