Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   ABKA22_RS11165 Genome accession   NZ_CP157287
Coordinates   2212910..2213206 (-) Length   98 a.a.
NCBI ID   WP_212715809.1    Uniprot ID   -
Organism   Lactococcus lactis strain BIM B-1834     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2214119..2249572 2212910..2213206 flank 913


Gene organization within MGE regions


Location: 2212910..2249572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKA22_RS11165 (ABKA22_11165) comGC 2212910..2213206 (-) 297 WP_212715809.1 competence type IV pilus major pilin ComGC Machinery gene
  ABKA22_RS11175 (ABKA22_11175) - 2213579..2213644 (-) 66 WP_228762923.1 hypothetical protein -
  ABKA22_RS11180 (ABKA22_11180) - 2214119..2214898 (-) 780 WP_348619035.1 peptidoglycan amidohydrolase family protein -
  ABKA22_RS11185 (ABKA22_11185) - 2214898..2215197 (-) 300 WP_010905918.1 phage holin -
  ABKA22_RS11190 (ABKA22_11190) - 2215210..2215434 (-) 225 WP_023189750.1 hemolysin XhlA family protein -
  ABKA22_RS11195 (ABKA22_11195) - 2215447..2215683 (-) 237 WP_025017282.1 hypothetical protein -
  ABKA22_RS11200 (ABKA22_11200) - 2215694..2219443 (-) 3750 WP_348619036.1 hypothetical protein -
  ABKA22_RS11205 (ABKA22_11205) - 2219443..2220966 (-) 1524 WP_348619037.1 distal tail protein Dit -
  ABKA22_RS11210 (ABKA22_11210) - 2220980..2221120 (-) 141 WP_348619038.1 hypothetical protein -
  ABKA22_RS11215 (ABKA22_11215) - 2221218..2223584 (-) 2367 WP_348619039.1 phage tail tape measure protein -
  ABKA22_RS11220 (ABKA22_11220) - 2223574..2224281 (-) 708 WP_348619040.1 Gp15 family bacteriophage protein -
  ABKA22_RS11225 (ABKA22_11225) - 2224297..2224704 (-) 408 WP_003131323.1 hypothetical protein -
  ABKA22_RS11230 (ABKA22_11230) - 2224761..2225237 (-) 477 WP_014570559.1 hypothetical protein -
  ABKA22_RS11235 (ABKA22_11235) - 2225248..2225682 (-) 435 WP_003131321.1 minor capsid protein -
  ABKA22_RS11240 (ABKA22_11240) - 2225682..2226011 (-) 330 WP_003131320.1 hypothetical protein -
  ABKA22_RS11245 (ABKA22_11245) - 2226008..2226352 (-) 345 WP_014570557.1 putative minor capsid protein -
  ABKA22_RS11250 (ABKA22_11250) - 2226342..2226743 (-) 402 WP_014570556.1 hypothetical protein -
  ABKA22_RS11255 (ABKA22_11255) - 2226817..2227053 (-) 237 WP_014570555.1 Ig-like domain-containing protein -
  ABKA22_RS11260 (ABKA22_11260) - 2227082..2227999 (-) 918 WP_240834885.1 phage capsid protein -
  ABKA22_RS11265 (ABKA22_11265) - 2228014..2229063 (-) 1050 WP_348619041.1 XkdF-like putative serine protease domain-containing protein -
  ABKA22_RS11270 (ABKA22_11270) - 2229079..2229909 (-) 831 WP_348619042.1 phage minor head protein -
  ABKA22_RS11275 (ABKA22_11275) - 2229902..2231431 (-) 1530 WP_348619043.1 phage portal protein -
  ABKA22_RS11280 (ABKA22_11280) - 2231499..2232551 (-) 1053 WP_348619044.1 DUF4062 domain-containing protein -
  ABKA22_RS11285 (ABKA22_11285) - 2232616..2233914 (-) 1299 WP_348619045.1 PBSX family phage terminase large subunit -
  ABKA22_RS11290 (ABKA22_11290) - 2233874..2234374 (-) 501 WP_205468950.1 terminase small subunit -
  ABKA22_RS11295 (ABKA22_11295) - 2234548..2234937 (-) 390 WP_031561062.1 DUF722 domain-containing protein -
  ABKA22_RS11300 (ABKA22_11300) - 2235356..2235670 (-) 315 WP_259760528.1 hypothetical protein -
  ABKA22_RS11305 (ABKA22_11305) - 2235667..2235849 (-) 183 WP_348619046.1 hypothetical protein -
  ABKA22_RS11310 (ABKA22_11310) - 2236068..2236421 (-) 354 WP_032398679.1 hypothetical protein -
  ABKA22_RS11315 (ABKA22_11315) - 2236418..2236603 (-) 186 WP_348619047.1 DUF1660 family phage protein -
  ABKA22_RS11320 (ABKA22_11320) - 2236600..2236833 (-) 234 WP_075070434.1 hypothetical protein -
  ABKA22_RS11325 (ABKA22_11325) - 2237005..2237697 (-) 693 WP_348619048.1 hypothetical protein -
  ABKA22_RS11330 (ABKA22_11330) - 2237684..2238049 (-) 366 WP_289446579.1 hypothetical protein -
  ABKA22_RS11335 (ABKA22_11335) - 2238042..2238503 (-) 462 WP_348619049.1 hypothetical protein -
  ABKA22_RS11340 (ABKA22_11340) - 2238512..2239186 (-) 675 WP_348619050.1 DUF1642 domain-containing protein -
  ABKA22_RS11345 (ABKA22_11345) - 2239183..2239458 (-) 276 WP_289448607.1 hypothetical protein -
  ABKA22_RS11350 (ABKA22_11350) - 2239781..2240191 (-) 411 WP_014570810.1 hypothetical protein -
  ABKA22_RS11355 (ABKA22_11355) - 2240204..2240446 (-) 243 WP_348619051.1 hypothetical protein -
  ABKA22_RS11360 (ABKA22_11360) - 2240439..2241362 (-) 924 WP_348619052.1 phage replisome organizer N-terminal domain-containing protein -
  ABKA22_RS11365 (ABKA22_11365) - 2241637..2242563 (-) 927 WP_348619053.1 RecT family recombinase -
  ABKA22_RS11370 (ABKA22_11370) - 2242560..2243393 (-) 834 WP_095345748.1 hypothetical protein -
  ABKA22_RS11375 (ABKA22_11375) - 2243497..2243739 (-) 243 WP_348619054.1 hypothetical protein -
  ABKA22_RS11380 (ABKA22_11380) - 2243752..2243874 (-) 123 WP_023164646.1 hypothetical protein -
  ABKA22_RS11385 (ABKA22_11385) - 2243871..2244053 (-) 183 WP_003130605.1 hypothetical protein -
  ABKA22_RS11390 (ABKA22_11390) - 2244069..2244758 (-) 690 WP_014570818.1 phage regulatory protein -
  ABKA22_RS11395 (ABKA22_11395) - 2244817..2245050 (-) 234 WP_014570819.1 transcriptional regulator -
  ABKA22_RS11400 (ABKA22_11400) - 2245227..2245637 (+) 411 WP_014570820.1 helix-turn-helix transcriptional regulator -
  ABKA22_RS11405 (ABKA22_11405) - 2245648..2246232 (+) 585 WP_348619055.1 hypothetical protein -
  ABKA22_RS11410 (ABKA22_11410) - 2246288..2246827 (+) 540 WP_023189015.1 PH domain-containing protein -
  ABKA22_RS11415 (ABKA22_11415) - 2246947..2248404 (+) 1458 WP_031561103.1 recombinase family protein -

Sequence

Protein


Download         Length: 98 a.a.        Molecular weight: 11157.84 Da        Isoelectric Point: 4.2213

>NTDB_id=1005458 ABKA22_RS11165 WP_212715809.1 2212910..2213206(-) (comGC) [Lactococcus lactis strain BIM B-1834]
MSFLVTLIEMLIVLAIISILILLFVPNLIKEKSQVQKTGEAAVVKVVESQAQLYELDHDDEKPSLPELLSAGMITQKQIS
AYDNYYDQNKNEERNFND

Nucleotide


Download         Length: 297 bp        

>NTDB_id=1005458 ABKA22_RS11165 WP_212715809.1 2212910..2213206(-) (comGC) [Lactococcus lactis strain BIM B-1834]
ATGAGTTTTTTAGTTACCTTAATTGAGATGTTAATTGTACTAGCTATTATTAGTATTTTAATATTACTATTTGTTCCAAA
TTTAATTAAAGAAAAATCACAAGTTCAAAAAACTGGAGAAGCGGCAGTTGTAAAAGTAGTAGAAAGTCAAGCTCAACTTT
ATGAATTAGATCATGATGATGAGAAGCCGAGTCTGCCAGAATTGCTCAGCGCTGGGATGATTACTCAAAAACAAATTTCT
GCTTACGATAATTACTATGATCAGAACAAAAATGAAGAACGAAATTTTAATGACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

89.247

94.898

0.847
  comGC/cglC Streptococcus mitis SK321

53.333

100

0.571
  comGC/cglC Streptococcus pneumoniae D39

55.914

94.898

0.531
  comGC/cglC Streptococcus pneumoniae R6

55.914

94.898

0.531
  comGC/cglC Streptococcus pneumoniae TIGR4

55.914

94.898

0.531
  comGC/cglC Streptococcus pneumoniae Rx1

55.914

94.898

0.531
  comYC Streptococcus mutans UA140

56.667

91.837

0.52
  comYC Streptococcus mutans UA159

56.667

91.837

0.52
  comGC/cglC Streptococcus mitis NCTC 12261

54.839

94.898

0.52
  comYC Streptococcus gordonii str. Challis substr. CH1

57.303

90.816

0.52
  comYC Streptococcus suis isolate S10

59.74

78.571

0.469

Multiple sequence alignment