Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Regulator
Locus tag   GPW68_RS02805 Genome accession   NZ_LR738723
Coordinates   524783..525532 (+) Length   249 a.a.
NCBI ID   WP_074389180.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0088     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 519783..530532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW68_RS02780 - 520358..520630 (+) 273 WP_074389178.1 DUF3884 family protein -
  GPW68_RS02785 - 520719..520910 (+) 192 WP_024381035.1 hypothetical protein -
  GPW68_RS02790 comA 521112..523262 (+) 2151 WP_074389179.1 peptide cleavage/export ABC transporter Regulator
  GPW68_RS02795 - 523284..523439 (+) 156 WP_000794567.1 hypothetical protein -
  GPW68_RS02800 - 523899..524768 (+) 870 WP_226319201.1 GHKL domain-containing protein -
  GPW68_RS02805 comE 524783..525532 (+) 750 WP_074389180.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  GPW68_RS02810 - 525873..526253 (+) 381 Protein_489 hypothetical protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29360.85 Da        Isoelectric Point: 7.0306

>NTDB_id=1007044 GPW68_RS02805 WP_074389180.1 524783..525532(+) (comE) [Streptococcus suis isolate GD-0088]
MNIIVLDDNIHHQLRLESALYDVAWSLHIHINIECARTIQALREYMNQEEVNQIYFLDLEIGNQKNLGFEIAKEIRNNNP
YAVIIFVTSYSDLMPLVFQYHLSALDFIIKDLKETEFRNRLKQCLEQVIISFKKKSDGELLRYSYQNRTGICIPFSDILF
IQTSVKPHRLIIYTVDFIKEFYGTLNDILDLDSKNYFEKVDRSTIINVDNVTEYSSKTREVKFFEGTTCLVSRLRIKDVK
TRLRNKGII

Nucleotide


Download         Length: 750 bp        

>NTDB_id=1007044 GPW68_RS02805 WP_074389180.1 524783..525532(+) (comE) [Streptococcus suis isolate GD-0088]
ATGAATATTATTGTTCTGGATGACAATATTCATCATCAGTTGCGACTAGAATCTGCTCTTTATGATGTAGCTTGGTCTTT
ACATATTCATATCAATATTGAATGTGCTAGAACAATACAGGCATTAAGAGAGTATATGAATCAAGAAGAAGTAAATCAGA
TATATTTTCTAGATTTAGAAATTGGCAATCAAAAAAATTTAGGTTTTGAGATTGCTAAAGAAATAAGAAATAATAATCCT
TATGCAGTTATTATATTTGTGACTTCATATTCCGACTTGATGCCCCTAGTATTTCAATATCATCTTTCGGCATTAGATTT
TATTATTAAAGATCTTAAAGAAACAGAATTTCGTAATCGGTTAAAGCAGTGTTTGGAACAAGTAATAATTTCATTTAAGA
AAAAATCTGATGGGGAATTGTTAAGATATAGTTACCAGAACAGAACTGGTATCTGCATACCTTTTTCCGATATACTTTTT
ATTCAAACCTCAGTTAAACCGCATCGATTAATTATTTATACAGTAGATTTTATTAAAGAATTTTATGGTACTTTGAATGA
TATACTAGATTTAGATAGTAAGAATTATTTTGAAAAAGTAGATCGTTCAACAATAATAAATGTGGACAATGTTACTGAGT
ACAGTTCGAAAACAAGAGAAGTAAAATTTTTTGAAGGAACAACATGTCTTGTATCTAGATTGAGAATTAAGGATGTAAAA
ACTAGATTAAGAAATAAAGGTATAATATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-243)

Response regulator receiver domain (Response_reg)

(4-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Streptococcus pneumoniae D39

36.614

100

0.373
  comE Streptococcus pneumoniae R6

36.614

100

0.373
  comE Streptococcus pneumoniae TIGR4

36.614

100

0.373
  comE Streptococcus mitis NCTC 12261

36.614

100

0.373
  comE Streptococcus mitis SK321

36.614

100

0.373
  comE Streptococcus pneumoniae Rx1

36.614

100

0.373
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.349

100

0.373
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.349

100

0.373
  comE/blpR Streptococcus mutans UA159

36.948

100

0.369
  comE Streptococcus infantis strain Atu-4

36.546

100

0.365