Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   ABKJ27_RS00065 Genome accession   NZ_CP157578
Coordinates   5883..6005 (+) Length   40 a.a.
NCBI ID   WP_045612506.1    Uniprot ID   Q9X989
Organism   Streptococcus sp. KHUD_011     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 883..11005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS00040 (ABKJ27_00045) dnaA 1365..2726 (-) 1362 WP_084950575.1 chromosomal replication initiator protein DnaA -
  ABKJ27_RS00045 (ABKJ27_00050) spo0J 2939..3697 (-) 759 WP_410011773.1 ParB/RepB/Spo0J family partition protein Regulator
  ABKJ27_RS00050 (ABKJ27_00055) htrA 3755..4936 (-) 1182 WP_410011774.1 S1C family serine protease Regulator
  ABKJ27_RS00055 (ABKJ27_00060) rlmH 5120..5599 (+) 480 WP_410011775.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ABKJ27_RS00065 (ABKJ27_00070) comC/comC2 5883..6005 (+) 123 WP_045612506.1 competence-stimulating peptide ComC Regulator
  ABKJ27_RS00070 (ABKJ27_00075) comD/comD1 6018..7343 (+) 1326 WP_410011776.1 competence system sensor histidine kinase ComD Regulator
  ABKJ27_RS00075 (ABKJ27_00080) comE 7340..8092 (+) 753 WP_410011777.1 competence system response regulator transcription factor ComE Regulator
  ABKJ27_RS00090 (ABKJ27_00095) - 8334..8876 (-) 543 WP_001158275.1 TetR/AcrR family transcriptional regulator -

Sequence


Protein


Download         Length: 40 a.a.        Molecular weight: 4734.60 Da        Isoelectric Point: 11.0565

>NTDB_id=1007423 ABKJ27_RS00065 WP_045612506.1 5883..6005(+) (comC/comC2) [Streptococcus sp. KHUD_011]
MKNTVKLEQFVALKEKDLQKIQGGEMRKPDGALFNLFRRR

Nucleotide


Download         Length: 123 bp        

>NTDB_id=1007423 ABKJ27_RS00065 WP_045612506.1 5883..6005(+) (comC/comC2) [Streptococcus sp. KHUD_011]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCCTTGAAGGAAAAAGACTTGCAAAAGATTCAAGGTGGGGAGATGAG
GAAACCAGATGGTGCTTTATTTAATTTATTTAGAAGAAGATAA

Domains


Predicted by InterproScan.

(1-27)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q9X989

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

75

100

0.75

  comC/comC2 Streptococcus pneumoniae TIGR4

75

100

0.75

  comC Streptococcus mitis NCTC 12261

65

100

0.65

  comC Streptococcus mitis SK321

89.655

72.5

0.65

  comC/comC1 Streptococcus pneumoniae G54

96.296

67.5

0.65

  comC/comC1 Streptococcus pneumoniae D39

96.296

67.5

0.65

  comC/comC1 Streptococcus pneumoniae Rx1

96.296

67.5

0.65

  comC/comC1 Streptococcus pneumoniae R6

96.296

67.5

0.65


Multiple sequence alignment