Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ABHM42_RS06265 Genome accession   NZ_CP156941
Coordinates   1365848..1367065 (-) Length   405 a.a.
NCBI ID   WP_023435364.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain 2024CK-00455     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1360848..1372065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABHM42_RS06220 (ABHM42_06220) - 1361030..1361479 (-) 450 WP_003094670.1 MOSC domain-containing protein -
  ABHM42_RS06225 (ABHM42_06225) - 1361476..1362105 (-) 630 WP_003094668.1 DUF1780 domain-containing protein -
  ABHM42_RS06230 (ABHM42_06230) - 1362238..1362663 (+) 426 WP_023435363.1 GNAT family N-acetyltransferase -
  ABHM42_RS06235 (ABHM42_06235) - 1362660..1363130 (+) 471 WP_003094664.1 hypothetical protein -
  ABHM42_RS06240 (ABHM42_06240) - 1363127..1363816 (+) 690 WP_003094662.1 energy-coupling factor ABC transporter permease -
  ABHM42_RS06245 (ABHM42_06245) - 1363922..1364131 (+) 210 WP_003094660.1 hypothetical protein -
  ABHM42_RS06250 (ABHM42_06250) yacG 1364168..1364368 (-) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  ABHM42_RS06255 (ABHM42_06255) coaE 1364365..1364976 (-) 612 WP_003094654.1 dephospho-CoA kinase -
  ABHM42_RS06260 (ABHM42_06260) pilD 1364973..1365845 (-) 873 WP_003116251.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  ABHM42_RS06265 (ABHM42_06265) pilC 1365848..1367065 (-) 1218 WP_023435364.1 type II secretion system F family protein Machinery gene
  ABHM42_RS06270 (ABHM42_06270) pilB 1367069..1368772 (-) 1704 WP_003116249.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ABHM42_RS06275 (ABHM42_06275) - 1369001..1369540 (+) 540 WP_031285592.1 pilin -
  ABHM42_RS06280 (ABHM42_06280) - 1369745..1370302 (+) 558 WP_225011032.1 hypothetical protein -
  ABHM42_RS06290 (ABHM42_06290) - 1370545..1370787 (-) 243 WP_023082027.1 hypothetical protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44085.95 Da        Isoelectric Point: 9.8417

>NTDB_id=1003400 ABHM42_RS06265 WP_023435364.1 1365848..1367065(-) (pilC) [Pseudomonas aeruginosa strain 2024CK-00455]
MADKALKTSVFIWEGTDKKGSKVKGELAGQNPMLVKAQLRKQGINPLKVRKKGITLFGAGKKIKPMDIALFTRQMSTMMG
AGVPLLQSFDIIGEGFENPNMRKLVDEIKQDVAAGNSLASSLRKKPIYFDDLYCNLVDAGEQSGALETLLDRVATYKEKT
ESLKAKIKKAMTYPIAVIVVALVVSAILLIKVVPQFQSVFANFGAELPAFTQMVINLSEILQEWWFIVLIGLFAAAFAFR
EVHRRSQKLRDSVDRGLLKLPIIGGILYKSAIARYARTLSTTFAAGVPLVEALDSVSGATGNVVFKNAVTKIKQDVSSGM
QLNFSMRTTNVFPSMAIQMAAIGEESGSLDEMLGKVAGFYEEEVDNAVDNLTTLMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGSVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1003400 ABHM42_RS06265 WP_023435364.1 1365848..1367065(-) (pilC) [Pseudomonas aeruginosa strain 2024CK-00455]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCATCTGGGAAGGCACTGATAAGAAAGGCAGCAAGGTCAAAGGAGAGTT
GGCCGGGCAAAACCCTATGCTGGTGAAGGCTCAACTGCGCAAACAGGGTATCAACCCACTAAAGGTCCGCAAGAAAGGTA
TCACCCTGTTTGGGGCAGGGAAGAAGATTAAGCCCATGGACATCGCCCTGTTCACTCGGCAGATGTCTACCATGATGGGT
GCCGGCGTACCGTTACTGCAATCTTTTGACATCATCGGCGAAGGATTCGAAAATCCAAACATGCGCAAGCTAGTCGATGA
GATCAAGCAGGATGTTGCCGCCGGTAACAGCTTAGCCAGTTCACTTCGAAAGAAACCCATTTACTTCGATGATCTCTACT
GCAACCTAGTCGATGCTGGCGAACAGTCCGGTGCTTTGGAGACATTATTGGATCGGGTAGCAACTTATAAAGAAAAGACA
GAATCCCTGAAAGCCAAAATTAAAAAGGCCATGACTTATCCCATTGCAGTAATTGTAGTGGCCCTTGTGGTGTCGGCGAT
CCTTCTGATAAAAGTGGTCCCACAGTTCCAGTCCGTATTTGCAAATTTTGGCGCCGAGTTGCCGGCCTTTACTCAAATGG
TCATCAATCTTTCCGAGATTCTTCAAGAGTGGTGGTTCATAGTGCTTATTGGTCTTTTTGCCGCAGCTTTTGCATTTAGG
GAAGTTCATCGGCGCTCGCAAAAACTGAGAGATTCAGTAGATCGGGGCCTGCTGAAACTACCTATCATCGGCGGGATACT
TTACAAATCAGCTATCGCCCGCTACGCCCGAACGCTATCCACTACCTTTGCGGCTGGAGTGCCTCTGGTAGAAGCTCTGG
ACTCCGTTTCCGGAGCAACTGGCAACGTGGTATTCAAGAATGCCGTTACCAAGATCAAACAAGACGTGTCCAGCGGCATG
CAATTGAACTTTTCCATGCGCACCACCAATGTTTTCCCCAGTATGGCTATCCAGATGGCTGCAATTGGCGAGGAATCAGG
TTCGCTAGATGAGATGTTAGGAAAAGTTGCCGGTTTCTATGAGGAAGAAGTCGATAACGCCGTCGACAACCTGACAACGT
TGATGGAGCCGATGATCATGGCCGTGCTCGGCGTACTGGTCGGCGGCCTGATCATCGCTATGTATCTACCGATCTTCCAA
CTGGGTTCCGTTGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

79.506

100

0.795
  pilC Acinetobacter baumannii D1279779

60.891

99.753

0.607
  pilC Acinetobacter baylyi ADP1

59.852

100

0.6
  pilC Legionella pneumophila strain ERS1305867

55.051

97.778

0.538
  pilG Neisseria meningitidis 44/76-A

46.269

99.259

0.459
  pilG Neisseria gonorrhoeae MS11

46.02

99.259

0.457
  pilC Vibrio cholerae strain A1552

41.975

100

0.42
  pilC Vibrio campbellii strain DS40M4

40.909

97.778

0.4
  pilC Thermus thermophilus HB27

38.155

99.012

0.378

Multiple sequence alignment