Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QUD80_RS04475 Genome accession   NZ_AP027302
Coordinates   928354..929652 (+) Length   432 a.a.
NCBI ID   WP_286306190.1    Uniprot ID   -
Organism   Enterococcus faecalis strain N4E     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 923354..934652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUD80_RS04450 (N4E_08530) - 924344..925134 (-) 791 Protein_851 hypothetical protein -
  QUD80_RS04455 (N4E_08540) - 925298..925681 (+) 384 WP_104675218.1 YccF domain-containing protein -
  QUD80_RS04460 (N4E_08550) - 925770..926195 (+) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  QUD80_RS04465 (N4E_08560) - 926254..926883 (+) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  QUD80_RS04470 (N4E_08570) - 926963..928162 (-) 1200 WP_002370127.1 hypothetical protein -
  QUD80_RS04475 (N4E_08580) cinA 928354..929652 (+) 1299 WP_286306190.1 competence/damage-inducible protein A Machinery gene
  QUD80_RS04480 (N4E_08590) recA 929711..930757 (+) 1047 WP_002354860.1 recombinase RecA Machinery gene
  QUD80_RS04485 (N4E_08600) - 930917..931222 (+) 306 WP_010821936.1 hypothetical protein -
  QUD80_RS04490 (N4E_08610) - 931227..932477 (+) 1251 WP_174113969.1 PTS transporter subunit EIIC -
  QUD80_RS04495 (N4E_08620) - 932497..932838 (+) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  QUD80_RS04500 (N4E_08630) - 932820..934283 (+) 1464 WP_248848854.1 glycoside hydrolase family 1 protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 46969.27 Da        Isoelectric Point: 4.5410

>NTDB_id=100759 QUD80_RS04475 WP_286306190.1 928354..929652(+) (cinA) [Enterococcus faecalis strain N4E]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTIAECFHFNRDRNYIRQSAVM
RGLDLCGAESLIKNKYANVCSVFSCFFGTKEI

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=100759 QUD80_RS04475 WP_286306190.1 928354..929652(+) (cinA) [Enterococcus faecalis strain N4E]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTAATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCATTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTGCGGCGCCGAATCATTAATAAAAAATAAATATGCGAATGTTTGTTCGGTTTTTTCTTGCTTTTT
TGGTACAAAAGAGATATGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-405)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.267

96.991

0.507
  cinA Streptococcus mitis SK321

51.799

96.528

0.5
  cinA Streptococcus mitis NCTC 12261

51.559

96.528

0.498
  cinA Streptococcus pneumoniae TIGR4

50.839

96.528

0.491
  cinA Streptococcus pneumoniae D39

50.6

96.528

0.488
  cinA Streptococcus pneumoniae Rx1

50.36

96.528

0.486
  cinA Streptococcus pneumoniae R6

50.36

96.528

0.486
  cinA Bacillus subtilis subsp. subtilis str. 168

48.395

93.75

0.454
  cinA Streptococcus suis isolate S10

44.01

94.676

0.417

Multiple sequence alignment