Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   GPW69_RS03415 Genome accession   NZ_LR738724
Coordinates   665532..666194 (+) Length   220 a.a.
NCBI ID   WP_074391486.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 660532..671194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS03395 - 660982..661911 (-) 930 WP_074391490.1 ABC transporter substrate-binding protein -
  GPW69_RS03400 - 661924..662709 (-) 786 WP_074391489.1 ABC transporter ATP-binding protein -
  GPW69_RS03405 - 662861..664306 (-) 1446 WP_074391488.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  GPW69_RS03410 - 664718..665464 (+) 747 WP_074391487.1 lysophospholipid acyltransferase family protein -
  GPW69_RS03415 comEA/celA/cilE 665532..666194 (+) 663 WP_074391486.1 helix-hairpin-helix domain-containing protein Machinery gene
  GPW69_RS03420 comEC/celB 666178..668415 (+) 2238 WP_074391485.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23499.00 Da        Isoelectric Point: 3.9430

>NTDB_id=1007144 GPW69_RS03415 WP_074391486.1 665532..666194(+) (comEA/celA/cilE) [Streptococcus suis isolate 9401240]
MDTIKTYIEMFKEYKWQIALPAAAGLLLTTFLIFSQPAKSDQTGLTDFPQTEQTSNSSELVEETSTEVSEEPSQLVVDVK
GAVTEPGLYTLEADARVNDAVDAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSQEEKNTDLVN
LNTATEADLQTISGIGAKRAADIIAYRETNGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1007144 GPW69_RS03415 WP_074391486.1 665532..666194(+) (comEA/celA/cilE) [Streptococcus suis isolate 9401240]
ATGGATACAATCAAAACTTATATAGAAATGTTTAAAGAATACAAGTGGCAGATTGCTCTACCAGCAGCTGCAGGTTTGCT
TCTGACAACATTCTTAATTTTCAGCCAACCTGCCAAGTCTGATCAGACAGGACTGACAGACTTTCCACAGACCGAGCAAA
CTTCTAATAGCTCTGAGTTGGTCGAGGAAACCAGTACAGAAGTAAGTGAGGAGCCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTGACAGAGCCAGGGCTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGATGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCTAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGGTCTACGTGGCTAGTAAGG
ACGAAAATATCTCGGTGGTTGCCAGCACGACTGCCAGCTCTGCCATGTCCCAAGAAGAAAAAAACACTGATCTAGTCAAT
CTCAACACGGCGACCGAGGCTGACCTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGACAAACGGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTATCGGGTATCGGCGACAAGACCATGGAAAGCATCC
GACCTTATGTCACGGTCGATTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(155-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis SK321

45.74

100

0.464
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

45.74

100

0.464
  comEA Streptococcus thermophilus LMD-9

58.642

73.636

0.432
  comEA Bacillus subtilis subsp. subtilis str. 168

39.048

95.455

0.373
  comEA Lactococcus lactis subsp. cremoris KW2

37.327

98.636

0.368

Multiple sequence alignment