Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   ABKJ27_RS00070 Genome accession   NZ_CP157578
Coordinates   6018..7343 (+) Length   441 a.a.
NCBI ID   WP_410011776.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1018..12343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS00040 (ABKJ27_00045) dnaA 1365..2726 (-) 1362 WP_084950575.1 chromosomal replication initiator protein DnaA -
  ABKJ27_RS00045 (ABKJ27_00050) spo0J 2939..3697 (-) 759 WP_410011773.1 ParB/RepB/Spo0J family partition protein Regulator
  ABKJ27_RS00050 (ABKJ27_00055) htrA 3755..4936 (-) 1182 WP_410011774.1 S1C family serine protease Regulator
  ABKJ27_RS00055 (ABKJ27_00060) rlmH 5120..5599 (+) 480 WP_410011775.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ABKJ27_RS00065 (ABKJ27_00070) comC/comC2 5883..6005 (+) 123 WP_045612506.1 competence-stimulating peptide ComC Regulator
  ABKJ27_RS00070 (ABKJ27_00075) comD/comD1 6018..7343 (+) 1326 WP_410011776.1 competence system sensor histidine kinase ComD Regulator
  ABKJ27_RS00075 (ABKJ27_00080) comE 7340..8092 (+) 753 WP_410011777.1 competence system response regulator transcription factor ComE Regulator
  ABKJ27_RS00090 (ABKJ27_00095) - 8334..8876 (-) 543 WP_001158275.1 TetR/AcrR family transcriptional regulator -
  ABKJ27_RS00095 (ABKJ27_00100) - 9004..11646 (+) 2643 WP_410011778.1 YhgE/Pip family protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51053.54 Da        Isoelectric Point: 6.4342

>NTDB_id=1007424 ABKJ27_RS00070 WP_410011776.1 6018..7343(+) (comD/comD1) [Streptococcus sp. KHUD_011]
MDFFLVVDFILYFLILSHSYHLICKGQIKAKELYVFGAYTLLVEAVLELPFYFLSLDGLGIVTFLFPLGLYSYFRWIKQY
ESDRGLFLSLLLSLLYESTHTFLSVTFSSITGDNFVLQYYGLFFFVVTVLTYFVILKIIHYFHLELAYFDKDYLYPFLKK
VFFALLLLHIVSFVSDIVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKEQMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDTITKLPIDLLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLSNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1007424 ABKJ27_RS00070 WP_410011776.1 6018..7343(+) (comD/comD1) [Streptococcus sp. KHUD_011]
ATGGATTTTTTCTTAGTAGTGGATTTTATATTATATTTTCTAATTCTTAGTCACAGTTACCATTTAATTTGTAAAGGTCA
AATAAAAGCAAAGGAACTATACGTTTTTGGTGCTTATACATTATTAGTAGAAGCAGTACTTGAACTTCCCTTCTATTTTC
TATCTTTAGATGGGTTAGGAATTGTAACATTTTTATTTCCTTTGGGATTATATTCCTATTTTCGATGGATCAAACAGTAT
GAGAGTGATAGAGGACTATTTCTAAGTTTACTACTATCTCTTTTATATGAGAGCACTCATACCTTTCTGTCTGTAACTTT
CTCCTCTATAACAGGAGACAATTTTGTTCTACAATATTATGGCCTATTCTTTTTCGTTGTAACGGTGTTGACCTATTTTG
TTATCTTAAAAATCATTCATTATTTCCATTTGGAACTAGCCTATTTTGACAAAGACTACCTCTACCCTTTCTTGAAAAAA
GTATTTTTTGCTTTACTATTGCTACATATTGTATCTTTCGTTTCAGATATAGTAAGTACAATTAAACATTTGAATAGTTT
TGGAAGTATTTTATCATCTATTGTCTTTATATCGTTACTTTTGACCTTCTTTGCAATGAATTCTCATAAAGAACAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTATACAGATGAAATTGTCGGACTGTAT
AATGAAATCCGTGGTTTTCGACATGACTATGCTGGGATGCTTGTCAGCATGCAGATGGCAATTGACAGTGGTAATTTACA
GGAAATTGACAGAGTTTACAATGAAGTTTTGGTCAAAGCAAATCACAAACTGCGTTCAGATAAGTATACTTACTTTGACT
TGAACAACATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTATATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATACGATTACCAAGCTTCCAATAGACCTGCTAGATTTAGTTCGTATTATGAGTGTTTTATTGAA
CAATGCTGTCGAAGGATCGGCTGATAGTTATAAAAAGCAGATGGAAGTAGCAGTTATTAAGATGGAAACTGAAACAGTGA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCTTTAGGATTCTCTACTAAGGGAAGA
AATCGTGGAGTCGGATTAAGTAATGTGAAAGAACTACTGGATAAGTACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATCATTAGGTTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(335-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus pneumoniae Rx1

91.61

100

0.916
  comD/comD1 Streptococcus pneumoniae D39

91.61

100

0.916
  comD/comD1 Streptococcus pneumoniae R6

91.61

100

0.916
  comD/comD2 Streptococcus pneumoniae TIGR4

91.383

100

0.914
  comD Streptococcus mitis SK321

91.156

100

0.912
  comD Streptococcus mitis NCTC 12261

87.302

100

0.873
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50

85.261

0.426
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.604

85.941

0.426

Multiple sequence alignment