Detailed information NTG1009118

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ABKA15_RS04675
• Genome accession: NZ_CP157941
• Coordinates: 944627..946855 (-)
• Length: 742 a.a.
• NCBI ID: WP_049512791.1
• Uniprot ID: -
• Organism: Streptococcus sp. KHUD_010
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 939627..951855

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKA15_RS04645 (ABKA15_04640)	-	940094..940564 (-)	471	WP_003043000.1	8-oxo-dGTP diphosphatase	-
ABKA15_RS04650 (ABKA15_04645)	-	940601..941254 (-)	654	WP_049513377.1	uracil-DNA glycosylase	-
ABKA15_RS04655 (ABKA15_04650)	-	941276..942262 (-)	987	WP_049513380.1	Gfo/Idh/MocA family oxidoreductase	-
ABKA15_RS04660 (ABKA15_04655)	-	942543..943480 (+)	938	Protein_907	IS30 family transposase	-
ABKA15_RS04665 (ABKA15_04660)	-	943558..943716 (+)	159	WP_185952229.1	hypothetical protein	-
ABKA15_RS04670 (ABKA15_04665)	-	943860..944546 (-)	687	WP_225620253.1	DUF805 domain-containing protein	-
ABKA15_RS04675 (ABKA15_04670)	comEC/celB	944627..946855 (-)	2229	WP_049512791.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ABKA15_RS04680 (ABKA15_04675)	comEA/celA/cilE	946839..947543 (-)	705	WP_049512789.1	helix-hairpin-helix domain-containing protein	Machinery gene
ABKA15_RS04685 (ABKA15_04680)	smpB	947725..948192 (-)	468	WP_049512786.1	SsrA-binding protein SmpB	-
ABKA15_RS04690 (ABKA15_04685)	rnr	948155..950488 (-)	2334	WP_049512784.1	ribonuclease R	-
ABKA15_RS04695 (ABKA15_04690)	secG	950580..950813 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
ABKA15_RS04700 (ABKA15_04695)	rpmG	950853..951002 (-)	150	WP_003024746.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85261.19 Da
• Isoelectric Point: 10.0513

>NTDB_id=1009118 ABKA15_RS04675 WP_049512791.1 944627..946855(-) (comEC/celB) [Streptococcus sp. KHUD_010]
MSQWIKRFPIKPIYIAFLLVWLYFAIYQSSWLACLGFIFLVIRLFRFYSPKECFMTFMILSCFAGFFFVRREMVEQKTKV
EPSPVRQVAVLPDTIKVNGDSLSFRGKTNGQTYQVYYKLKSKEEQLAFQNLSSLVILTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHPFEWLSSWRRKVLVFIKKHFPNPMSNYMTGLLFGALDTDFDEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTFWRKIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLT
LIFISSPLIKLTQVNFLFEGLENSIRWIASVFSRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLFLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGVDTIDTLVLTNPNP
DYAGDVLEVAKKFAIKKIYISRSSLSNADFLEKLRKINTFIHVVKQGDKLPIFDHHLKVLSSASKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMIK

Nucleotide

• Length: 2229 bp

>NTDB_id=1009118 ABKA15_RS04675 WP_049512791.1 944627..946855(-) (comEC/celB) [Streptococcus sp. KHUD_010]
ATGTCACAGTGGATTAAAAGATTTCCGATTAAGCCAATTTACATAGCTTTTTTGCTTGTCTGGTTGTATTTTGCAATCTA
CCAAAGTAGTTGGTTAGCTTGTCTTGGTTTTATCTTTCTGGTGATTCGTCTTTTTCGCTTTTATTCACCGAAAGAATGTT
TCATGACCTTCATGATCCTCTCTTGTTTTGCTGGTTTTTTCTTTGTTCGTAGGGAAATGGTAGAGCAGAAGACGAAAGTA
GAACCTTCTCCCGTAAGACAAGTAGCAGTTCTACCCGACACGATTAAGGTAAATGGAGATTCACTTTCTTTCCGTGGTAA
AACAAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGTTATATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGATAGAATCAGCTTGCACCCTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAAAGTACTGGTATTTATCAAGAAGCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACAGACTTCGATGAAATGAACAATCTTTACTCTAGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGCTGGGTCTTACACAGGA
AATGGTCCATAAATGCCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTATTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTGATAGATTTTGAAAG
TCTGACTTTTTGGCGAAAGATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTACTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTGATTTTCGATACAATGATGCTGCCAGGCTTGACG
TTGATTTTTATTTCTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GATAGCAAGTGTCTTTAGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTTTGTTTCTTTCATTGCTCTTTTTCATAAAT
AAATTTCCTTTGCAAAATGAGATCACAATGGTGGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGTGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCGACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTTCCAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATCATCATTTGAAAGTTCTTTCGAGTGCTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAAAATTCATCACATTCAAAGTTTTTACAGCAAATAGAGCCCGCAGTTGCGCTCATTT
CTGTTGGGAAAAATAATCAATCTAAGCAACCAAGTCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAGGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGATCAAGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-583)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.288	100	0.557
comEC/celB	Streptococcus mitis NCTC 12261	55.094	100	0.554
comEC/celB	Streptococcus pneumoniae TIGR4	54.351	100	0.547
comEC/celB	Streptococcus pneumoniae Rx1	53.548	100	0.539
comEC/celB	Streptococcus pneumoniae D39	53.548	100	0.539
comEC/celB	Streptococcus pneumoniae R6	53.548	100	0.539
comEC	Lactococcus lactis subsp. cremoris KW2	46.98	100	0.472