Detailed information NTG1009079

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: ABKA15_RS00040
• Genome accession: NZ_CP157941
• Coordinates: 4827..5576 (+)
• Length: 249 a.a.
• NCBI ID: WP_049512713.1
• Uniprot ID: -
• Organism: Streptococcus sp. KHUD_010
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	5683..6628	4827..5576	flank	107

Gene organization within MGE regions

Location: 4827..6628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABKA15_RS00040 (ABKA15_00040)	comE	4827..5576 (+)	750	WP_049512713.1	competence system response regulator transcription factor ComE	Regulator
ABKA15_RS00045 (ABKA15_00045)	-	5683..6628 (+)	946	Protein_7	IS30 family transposase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29171.84 Da
• Isoelectric Point: 8.9778

>NTDB_id=1009079 ABKA15_RS00040 WP_049512713.1 4827..5576(+) (comE) [Streptococcus sp. KHUD_010]
MKVLVLEDEISHQVRMETALAEIAKEMGITIKVKVTGKVREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLSNVAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETRRFFSPHKSYLVNIGNIKGYDKKMREIIFYEDHRCPITRMKIGKL
KAILEELKG

Nucleotide

• Length: 750 bp

>NTDB_id=1009079 ABKA15_RS00040 WP_049512713.1 4827..5576(+) (comE) [Streptococcus sp. KHUD_010]
ATGAAAGTATTAGTATTAGAAGATGAAATTTCACATCAAGTCAGAATGGAAACAGCTTTGGCAGAGATTGCGAAAGAAAT
GGGAATTACGATAAAAGTTAAAGTAACTGGCAAAGTAAGAGAATTTAAAGAATATATTGAAAATGATGAGGTGAATCAAT
TATATTTTTTAGATATTGATATCAAAGGAGAGGAAACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCACAATCCG
TATGCTATTATTGTTTTTGTTACAACGAAATCAGAATTTGCTACGATGACATTTAAATATAAAGTATCTGCACTGGATTT
TGTTGATAAAAATTTGAGTAATGTTGCTTTTAAAAAACATATAAAAGACAGCATTGAGTATACAAAAGCGACATTGATTG
AAAATAAAGATATGGTGGATTATTTTGAATATAGCTTTCGTGGCGGAGAGGTTAGAATGCCTTTTAATGACATTTTATAT
ATTGAAACGACAGGCTCTTCTCATAAATTAAGAATTGTCGGTAAAAACTTTTTTAAAGAATTTTATGGTACTATTGCAGA
TATTCAAGAAAAAGATAAAGAAACAAGACGTTTCTTTTCACCTCATAAATCTTATCTAGTCAATATTGGAAACATCAAAG
GTTATGACAAAAAAATGCGAGAAATAATTTTTTATGAAGATCATCGTTGTCCGATTACTCGAATGAAAATTGGAAAGTTA
AAGGCTATTTTAGAGGAATTAAAAGGATAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-244)

• Response regulator receiver domain (Response_reg) (3-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	70.204	98.394	0.691
comE/comE2	Streptococcus gordonii strain NCTC7865	70.082	97.992	0.687
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	70.082	97.992	0.687
comE	Streptococcus mitis SK321	69.388	98.394	0.683
comE	Streptococcus pneumoniae TIGR4	68.98	98.394	0.679
comE	Streptococcus pneumoniae Rx1	68.98	98.394	0.679
comE	Streptococcus infantis strain Atu-4	68.98	98.394	0.679
comE	Streptococcus pneumoniae D39	68.98	98.394	0.679
comE	Streptococcus pneumoniae R6	68.98	98.394	0.679
comE/blpR	Streptococcus mutans UA159	40.081	99.197	0.398